Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A

Oncogene

Volumn 30, Issue 7, 2011, Pages 865-875

  Savelyeva, I ^a,b   Dobbelstein, M ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

adenovirus; E1A; E1B; p300; p53; Sp1

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A PROTEIN; E1B PROTEIN; GENE PRODUCT; PROTEIN MDM2; PROTEIN P21; PROTEIN P300; PROTEIN P53; PUMA PROTEIN; TRANSCRIPTION FACTOR SP1;

ACETYLATION; ADENOVIRUS 5; ARTICLE; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN CELL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; VIRUS INFECTION; VIRUS MUTANT;

ACETYLATION; ACETYLTRANSFERASES; ADENOVIRUS E1A PROTEINS; ADENOVIRUS E1B PROTEINS; ADENOVIRUS INFECTIONS, HUMAN; ADENOVIRUSES, HUMAN; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; E1A-ASSOCIATED P300 PROTEIN; GENE EXPRESSION REGULATION, VIRAL; HUMANS; MUTATION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS P21(RAS); SP1 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN P53;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 5;

EID: 79951810016     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.461     Document Type: Article

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