-
1
-
-
0033808223
-
The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration
-
The AGIS Investigators
-
The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol 2000; 130:429-440.
-
(2000)
Am J Ophthalmol
, vol.130
, pp. 429-440
-
-
-
2
-
-
44249120315
-
Effect of gene therapy on visual function in Leber's congenital amaurosis
-
DOI 10.1056/NEJMoa0802268
-
Bainbridge JW, Smith AJ, Barker SS, et al. Effect of gene therapy on visual function in Leber's congenital amaurosis. N Engl J Med 2008; 358:2231-2239. (Pubitemid 351724452)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.21
, pp. 2231-2239
-
-
Bainbridge, J.W.B.1
Smith, A.J.2
Barker, S.S.3
Robbie, S.4
Henderson, R.5
Balaggan, K.6
Viswanathan, A.7
Holder, G.E.8
Stockman, A.9
Tyler, N.10
Petersen-Jones, S.11
Bhattacharya, S.S.12
Thrasher, A.J.13
Fitzke, F.W.14
Carter, B.J.15
Rubin, G.S.16
Moore, A.T.17
Ali, R.R.18
-
3
-
-
77956370875
-
Glaucoma: Genes, phenotypes, and new directions for therapy
-
Fan BJ, Wiggs JL. Glaucoma: genes, phenotypes, and new directions for therapy. J Clin Invest 2010; 120:3064-3072.
-
(2010)
J Clin Invest
, vol.120
, pp. 3064-3072
-
-
Fan, B.J.1
Wiggs, J.L.2
-
4
-
-
0032885965
-
Herpes simplex virus mediated gene transfer to primate ocular tissues
-
DOI 10.1006/exer.1999.0711
-
Liu X, Brandt CR, Gabelt BT, et al. Herpes simplex virus mediated gene transfer to primate ocular tissues. Exp Eye Res 1999; 69:385-395. (Pubitemid 29469906)
-
(1999)
Experimental Eye Research
, vol.69
, Issue.4
, pp. 385-395
-
-
Liu, X.1
Brandt, C.R.2
Gabelt, B.T.3
Bryar, P.J.4
Smith, M.E.5
Kaufman, P.L.6
-
5
-
-
62549088292
-
Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway in nonhuman primates
-
Barraza RA, Rasmussen CA, Lowen N, et al. Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway in nonhuman primates. Hum Gene Ther 2009; 20:191-200.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 191-200
-
-
Barraza, R.A.1
Rasmussen, C.A.2
Lowen, N.3
-
6
-
-
75749107904
-
Self-complementary AAV virus safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys
-
This study demonstrates effective long-term transgene expression in the trabecular meshwork of rats and monkeys following an intracameral injection of a new-generation self-complementary adeno-associated virus
-
Buie L, Rasmussen CA, Porterfield EC, et al. Self-complementary AAV virus safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. IOVS 2010; 51:236-247. This study demonstrates effective long-term transgene expression in the trabecular meshwork of rats and monkeys following an intracameral injection of a new-generation self-complementary adeno-associated virus.
-
(2010)
IOVS
, vol.51
, pp. 236-247
-
-
Buie, L.1
Rasmussen, C.A.2
Porterfield, E.C.3
-
7
-
-
65549157079
-
Effect of CNTF on retinal ganglion cell survival in experimental glaucoma
-
Pease ME, Zack DJ, Berlincke C, et al. Effect of CNTF on retinal ganglion cell survival in experimental glaucoma. IOVS 2009; 50:2194-2200.
-
(2009)
IOVS
, vol.50
, pp. 2194-2200
-
-
Pease, M.E.1
Zack, D.J.2
Berlincke, C.3
-
8
-
-
0031935860
-
Introduction of DNA into the rat and primate trabecular meshwork by fusogenic liposomes
-
Hangai M, Tanihara H, Honda Y, Kaneda Y. Introduction of DNA into the rat and primate trabecular meshwork by fusogenic liposomes. Invest Ophthalmol Vis Sci 1998; 39:509-516. (Pubitemid 28110682)
-
(1998)
Investigative Ophthalmology and Visual Science
, vol.39
, Issue.3
, pp. 509-516
-
-
Hangai, M.1
Tanihara, H.2
Honda, Y.3
Kaneda, Y.4
-
9
-
-
79951955846
-
Efficacy of topically administered siRNAs in glaucoma treatment: In vivo results in hypertensive model
-
Jimenez A, Mediero A, Loma P, et al. Efficacy of topically administered siRNAs in glaucoma treatment: in vivo results in hypertensive model. IOVS 2009; 50:4054.
-
(2009)
IOVS
, vol.50
, pp. 4054
-
-
Jimenez, A.1
Mediero, A.2
Loma, P.3
-
10
-
-
14644423897
-
Effect of GDNF gene transfer into axotomized retinal ganglion cells using in vivo electroporation with a contact lens-type electrode
-
DOI 10.1038/sj.gt.3302277
-
Ishikawa H, Takano M, Matsumoto N, et al. Effect of GDNF gene transfer into axotomized retinal ganglion cells using in vivo electroporation with a contact lens-type electrode. Gene Ther 2005; 12:289-298. (Pubitemid 40310131)
-
(2005)
Gene Therapy
, vol.12
, Issue.4
, pp. 289-298
-
-
Ishikawa, H.1
Takano, M.2
Matsumoto, N.3
Sawada, H.4
Ide, C.5
Mimura, O.6
Dezawa, M.7
-
11
-
-
0028889647
-
In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells
-
Budenz DL, Bennett J, Alonso L, Maguire A. In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells. Invest Ophthalmol Vis Sci 1995; 36:2211-2215.
-
(1995)
Invest Ophthalmol Vis Sci
, vol.36
, pp. 2211-2215
-
-
Budenz, D.L.1
Bennett, J.2
Alonso, L.3
Maguire, A.4
-
12
-
-
29244491953
-
The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes
-
Liu X, Hu Y, Filla MS, et al. The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes. Mol Vis 2005; 11:1112-1121. (Pubitemid 41819512)
-
(2005)
Molecular Vision
, vol.11
, pp. 1112-1121
-
-
Liu, X.1
Hu, Y.2
Filla, M.S.3
Gabelt, B.T.4
Peters, D.M.5
Brandt, C.R.6
Kaufman, P.L.7
-
13
-
-
33646200546
-
Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
-
Gabelt BT, Hu Y, Vittitow JL, et al. Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments. Exp Eye Res 2006; 82:935-944.
-
(2006)
Exp Eye Res
, vol.82
, pp. 935-944
-
-
Gabelt, B.T.1
Hu, Y.2
Vittitow, J.L.3
-
14
-
-
34547699637
-
Functional delivery of synthetic naked siRNA to the human trabecular meshwork in perfused organ cultures
-
Comes N, Borras T. Functional delivery of synthetic naked siRNA to the human trabecular meshwork in perfused organ cultures. Mol Vis 2007; 13:1363-1374. (Pubitemid 47207739)
-
(2007)
Molecular Vision
, vol.13
, pp. 1363-1374
-
-
Comes, N.1
Borras, T.2
-
15
-
-
36048950352
-
Suppression of keratoepithelin and myocilin by small interfering RNAs (siRNA) in vitro
-
Yuan C, Zins EJ, Clark AF, Huang AJ. Suppression of keratoepithelium and myocilin by small interfering RNAs (siRNA) in vitro. Mol Vis 2007; 13:2083-2095. (Pubitemid 350081945)
-
(2007)
Molecular Vision
, vol.13
, pp. 2083-2095
-
-
Yuan, C.1
Zins, E.J.2
Clark, A.F.3
Huang, A.J.W.4
-
16
-
-
77953243082
-
Development of gene therapy with a glucocorticoidinducible MMP1 for the treatment of steroid glaucoma
-
Spiga MG, Borras T. Development of gene therapy with a glucocorticoidinducible MMP1 for the treatment of steroid glaucoma. IOVS 2010; 51:3029-3041.
-
(2010)
IOVS
, vol.51
, pp. 3029-3041
-
-
Spiga, M.G.1
Borras, T.2
-
17
-
-
77953271012
-
Treatment of sheep steroid-induced ocular hypertension with glucocorticoid-inducible MMP1 gene therapy virus
-
A glucocorticoid-inducible adenoviral vector that expresses recombinant MMP 1 provides a novel approach for the potential treatment of steroid-induced glaucoma
-
Gerometta R, Spiga MG, Borras T, Candia OA. Treatment of sheep steroid-induced ocular hypertension with glucocorticoid-inducible MMP1 gene therapy virus. IOVS 2010; 51:3042-3048. A glucocorticoid-inducible adenoviral vector that expresses recombinant MMP 1 provides a novel approach for the potential treatment of steroid-induced glaucoma.
-
(2010)
IOVS
, vol.51
, pp. 3042-3048
-
-
Gerometta, R.1
Spiga, M.G.2
Borras, T.3
Candia, O.A.4
-
18
-
-
0034759693
-
Stromelysin gene transfer into cultured human trabecular cells and rat trabecular meshwork in vivo
-
Kee C, Sohn S, Hwang JM. Stromelysin gene transfer into cultured human trabecular cells and rat trabecular meshwork in vivo. Invest Ophthalmol Vis Sci 2001; 42:2856-2860. (Pubitemid 33035283)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.12
, pp. 2856-2860
-
-
Kee, C.1
Sohn, S.2
Hwang, J.-M.3
-
19
-
-
77649275883
-
Prostaglandin pathway gene therapy for sustained reduction of intraocular pressure
-
In this study, cyclooxygenase-2 prostaglandin synthesis and its response pathway are engineered through the use of lentiviral vectors expressing COX-2 and the prostaglandin FP receptor in the trabecular meshwork and nonpigmented ciliary epithelium in cats resulting in reduced intraocular pressure
-
Barraza RA, McLaren JW, Poeschla EM. Prostaglandin pathway gene therapy for sustained reduction of intraocular pressure. Mol Ther 2010; 18:491-501. In this study, cyclooxygenase-2 prostaglandin synthesis and its response pathway are engineered through the use of lentiviral vectors expressing COX-2 and the prostaglandin FP receptor in the trabecular meshwork and nonpigmented ciliary epithelium in cats resulting in reduced intraocular pressure.
-
(2010)
Mol Ther
, vol.18
, pp. 491-501
-
-
Barraza, R.A.1
McLaren, J.W.2
Poeschla, E.M.3
-
20
-
-
14044260099
-
L gene transfer
-
DOI 10.1016/j.ymthe.2004.11.014, PII S1525001604015631
-
Malik JM, Shevtova Z, Bahr M, Kugler S. Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transfer. Mol Ther 2005; 11:373-381. (Pubitemid 40277313)
-
(2005)
Molecular Therapy
, vol.11
, Issue.3
, pp. 373-381
-
-
Malik, J.M.I.1
Shevtsova, Z.2
Bahr, M.3
Kugler, S.4
-
21
-
-
0035989022
-
Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model
-
DOI 10.1006/mthe.2002.0608
-
McKinnon SJ, Lehman DM, Tahzib NG, et al. Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model. Mol Ther 2002; 5:780-787. (Pubitemid 34619071)
-
(2002)
Molecular Therapy
, vol.5
, Issue.6
, pp. 780-787
-
-
McKinnon, S.J.1
Lehman, D.M.2
Tahzib, N.G.3
Ransom, N.L.4
Reitsamer, H.A.5
Liston, P.6
LaCasse, E.7
Li, Q.8
Korneluk, R.G.9
Hauswirth, W.W.10
-
22
-
-
32444434448
-
XIAP-mediated neuroprotection in retinal ischemia
-
DOI 10.1038/sj.gt.3302683, PII 3302683
-
Renwick J, Narang MA, Coupland SG, et al. XIAP-mediated neuroprotection in retinal ischemia. Gene Ther 2006; 13:339-347. (Pubitemid 43223103)
-
(2006)
Gene Therapy
, vol.13
, Issue.4
, pp. 339-347
-
-
Renwick, J.1
Narang, M.A.2
Coupland, S.G.3
Xuan, J.Y.4
Baker, A.N.5
Brousseau, J.6
Petrin, D.7
Munger, R.8
Leonard, B.C.9
Hauswirth, W.W.10
Korneluk, R.G.11
Tsilfidis, C.12
-
23
-
-
0032584228
-
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells
-
Di Polo A, Aigner LJ, Dunn RJ, et al. Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells. Proc Natl Acad Sci U S A 1998; 95:3978-3983.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3978-3983
-
-
Di Polo, A.1
Aigner, L.J.2
Dunn, R.J.3
-
24
-
-
0141430092
-
Gene therapy with brain-derived neurotrophic factor as a protection: Retinal ganglion cells in a rat glaucoma model
-
DOI 10.1167/iovs.02-1332
-
Martin KR, Quigley HA, Zack DJ, et al. Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in rat glaucoma model. Invest Ophthalmol Vis Sci 2003; 44:4357-4365. (Pubitemid 37186270)
-
(2003)
Investigative Ophthalmology and Visual Science
, vol.44
, Issue.10
, pp. 4357-4365
-
-
Martin, K.R.G.1
Quigley, H.A.2
Zack, D.J.3
Levkovitch-Verbin, H.4
Kielczewski, J.5
Valenta, D.6
Baumrind, L.7
Pease, M.E.8
Klein, R.L.9
Hauswirth, W.W.10
-
25
-
-
0037095710
-
TrkB Gene Transfer Protects Retinal Ganglion Cells from Axotomy-Induced Death in Vivo
-
Cheng L, Sapieha P, Kittlerova P, et al. TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo. J Neurosci 2002; 22:3977-3986. (Pubitemid 37465706)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.10
, pp. 3977-3986
-
-
Cheng, L.1
Sapieha, P.2
Kittlerova, P.3
Hauswirth, W.W.4
Di, P.A.5
-
26
-
-
0036460130
-
Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo
-
DOI 10.1046/j.1460-9568.2002.01893.x
-
Schmeer C, Straten G, Kugler S, et al. Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo. Eur J Neurosci 2002; 15:637-643. (Pubitemid 35471932)
-
(2002)
European Journal of Neuroscience
, vol.15
, Issue.4
, pp. 637-643
-
-
Schmeer, C.1
Straten, G.2
Kugler, S.3
Gravel, C.4
Bahr, M.5
Isenmann, S.6
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