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Volumn 16, Issue 2, 2011, Pages 217-226

Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature

Author keywords

BRCA1; D67E; Transition temperature; Ubiquitin ligase; Zn2+ binding

Indexed keywords

ASPARTIC ACID; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA1 PROTEIN; GLUTAMIC ACID; MUTANT PROTEIN; UBIQUITIN PROTEIN LIGASE; ZINC ION;

EID: 79951553885     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-010-0718-y     Document Type: Article
Times cited : (13)

References (53)
  • 2
    • 0028826709 scopus 로고
    • 1:CAS:528:DyaK28XktFSisw%3D%3D 8533776
    • D Ford DF Easton J Peto 1995 Am J Hum Genet 57 1457 1462 1:CAS:528:DyaK28XktFSisw%3D%3D 8533776
    • (1995) Am J Hum Genet , vol.57 , pp. 1457-1462
    • Ford, D.1    Easton, D.F.2    Peto, J.3
  • 3
    • 33749023326 scopus 로고    scopus 로고
    • The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
    • DOI 10.1038/sj.onc.1209874, PII 1209874
    • K Gudmundsdottir A Ashworth 2006 Oncogene 25 5864 5874 1:CAS:528:DC%2BD28XhtVSgurjM 10.1038/sj.onc.1209874 16998501 (Pubitemid 44453442)
    • (2006) Oncogene , vol.25 , Issue.43 , pp. 5864-5874
    • Gudmundsdottir, K.1    Ashworth, A.2
  • 4
    • 75149189204 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD1MXhsF2hs7fF 10.1038/nrm2831 20029420
    • MSY Huen SMH Sy J Chen 2010 Nat Rev Mol Cell Biol 11 138 148 1:CAS:528:DC%2BD1MXhsF2hs7fF 10.1038/nrm2831 20029420
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 138-148
    • Huen, M.S.Y.1    Sy, S.M.H.2    Chen, J.3
  • 9
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • DOI 10.1016/S0092-8674(00)80503-6
    • R Scully J Chen RL Ochs K Keegan M Hoekstra J Feunteun DM Livingston 1997 Cell 90 425 435 1:CAS:528:DyaK2sXlsVKrsrc%3D 10.1016/S0092-8674(00)80503-6 9267023 (Pubitemid 27347233)
    • (1997) Cell , vol.90 , Issue.3 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3    Keegan, K.4    Hoekstra, M.5    Feunteun, J.6    Livingston, D.M.7
  • 10
    • 26244466612 scopus 로고    scopus 로고
    • Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking
    • DOI 10.1002/bies.20277
    • BR Henderson 2005 Bioessays 27 884 893 1:CAS:528:DC%2BD2MXhtVKgsb%2FN 10.1002/bies.20277 16108063 (Pubitemid 41415943)
    • (2005) BioEssays , vol.27 , Issue.9 , pp. 884-893
    • Henderson, B.R.1
  • 11
    • 70349982566 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD1MXhtlWisLbI 10.1016/j.cellsig.2009.09.007 19766185
    • MTS Mok BR Henderson 2010 Cell Signal 22 47 56 1:CAS:528: DC%2BD1MXhtlWisLbI 10.1016/j.cellsig.2009.09.007 19766185
    • (2010) Cell Signal , vol.22 , pp. 47-56
    • Mok, M.T.S.1    Henderson, B.R.2
  • 12
    • 70450224250 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD1MXhsV2lu7jP 10.1016/j.cellsig.2009.09.034 19796682
    • KM Brodie BR Henderson 2010 Cell Signal 22 291 302 1:CAS:528: DC%2BD1MXhsV2lu7jP 10.1016/j.cellsig.2009.09.034 19796682
    • (2010) Cell Signal , vol.22 , pp. 291-302
    • Brodie, K.M.1    Henderson, B.R.2
  • 15
    • 0037076672 scopus 로고    scopus 로고
    • Autoubiquitination of the BRCA1·BARD1 RING ubiquitin ligase
    • DOI 10.1074/jbc.M201252200
    • A Chen FE Kleiman JL Manley T Ouchi Z-Q Pan 2002 J Biol Chem 277 22085 22092 1:CAS:528:DC%2BD38Xksl2jtrc%3D 10.1074/jbc.M201252200 11927591 (Pubitemid 34952363)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.24 , pp. 22085-22092
    • Chen, A.1    Kleiman, F.E.2    Manley, J.L.3    Ouchi, T.4
  • 16
    • 0042317328 scopus 로고    scopus 로고
    • The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
    • DOI 10.1074/jbc.C300249200
    • F Wu-Baer K Lagrazon W Yuan R Baer 2003 J Biol Chem 278 34743 34746 1:CAS:528:DC%2BD3sXntVWqs7k%3D 10.1074/jbc.C300249200 12890688 (Pubitemid 37102231)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.37 , pp. 34743-34746
    • Wu-Baer, F.1    Lagrazon, K.2    Yuan, W.3    Baer, R.4
  • 18
    • 77952652312 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BC3cXnsFKgs74%3D 10.1128/MCB.01056-09 20351172
    • F Wu-Baer T Ludwig R Baer 2010 Mol Cell Biol 30 2787 2798 1:CAS:528:DC%2BC3cXnsFKgs74%3D 10.1128/MCB.01056-09 20351172
    • (2010) Mol Cell Biol , vol.30 , pp. 2787-2798
    • Wu-Baer, F.1    Ludwig, T.2    Baer, R.3
  • 22
    • 40149110668 scopus 로고    scopus 로고
    • The ubiquitin E3 ligase activity of BRCA1 and its biological functions
    • DOI 10.1186/1747-1028-3-1
    • W Wu A Koike T Takeshita T Ohta 2008 Cell Div 3 1 1:CAS:528: DC%2BD1cXovVSnsrg%3D 10.1186/1747-1028-3-1 18179693 (Pubitemid 351325350)
    • (2008) Cell Division , vol.3 , pp. 1
    • Wu, W.1    Koike, A.2    Takeshita, T.3    Ohta, T.4
  • 24
    • 77349113419 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BC3cXisFOqs7o%3D 10.1056/NEJMcibr0912412 20181978
    • WD Foulkes 2010 N Engl J Med 362 755 756 1:CAS:528:DC%2BC3cXisFOqs7o%3D 10.1056/NEJMcibr0912412 20181978
    • (2010) N Engl J Med , vol.362 , pp. 755-756
    • Foulkes, W.D.1
  • 25
    • 0035798565 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD3MXosVKgtLs%3D 10.1074/jbc.M106551200 11526114
    • PS Brzovic JE Meza MC King RE Klevit 2001 J Biol Chem 276 41399 41406 1:CAS:528:DC%2BD3MXosVKgtLs%3D 10.1074/jbc.M106551200 11526114
    • (2001) J Biol Chem , vol.276 , pp. 41399-41406
    • Brzovic, P.S.1    Meza, J.E.2    King, M.C.3    Klevit, R.E.4
  • 29
    • 77956196689 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BC3cXhtVKjsbbM 10.1002/cbdv.200900308 20730959
    • A Atipairin B Canyuk A Ratanaphan 2010 Chem Biodivers 7 1949 1967 1:CAS:528:DC%2BC3cXhtVKjsbbM 10.1002/cbdv.200900308 20730959
    • (2010) Chem Biodivers , vol.7 , pp. 1949-1967
    • Atipairin, A.1    Canyuk, B.2    Ratanaphan, A.3
  • 30
    • 0016175456 scopus 로고
    • 1:CAS:528:DyaE2MXht12kug%3D%3D 10.1016/0003-2697(74)90344-3 4606527
    • G Engel 1974 Anal Biochem 61 184 191 1:CAS:528:DyaE2MXht12kug%3D%3D 10.1016/0003-2697(74)90344-3 4606527
    • (1974) Anal Biochem , vol.61 , pp. 184-191
    • Engel, G.1
  • 31
    • 32144432437 scopus 로고    scopus 로고
    • The SWISS-MODEL workspace: A web-based environment for protein structure homology modelling
    • DOI 10.1093/bioinformatics/bti770
    • K Arnold L Bordoli J Kopp T Schwede 2006 Bioinformatics 22 195 201 1:CAS:528:DC%2BD28XovVCltw%3D%3D 10.1093/bioinformatics/bti770 16301204 (Pubitemid 43205406)
    • (2006) Bioinformatics , vol.22 , Issue.2 , pp. 195-201
    • Arnold, K.1    Bordoli, L.2    Kopp, J.3    Schwede, T.4
  • 32
    • 0019873820 scopus 로고
    • 1:CAS:528:DyaL3MXis12nsg%3D%3D 10.1021/bi00504a006 7470476
    • SW Provencher J Glöckner 1981 Biochemistry 20 33 37 1:CAS:528:DyaL3MXis12nsg%3D%3D 10.1021/bi00504a006 7470476
    • (1981) Biochemistry , vol.20 , pp. 33-37
    • Provencher, S.W.1    Glöckner, J.2
  • 33
    • 34548847733 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD2sXhtFGjtLrM 10.1038/nprot.2006.202 17406547
    • NJ Greenfield 2006 Nat Protoc 1 2876 2890 1:CAS:528:DC%2BD2sXhtFGjtLrM 10.1038/nprot.2006.202 17406547
    • (2006) Nat Protoc , vol.1 , pp. 2876-2890
    • Greenfield, N.J.1
  • 35
    • 0027367252 scopus 로고
    • 1:CAS:528:DyaK2cXlsFWnu7Y%3D 10.1002/pro.5560021222 8298466
    • P Pjura BW Matthews 1993 Protein Sci 2 2226 2232 1:CAS:528: DyaK2cXlsFWnu7Y%3D 10.1002/pro.5560021222 8298466
    • (1993) Protein Sci , vol.2 , pp. 2226-2232
    • Pjura, P.1    Matthews, B.W.2
  • 36
    • 0038237514 scopus 로고    scopus 로고
    • Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein
    • DOI 10.1074/jbc.M204591200
    • Y Xia GM Pao H-W Chen IM Verma T Hunter 2003 J Biol Chem 278 5255 5263 1:CAS:528:DC%2BD3sXhtVKltbs%3D 10.1074/jbc.M204591200 12431996 (Pubitemid 36801039)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.7 , pp. 5255-5263
    • Xia, Y.1    Pao, G.M.2    Chen, H.-W.3    Verma, I.M.4    Hunter, T.5
  • 37
    • 33644850903 scopus 로고    scopus 로고
    • A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination
    • DOI 10.1016/j.molcel.2006.02.008, PII S1097276506000906
    • PS Brzovic A Lissounov DE Christensen DW Hoyt RE Kelvit 2006 Mol Cell 21 873 880 1:CAS:528:DC%2BD28XjtVyisr4%3D 10.1016/j.molcel.2006.02.008 16543155 (Pubitemid 43376136)
    • (2006) Molecular Cell , vol.21 , Issue.6 , pp. 873-880
    • Brzovic, P.S.1    Lissounov, A.2    Christensen, D.E.3    Hoyt, D.W.4    Klevit, R.E.5
  • 38
    • 0037122004 scopus 로고    scopus 로고
    • Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
    • DOI 10.1093/emboj/cdf691
    • DL Mallery CJ Vandenberg K Hiom 2002 EMBO J 21 6755 6762 1:CAS:528:DC%2BD38XpslOgs7Y%3D 10.1093/emboj/cdf691 12485996 (Pubitemid 36014547)
    • (2002) EMBO Journal , vol.21 , Issue.24 , pp. 6755-6762
    • Mallery, D.L.1    Vandenberg, C.J.2    Hiom, K.3
  • 40
    • 70350043057 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD1MXht1egsb%2FF 10.3390/ijms10094187 19865540
    • M Pongsavee P Patmasiriwat GF Saunders 2009 Int J Mol Sci 10 4187 4197 1:CAS:528:DC%2BD1MXht1egsb%2FF 10.3390/ijms10094187 19865540
    • (2009) Int J Mol Sci , vol.10 , pp. 4187-4197
    • Pongsavee, M.1    Patmasiriwat, P.2    Saunders, G.F.3
  • 42
    • 32244435753 scopus 로고    scopus 로고
    • A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats
    • DOI 10.1016/j.canlet.2005.03.012, PII S0304383505002260
    • M Tsuzuki W Wu H Nishikawa R Hayami D Oyake Y Yabuki M Fukuda T Ohta 2006 Cancer Lett 233 108 116 1:CAS:528:DC%2BD28XhtlGiu7k%3D 10.1016/j.canlet.2005. 03.012 15878232 (Pubitemid 43214568)
    • (2006) Cancer Letters , vol.233 , Issue.1 , pp. 108-116
    • Tsuzuki, M.1    Wu, W.2    Nishikawa, H.3    Hayami, R.4    Oyake, D.5    Yabuki, Y.6    Fukuda, M.7    Ohta, T.8
  • 44
    • 77649339184 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BC3cXivFGru7k%3D 10.1016/j.biocel.2009.12.025 20060929
    • E Dizin I Irminger-Finger 2010 Int J Biochem Cell Biol 42 693 700 1:CAS:528:DC%2BC3cXivFGru7k%3D 10.1016/j.biocel.2009.12.025 20060929
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 693-700
    • Dizin, E.1    Irminger-Finger, I.2
  • 46
    • 0038743111 scopus 로고    scopus 로고
    • The role of the ubiquitination-proteasome pathway in breast cancer. Applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer
    • DOI 10.1186/bcr460
    • RZ Orlowski EC Dees 2003 Breast Cancer Res 5 1 7 1:CAS:528: DC%2BD3sXjtlCisL0%3D 10.1186/bcr460 12559038 (Pubitemid 36553571)
    • (2003) Breast Cancer Research , vol.5 , Issue.1 , pp. 1-7
    • Orlowski, R.Z.1    Dees, E.C.2
  • 47
    • 57149115173 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD1cXhsVGqtrvJ 10.1074/jbc.X800009200 18708349
    • A Varshavsky 2008 J Biol Chem 283 34469 34489 1:CAS:528: DC%2BD1cXhsVGqtrvJ 10.1074/jbc.X800009200 18708349
    • (2008) J Biol Chem , vol.283 , pp. 34469-34489
    • Varshavsky, A.1


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