In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A-C, produced by Penicillium sp. FKI-4410

Journal of Antibiotics

Volumn 64, Issue 2, 2011, Pages 183-188

  Iwatsuki, Masato ^a   Takada, Shohei ^a   Mori, Mihoko ^a   Ishiyama, Aki ^a   Namatame, Miyuki ^a   Nishihara Tsukashima, Aki ^a   Nonaka, Kenichi ^a   Masuma, Rokuro ^a   Otoguro, Kazuhiko ^a   Shiomi, Kazuro ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

antimalarial activity; Penicillium sp.; puberulic acid; viticolin

Indexed keywords

7 HYDROXYTROPOLONE; ARTEMISININ; ARTESUNATE; CHLOROQUINE; PUBERULIC ACID; STIPITATIC ACID; THUJAPLICIN; TROPOLONE DERIVATIVE; TROPONE DERIVATIVE; UNCLASSIFIED DRUG; VITICOLIN A; VITICOLIN B; VITICOLIN C;

ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CYTOTOXICITY; DRUG DECOMPOSITION; DRUG ISOLATION; DRUG RETENTION; DRUG SOLUBILITY; EMBRYO CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIUM; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CELL LINE; CELL SURVIVAL; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA; MICE; PARASITIC SENSITIVITY TESTS; PENICILLIUM; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; TREATMENT OUTCOME;

PENICILLIUM SP.; PLASMODIUM FALCIPARUM;

EID: 79951932714     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2010.124     Document Type: Article

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