Phospholipid-based matrix effects in LC-MS bioanalysis

Bioanalysis

Volumn 3, Issue 4, 2011, Pages 349-352

  Guo, Xinghua ^a   Lankmayr, Ernst ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

biological matrices; LCMS bioanalysis; matrix effect; phospholipids; sample preparation

Indexed keywords

LYSOPHOSPHOLIPID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID;

BIODIVERSITY; CALIBRATION; CELL POLARITY; CHROMATOGRAPHY; EXTRACELLULAR MATRIX; HIGH THROUGHPUT SCREENING; IONIZATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; METABOLOMICS; MOLECULAR WEIGHT; POLLUTION MONITORING; PRECIPITATION; REVIEW; SOLID PHASE EXTRACTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ARTIFACTS; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; PHOSPHOLIPIDS;

EID: 79952011773     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.10.213     Document Type: Review

References (26)

1. Jemal M, Xia YQ. LC-MS development strategies for quantitative bioanalysis. Curr. Drug Metab. 7, 491-502 (2006).
2. Hofgartner G, Bourgogne E. Quantitative high-throughput analysis of drugs in biological matrices by mass spectrometry. Mass Spectrom. Rev. 22, 195-214 (2003).
3. Trufelli H, Palma P, Famiglini G, Cappiello A. An overview of matrix effects in liquid chromatography-mass spectrometry. Mass Spectrom. Rev. DOI: 10.1002/mas.20298 (2010) (Epub ahead of print).
4. Chiu ML, Lawi W, Snyder ST, Wong PK, Liao JC, Gau V. Matrix effects - a challenge toward automation of molecular analysis. J. Assoc. Lab. Autom. 15, 233-242 (2010).
5. Kebarle P, Tang L. From ions in solution to ions in the gas phase - the mechanism of electrospray mass spectrometry. Anal. Chem. 65, 972A-986A (1993).
6. Bennett P, Meng M, Čápka V. Managing phospholipids-based matrix effects in bioanalysis. Proceedings of: The 17th International Mass Spectrometry Conference (IMSC), Prague, Czech Republic, 1 September 2006.
7. 31P NMR spectroscopy. Anal. Biochem. 185, 299-303 (1990). (Pubitemid 20107166)
8. Moumtzi A, Trenker M, Flicker K, Zenzmaier E, Saf R, Hermetter A. Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells. J. Lipid Res. 48, 565-582 (2007). (Pubitemid 46397460)
9. Taguchi R, Hayakawa J, Takeuchi Y, Ishida M. Two-dimensional analysis of phospholipids by capillary liquid chromatography-electrospray ionization mass spectrometry. J. Mass Spectrom. 35, 953-966 (2000). (Pubitemid 30628123)
10. Han X, Gross RW. Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom. Rev. 24, 367-412 (2005). (Pubitemid 40665798)
11. Quehenberger O, Armando AM, Brown AH et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. J. Lipid Res. 51, 3299-3305 (2010).
12. Alder L, Lüderitz S, Lindtner K, Stan HJ. The ECHO technique - the more effective way of data evaluation in liquid chromatography-tandem mass spectrometry analysis. J. Chromatogr. A 1058, 67-79 (2004). (Pubitemid 39487205)
13. Liu G, Ji QC, Arnold ME. Identifying, evaluating and controlling bioanalytical risks resulting from nonuniform matrix ion suppression/enhancement and nonlinear liquid chromatography-mass spectrometry assay response. Anal. Chem. 82, 9671-9677 (2010).
14. Chambers E, Wagrowski-Diehl DM, Lu Z, Mazzeoe JR. Systematic and comprehensive strategies for reducing matrix effects in LC-MS/MS analyses. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 852, 22-34 (2007). (Pubitemid 46830084)
15. Du L, White RL. Reducing glycerophosphocholine lipid matrix interference effects in biological fluid asays byusing high-turbulence liquid chromatography. Rapid Commun. Mass Spectrom. 22, 3362-3370 (2008).
16. Bhatt J, Subbaiah G, Singh S. Liquid chromatography-tandem mass spectrometry method for simultaneous determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma. Rapid Commun. Mass Spectrom. 20, 2109-2114 (2005).
17. Xia Y, Jemal M. Phospholipids in liquid chromatography-mass spectrometry bioanalysis: comparison of three tandem mass spectrometric techniques for monitoring plasma phospholipids, the effect of mobile-phase composition on phospholipids elution and the association of phospholipids with matrix effects. Rapid Commun. Mass Spectrom. 23, 2125-2138 (2009).
18. Little JL, Wempe MF, Buchanan CM. Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: examining lipid matrix ionization effects in plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 833, 219-230 (2006).
19. Ismaiel OA, Zhang T, Jenkins RG, Karnes HT. Investigation of endogeneous blood plasma phospholipids, cholesterol and glycerides that contribute to matrix effects in bioanalysis by liquid chromatography-mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878, 3303-3316 (2010).
20. Folch F, Lees M, Sloane Stanley GH. A simple method for the isolation of and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509 (1957).
21. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917 (1959).
22. Suzuki E, Sano A, Kuriki T, Miki T. Improved separation and determination of phospholipids in animal tissue employing solid-phase extraction. Biol. Pharm. Bull. 20, 299-303 (1997). (Pubitemid 27212981)
23. Mess JN, Côté C, Bergeron A, Furtado M, Garofolo F. Selection of HILIC columns to handle matrix effect due to phospholipids. Bioanalysis 1(1), 57-62 (2009).
24. Guo X, Lankmayr E. Multidimensional approaches in LC and MS for phospholipid bioanalysis. Bioanalysis 2(6), 1109-1123 (2010).
25. Stahnke H, Reemtsma T, Alder L. Compensation of matrix effects by postcolumn infusion of a monitor substance in multiresidue analysis with LC-MS/MS. Anal. Chem. 81, 2185-2192 (2009).
26. Côté C, Bergeron A, Mess JN, Furtado M, Garofolo F. Matrix effect elimination during LC-MS/MS bioanalytical method development. Bioanalysis 1(7), 1243-1257 (2009).