Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia

International Journal of Radiation Oncology Biology Physics

Volumn 79, Issue 4, 2011, Pages 1188-1195

  Carlson, David J ^a,b   Keall, Paul J ^a   Loo Jr , Billy W ^a   Chen, Zhe J ^b   Brown, J Martin ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell survival; Hypofractionation; Hypoxia; Linear quadratic model; Radiosensitizer

Indexed keywords

CELL SURVIVAL; HYPOFRACTIONATION; HYPOXIA; LINEAR-QUADRATIC MODELS; RADIOSENSITIZERS;

BLOOD VESSELS; CELL CULTURE; CELL PROLIFERATION; DISEASES; FRACTIONATION; OXYGEN; OXYGENATION; POPULATION STATISTICS; PROBABILITY DENSITY FUNCTION; RADIOTHERAPY;

TUMORS;

ARTICLE; BLOOD OXYGEN TENSION; BLOOD VESSEL; CANCER INHIBITION; CANCER RADIOTHERAPY; CAPILLARY WALL; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; DENSITY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; INTERMETHOD COMPARISON; MALE; OXYGENATION; PRIORITY JOURNAL; PROSTATE CANCER; QUANTITATIVE ANALYSIS; RADIATION DOSE FRACTIONATION; SENSITIVITY ANALYSIS; TUMOR CELL; TUMOR HYPOXIA;

ALGORITHMS; CAPILLARIES; CELL HYPOXIA; CELL SURVIVAL; DOSE FRACTIONATION; HEAD AND NECK NEOPLASMS; HUMANS; LINEAR MODELS; MALE; MISONIDAZOLE; OXYGEN CONSUMPTION; PARTIAL PRESSURE; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; TREATMENT FAILURE;

EID: 79951942962     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.10.007     Document Type: Article

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