An essential role for diet in exercise-mediated protection against dyslipidemia, inflammation and atherosclerosis in ApoE-/- mice

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Cesar, Liliana ^a   Suarez, Samuel Vasallo ^a   Adi, Jennipher ^a   Adi, Nikhil ^a   Vazquez Padron, Roberto ^a   Yu, Hong ^a   Ma, Qi ^a   Goldschmidt Clermont, Pascal J ^a   Agatston, Arthur ^c   Kurlansky, Paul ^b   Webster, Keith A ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Florida Heart Research Institute   (United States)

^c Agatston Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; C REACTIVE PROTEIN; FISH OIL; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; CYTOKINE; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; BODY WEIGHT; CONTROLLED STUDY; DIET THERAPY; DYSLIPIDEMIA; EXERCISE; EXERCISE INTENSITY; FOOD INTAKE; LIFESTYLE MODIFICATION; LIPID DIET; MALE; MOUSE; NONHUMAN; PROTEIN DIET; RUNNING; SEDENTARY LIFESTYLE; THERAPY EFFECT; ANIMAL; ATHEROSCLEROSIS; BLOOD; DIET; EATING; EVALUATION; GENETICS; INFLAMMATION; KINESIOTHERAPY; MOUSE MUTANT; MULTIMODALITY CANCER THERAPY; PHYSIOLOGY;

MUS;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; COMBINED MODALITY THERAPY; CYTOKINES; DIET; DIET THERAPY; DYSLIPIDEMIAS; EATING; EXERCISE THERAPY; INFLAMMATION; LIPIDS; MALE; MICE; MICE, KNOCKOUT; PHYSICAL CONDITIONING, ANIMAL;

EID: 79951929170     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017263     Document Type: Article

References (49)

1. Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, et al. (2007) Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 116 (9): 1081-93.
2. Cuffe M, (2006) The patient with cardiovascular disease: treatment strategies for preventing major events. Clin Cardiol 29(10) Suppl: II4-12.
3. Rice TW, Lumsden AB, (2006) Optimal medical management of peripheral arterial disease. Vasc Endovascular Surg 40 (4): 312-27.
4. Genest J, (2006) Combination of statin and ezetimibe for the treatment of dyslipidemias and the prevention of coronary artery disease. Can J Cardiol 10: 863-8.
5. Nesto RW, (2005) Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome. Am J Cardiovasc Drugs 5: 379-87.
6. Libby P, (2005) The forgotten majority: unfinished business in cardiovascular risk reduction. J Am Coll Cardiol 46: 1225-8.
7. Foley SM, (2005) Update on risk factors for atherosclerosis: The role of inflammation and apolipoprotein E. Medsurg Nurs 14 (1): 43-50.
8. Muchiteni T, Borden WB, (2009) Improving risk factor modification: a global approach. Curr Cardiol Rep 11 (6): 476-83.
9. Stanner S, (2009) Diet and lifestyle measures to protect the ageing heart. Br J Community Nurs 14 (5): 210-2.
10. Blair SN, Morris JN, (2009) Healthy hearts-and the universal benefits of being physically active: physical activity and health. Ann Epidemiol 19 (4): 253-6.
11. Fontana L, (2008) Calorie restriction and cardiometabolic health. Eur J Cardiovasc Prev Rehabil 15 (1): 3-9.
12. Westman EC, Feinman RD, Mavropoulos JC, Vernon MC, Volek JS, et al. (2007) Low carbohydrate nutrition and metabolism. Am J Clin Nutr 86 (2): 276-84.
13. Batsis JA, Nieto-Martinez RE, Lopez-Jimenez F, (2007) Metabolic syndrome: from global epidemiology to individualized medicine. Clin Pharmacol Ther 82 (5): 509-24.
14. Cuffe M, (2006) The patient with cardiovascular disease: treatment strategies for preventing major events. Clin Cardiol 29(10) Suppl: II4-12.
15. Lakka TA, Bouchard C, (2005) Physical activity, obesity and cardiovascular diseases. Handbook Exp Pharmacol 170: 137-63.
16. Weinheimer EM, Sands LP, Campbell WW, (2010) A systematic review of the separate and combined effects of energy restriction and exercise on fat-free mass in middle-aged and older adults: implications for sarcopenic obesity. Nutr Rev 68 (7): 375-88.
17. Södlerlund A, Fischer A, Johansson T, (2009) Physical activity, diet and behaviour modification in the treatment of overweight and obese adults: a systematic review. Perspect Public Health 129(3): 132-42.
18. Kraus WE, Slentz CA, (2009) Exercise training, lipid regulation, and insulin action: a tangled web of cause and effect. Obesity 17 (Suppl 3): S21-6.
19. Leon AS, Sanchez OA, (2001) Response of blood lipids to exercise training alone or combined with dietary intervention. Med Sci Sports Exerc 33(6) Suppl: S502-S515.
20. Bayturan O, Tuzcu EM, Lavoie A, Hu T, Wolski K, (2010) The metabolic syndrome, its component risk factors, and progression of coronary atherosclerosis. Arch Intern Med 170 (5): 478-84.
21. Libby P, Ridker PM, Maseri A, (2002) Inflammation and atherosclerosis. Circulation 105 (9): 1135-43.
22. Hambrecht R, Adams V, Erbs S, Linke A, Kränkel N, et al. (2003) Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107: 3152-8.
23. Walther C, Möbius-Winkler S, Linke A, Bruegel M, Thiery J, et al. (2008) Regular exercise training compared with percutaneous intervention leads to a reduction of inflammatory markers and cardiovascular events in patients with coronary artery disease. Eur J Cardiovasc Prev Rehabil 15 (1): 107-12.
24. Milani RV, Lavie CJ, Mehra MR, (2004) Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol 43 (6): 1056-61.
25. Kim YJ, Shin YO, Bae JS, Lee JB, Ham JH, et al. (2008) Beneficial effects of cardiac rehabilitation and exercise after percutaneous coronary intervention on hsCRP and inflammatory cytokines in CAD patients. Pflugers Arch 455 (6): 1081-8.
26. Caulin-Glaser T, Falko J, Hindman L, La Londe M, Snow R, (2005) Cardiac rehabilitation is associated with an improvement in C-reactive protein levels in both men and women with cardiovascular disease. J Cardiopulm Rehabil 25 (6): 332-6.
27. Taylor RS, Brown A, Ebrahim S, Jolliffe J, Noorani H, et al. (2004) Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. Am J Med 116 (10): 682-92.
28. Ribeiro F, Alves AJ, Duarte JA, Oliveira J, (2010) Is exercise training an effective therapy targeting endothelial dysfunction and vascular wall inflammation? Int J. Cardiol 41 (3): 214-21.
29. Hambrecht R, Wolf A, Gielen S, Linke A, Hofer J, et al. (2000) Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 342 (7): 454-60.
30. Gielen S, Erbs S, Linke A, Mobius-Winkler S, Schuler G, et al. (2003) Home-based versus hospital-based exercise programs in patients with coronary artery disease: effects on coronary vasomotion. Am Heart J 145 (1).
31. Pynn M, Schaefer K, Konstantinides S, Halle M, (2004) Exercise training reduces neointimal growth and stabilizes vascular lesions developing after injury in apolipoprotein E-deficient mice. Circulation 109: 386-392.
32. Okabe TA, Shimada K, Hattori M, Murayama T, Yokode M, Kita T, et al. (2007) Swimming reduces the severity of atherosclerosis in apolipoprotein E deficient mice by antioxidant effects. Cardiovasc Res 74 (3): 537-45.
33. Shimada K, Kishimoto C, Okabe TA, Hattori M, Murayama T, et al. (2007) Exercise training reduces severity of atherosclerosis in apolipoprotein E knockout mice via nitric oxide. Circ J 71 (7): 1147-51.
34. Morgan LM, Griffin BA, Millward DJ, DeLooy A, Fox KR, et al. (2009) Comparison of the effects of four commercially available weight-loss programmes on lipid-based cardiovascular risk factors. Public Health Nutr 12 (6): 799-807.
35. Jebb SA, Lovegrove JA, Griffin BA, Frost GS, Moore CS, et al. (2010) Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK trial. Am J Clin Nutr 92 (4): 748-58.
36. Pepys MB, Hirschfield MG, (2003) C-reactive protein: a critical update. J Clin Invest 111 (12): 1805-1812.
37. Di Tullio MR, Russo C, Jin Z, Sacco RL, Mohr JP, et al. Aortic Arch Plaques and Risk of Recurrent Stroke and Death. Circulation 119: 2376-2382.
38. Ajijola OA, Dong C, Herderick EE, Ma Q, Goldschmidt-Clermont PJ, et al. (2009) Voluntary Running suppresses proinflammatory cytokines and bone marrow endothelial progenitor cell levels in apolipoprotein-E-deficient mice. Antioxid Redox Signal 11: 15-23.
39. Cardenas GA, Lavie CJ, Cardenas V, Milani RV, McCullough PA, (2008) The importance of recognizing and treating low levels of high-density lipoprotein cholesterol: a new era in atherosclerosis management. Rev Cardiovasc Med 9 (4): 239-58.
40. Williams KJ, (2008) Molecular processes that handle and mishandle dietary lipids. J Clin Invest 118 (10): 3247-59.
41. Blasi C, (2008) The autoimmune origin of atherosclerosis. Atherosclerosis 201: 17-32.
42. Bensinger SJ, Tontonoz P, (2008) Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature 454 (7203): 470-7.
43. Adamu B, Sani MU, Abdu A, (2006) Physical exercise and health: a review. Niger J Med 15 (3): 190-6.
44. Lippincott MF, Carlow A, Desai A, Blum A, Rodrigo M, et al. (2008) Predictors of endothelial function in employees with sedentary occupations in a worksite exercise program. Am J Cardiol 102 (7): 820-4.
45. Lippincott MF, Desai A, Zalos G, Carlow A, De Jesus J, et al. (2008) Relation of endothelial function to cardiovascular risk in women with sedentary occupations and without known cardiovascular disease. Am J Cardiol 102 (3): 348-52.
46. Taylor RS, Brown A, Ebrahim S, Jolliffe J, Noorani H, et al. (2004) Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. Am J Med 116 (10): 682-92.
47. Jolliffe J, Rees K, Taylor RRS, Thompson DR, Oldridge N, et al. (2001) Exercise-based rehabilitation for coronary heart disease. Cochrane Database of Systematic Reviews Issue 1, Edited 2009.
48. Rehman J, Li J, Parvathaneni L, Karlsson G, Panchal VR, Temm CJ, et al. (2004) Exercise acutely increases circulating endothelial progenitor cells and monocyte/macrophage-derived angiogenic cells. J Am Coll Cardiol 43: 2314-8.
49. Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D, et al. (2003) Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 2003 108 (4): 457-63.