Current approaches and issues in non-clinical evaluation of abuse and dependence

Journal of Pharmacological and Toxicological Methods

Volumn 63, Issue 2, 2011, Pages 160-167

  Moser, Paul ^a   Wolinsky, Toni ^a   Castagné, Vincent ^a   Duxon, Mark ^a  

^a Porsolt and Partners Pharmacology   (France)

Author keywords

Abuse; Drug discrimination; Primate; Rat; Self administration; Spontaneous withdrawal

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; ALCOHOL; AMFEBUTAMONE; AMPHETAMINE; ANALGESIC AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE; CANNABINOID; COCAINE; DOPAMINE RECEPTOR STIMULATING AGENT; KETAMINE; LYSERGIDE; MODAFINIL; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; NICOTINE; NICOTINIC AGENT; OPIATE; PENTAZOCINE; PSYCHEDELIC AGENT; QUINPIROLE; SEDATIVE AGENT; SEROTONIN 2A RECEPTOR; SEROTONIN AGONIST; SEROTONIN UPTAKE INHIBITOR;

ARTICLE; DRUG ABUSE; DRUG DEPENDENCE; DRUG DISCRIMINATION; DRUG SELF ADMINISTRATION; DRUG WITHDRAWAL; EXPERIMENTAL MODEL; FALSE POSITIVE RESULT; GOOD LABORATORY PRACTICE; HUMAN; MEDICAL ASSESSMENT; MEDICAL RESEARCH; NONHUMAN; PLACE PREFERENCE; PREDICTIVE VALUE; PRIMATE; REINFORCEMENT; SPECIES DIFFERENCE; STIMULUS RESPONSE; TELEMETRY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HUMANS; MODELS, ANIMAL; PRIMATES; RATS; SELF ADMINISTRATION; STREET DRUGS; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS;

ANIMALIA; PRIMATES; RATTUS;

EID: 79951811859     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.09.004     Document Type: Article

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