An islet-specific pulse of TGF-β abrogates CTL function and promotes β cell survival independent of Foxp3+ T cells

Journal of Immunology

Volumn 186, Issue 4, 2011, Pages 2543-2551

  Wållberg, Maja ^a   Wong, F Susan ^b   Green, E Allison ^a,c  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; CD45 ANTIGEN; GRANZYME B; PERFORIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SELECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; CELL SURVIVAL; CYTOTOXICITY TESTS, IMMUNOLOGIC; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EPITOPES, T-LYMPHOCYTE; FORKHEAD TRANSCRIPTION FACTORS; IMMUNOLOGIC MEMORY; INFLAMMATION MEDIATORS; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 79951847399     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002098     Document Type: Article

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