Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen-activated protein kinase activity

Human Mutation

Volumn 32, Issue 3, 2011, Pages 318-324

  Ma, Chi A ^a   Wang, Hong Ying ^a   Temmerman, Stephane ^a,d   Zhao, Yongge ^a   Wu, Liming ^a   Hornung, Ronald L ^b   Wara, Diane ^c   Jain, Ashish ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

IKBKG; IKK ; MAPK; NEMO; Toll like receptor; Ubiquitination

Indexed keywords

LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; ZINC FINGER PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENDRITIC CELL; DNA FLANKING REGION; ECTODERMAL DYSPLASIA; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MISSENSE MUTATION; PRIORITY JOURNAL; UNITED STATES;

CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ECTODERMAL DYSPLASIA; HUMANS; I-KAPPA B KINASE; IMMUNOLOGIC DEFICIENCY SYNDROMES; LIPOPOLYSACCHARIDES; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NF-KAPPA B; SEQUENCE DELETION; UBIQUITINATION; ZINC FINGERS;

EID: 79951791227     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21439     Document Type: Article

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