The Varicella-Zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Vandevenne, Patricia ^a   Lebrun, Marielle ^a   Mjiyad, Nadia ^b   Ote, Isabelle ^a   Di Valentin, Emmanuel ^a   Habraken, Yvette ^a   Dortu, Estelle ^a   Piette, Jacques ^a   Sadzot Delvaux, Catherine ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERFERON STIMULATED GENE 15; MESSENGER RNA; MICROORGANISM PROTEIN; PROTEIN ORF47; UNCLASSIFIED DRUG; VIRUS PROTEIN; IRF3 PROTEIN, HUMAN; ORF47 PROTEIN, VARICELLA ZOSTER VIRUS; ORF47 PROTEIN, VARICELLA-ZOSTER VIRUS;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; GENE EXPRESSION; GENE TARGETING; HERPES ZOSTER; HOST RESISTANCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UPREGULATION; VARICELLA ZOSTER VIRUS; VIRUS MUTANT; WILD TYPE; ANIMAL; CELL STRAIN HEK293; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

HUMAN HERPESVIRUS 3;

ANIMALS; HEK293 CELLS; HERPESVIRUS 3, HUMAN; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; MICE; MUTATION; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; VIRAL PROTEINS;

EID: 79951801158     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016870     Document Type: Article

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