Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells

Journal of Medical Microbiology

Volumn 60, Issue 3, 2011, Pages 289-299

  Costello, Anne ^a   Herbert, Gillian ^a   Fabunmi, Lydia ^a   Schaffer, Kirsten ^b   Kavanagh, Kevin A ^c   Caraher, Emma M ^a   Callaghan, Máire ^a   McClean, Siobhán ^a  

^a DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^b ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ADULT; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; BURKHOLDERIA CENOCEPACIA; CASE REPORT; CELL INVASION; CELL LINE; CELL POLARITY; CYSTIC FIBROSIS; DEATH; FEMALE; GENUS; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; IN VIVO STUDY; LARVA; LUNG ALVEOLUS EPITHELIUM; MONOLAYER CULTURE; NONHUMAN; PANDORAEA APISTA; PANDORAEA PNOMENUSA; PANDORAEA PULMONICOLA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; SPECIES IDENTIFICATION; SUPERNATANT; SURVIVAL;

ADULT; ANIMALS; BRONCHOPNEUMONIA; BURKHOLDERIA CENOCEPACIA; BURKHOLDERIACEAE; COMMUNICABLE DISEASES, EMERGING; CYSTIC FIBROSIS; EPITHELIAL CELLS; FEMALE; HUMANS; LARVA; LEPIDOPTERA; LUNG; SURVIVAL ANALYSIS; VIRULENCE;

EID: 79951934852     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.022657-0     Document Type: Article

References (29)

1. Atkinson, R. M., Lipuma, J. J., Rosenbluth, D. B. & Dunne, W. M., Jr (2006). Chronic colonization with Pandoraea apista in cystic fibrosis patients determined by repetitive-element-sequence PCR. J Clin Microbiol 44, 833-836.
2. Caraher, E., Collins, J., Herbert, G., Murphy, P. G., Gallagher, C. G., Crowe, M. J., Callaghan, M. & McClean, S. (2008). Evaluation of in vitro virulence characteristics of the genus Pandoraea in lung epithelial cells. J Med Microbiol 57, 15-20.
3. Daneshvar, M. I., Hollis, D. G., Steigerwalt, A. G., Whitney, A. M., Spangler, L., Douglas, M. P., Jordan, J. G., MacGregor, J. P., Hill, B. C. & other authors (2001). Assignment of CDC weak oxidizer group 2 (WO-2) to the genus Pandoraea and characterization of three new Pandoraea genomospecies. J Clin Microbiol 39, 1819-1826.
4. Duff, C., Murphy, P. G., Callaghan, M. & McClean, S. (2006). Differences in invasion and translocation of Burkholderia cepacia complex species in polarised lung epithelial cells in vitro. Microb Pathog 41, 183-192. (Pubitemid 44374301)
5. Flannagan, R. S., Aubert, D., Kooi, C., Sokol, P. A. & Valvano, M. A. (2007). Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo. Infect Immun 75, 1679-1689. (Pubitemid 46559432)
6. Forbes, B. & Ehrhardt, C. (2005). Human respiratory epithelial cell culture for drug delivery applications. Eur J Pharm Biopharm 60, 193-205. (Pubitemid 40804561)
7. Foster, K. A., Avery, M. L., Yazdanian, M. & Audus, K. L. (2000). Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery. Int J Pharm 208, 1-11.
8. Gingues, S., Kooi, C., Visser, M. B., Subsin, B. & Sokol, P. A. (2005). Distribution and expression of the ZmpA metalloprotease in the Burkholderia cepacia complex. J Bacteriol 187, 8247-8255. (Pubitemid 41780489)
9. Jander, G., Rahme, L. G. & Ausubel, F. M. (2000). Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects. J Bacteriol 182, 3843-3845. (Pubitemid 30413039)
10. Johnson, L. N., Han, J. Y., Moskowitz, S. M., Burns, J. L., Qin, X. & Englund, J. A. (2004). Pandoraea bacteremia in a cystic fibrosis patient with associated systemic illness. Pediatr Infect Dis J 23, 881-882. (Pubitemid 40221038)
11. Jørgensen, I. M., Johansen, H. K., Frederiksen, B., Pressler, T., Hansen, A., Vandamme, P., Høiby, N. & Koch, C. (2003). Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients. Pediatr Pulmonol 36, 439-446. (Pubitemid 37296706)
12. Kavanagh, K. & Reeves, E. P. (2004). Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens. FEMS Microbiol Rev 28, 101-112. (Pubitemid 38224509)
13. Kim, J. Y., Sajjan, U. S., Krasan, G. P. & LiPuma, J. J. (2005). Disruption of tight junctions during traversal of the respiratory epithelium by Burkholderia cenocepacia. Infect Immun 73, 7107-7112. (Pubitemid 41587607)
14. Kooi, C., Subsin, B., Chen, R., Pohorelic, B. & Sokol, P. A. (2006). Burkholderia cenocepacia ZmpB is a broad-specificity zinc metalloprotease involved in virulence. Infect Immun 74, 4083-4093. (Pubitemid 43993341)
15. LiPuma, J. J. (2003). Burkholderia and emerging pathogens in cystic fibrosis. Semin Respir Crit Care Med 24, 681-692.
16. McKevitt, A. I. & Woods, D. E. (1984). Characterization of Pseudomonas cepacia isolates from patients with cystic fibrosis. J Clin Microbiol 19, 291-293. (Pubitemid 14185637)
17. Pimentel, J. D. & MacLeod, C. (2008). Misidentification of Pandoraea sputorum isolated from sputum of a patient with cystic fibrosis and review of Pandoraea species infections in transplant patients. J Clin Microbiol 46, 3165-3168.
18. Reeves, E. P., Messina, C. G., Doyle, S. & Kavanagh, K. (2004). Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia 158, 73-79. (Pubitemid 39187856)
19. Schneider, I., Queenan, A. M. & Bauernfeind, A. (2006). Novel carbapenem-hydrolyzing oxacillinase OXA-62 from Pandoraea pnomenusa. Antimicrob Agents Chemother 50, 1330-1335.
20. Seed, K. D. & Dennis, J. J. (2008). Development of Galleria mellonella as an alternative infection model for the Burkholderia cepacia complex. Infect Immun 76, 1267-1275. (Pubitemid 351428090)
21. Seed, K. D. & Dennis, J. J. (2009). Experimental bacteriophage therapy increases survival of Galleria mellonella larvae infected with clinically relevant strains of the Burkholderia cepacia complex. Antimicrob Agents Chemother 53, 2205-2208.
22. Shen, B. Q., Finkbeiner, W. E., Wine, J. J., Mrsny, R. J. & Widdicombe, J. H. (1994). Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl2 secretion. Am J Physiol 266, L493-L501.
23. Stryjewski, M. E., LiPuma, J. J., Messier, R. H., Jr, Reller, L. B. & Alexander, B. D. (2003). Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation. J Clin Microbiol 41, 2255-2257. (Pubitemid 36576581)
24. Swamy, K. H. & Goldberg, A. L. (1982). Subcellular distribution of various proteases in Escherichia coli. J Bacteriol 149, 1027-1033. (Pubitemid 12101323)
25. Uehlinger, S., Schwager, S., Bernier, S. P., Riedel, K., Nguyen, D. T., Sokol, P. A. & Eberl, L. (2009). Identification of specific and universal virulence factors in Burkholderia cenocepacia strains by using multiple infection hosts. Infect Immun 77, 4102-4110.
26. Vandamme, P., Mahenthiralingam, E., Holmes, B., Coenye, T., Hoste, B., De Vos, P., Henry, D. & Speert, D. P. (2000). Identification and population structure of Burkholderia stabilis sp. nov. (formerly Burkholderia cepacia genomovar IV). J Clin Microbiol 38, 1042-1047. (Pubitemid 30140556)
27. Vonberg, R. P. & Gastmeier, P. (2005). Isolation of infectious cystic fibrosis patients: results of a systematic review. Infect Control Hosp Epidemiol 26, 401-409.
28. Whitby, P. W., Vanwagoner, T. M., Springer, J. M., Morton, D. J., Seale, T. W. & Stull, T. L. (2006). Burkholderia cenocepacia utilizes ferritin as an iron source. J Med Microbiol 55, 661-668.
29. Zlosnik, J. E., Hird, T. J., Fraenkel, M. C., Moreira, L. M., Henry, D. A. & Speert, D. P. (2008). Differential mucoid exopolysaccharide production by members of the Burkholderia cepacia complex. J Clin Microbiol 46, 1470-1473. (Pubitemid 351563593)