New semidominant mutations that affect mouse development

Genesis (United States)

Volumn 40, Issue 2, 2004, Pages 109-117

  Bogani, Debora ^a   Warr, Nick ^a   Elms, Paul ^a   Davies, Jennifer ^a   Tymowska Lalanne, Zuzanna ^a   Goldsworthy, Michelle ^a   Cox, Roger D ^a   Keays, David A ^a,b   Flint, Jonathan ^b   Wilson, Valerie ^c   Nolan, Pat ^a   Arkell, Ruth ^a,d  

^a Mammalian Genetics Unit   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

Brachyury; ENU; Mouse gastrulation; Pax3; Wnt3a

Indexed keywords

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; HEART; HETEROZYGOSITY; HOMOZYGOSITY; LETHALITY; MALE; MOUSE; MUTAGENESIS; MUTANT; NEURAL CREST CELL; NEURAL TUBE DEFECT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; TAIL; TERATOLOGY;

EID: 8444232068     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20071     Document Type: Article

References (23)

1. Blake JA, Richardson JE, Bult CJ, Kadin JA, Eppig JT. 2003. MGD: the mouse genome database. Nucleic Acids Res 31:193-195.
2. Carrel T, Purandare SM, Harrison W, Elder F, Fox T, Casey B, Herman GE. 2000. The X-linked mouse mutation Bent tail is associated with a deletion of the Zic3 locus. Hum Mol Genet 9:1937-1942.
3. Carter M, Ulrich S, Oofuji Y, Williams DA, Ross ME. 1999. Crooked tail (Cd) models human folate-responsive neural tube defects. Hum Mol Genet 8:2199-2204.
4. Cattanach BM. 1987. A new curtailed mutation. Mouse News Lett 77:122.
5. Conlon FL, Sedgwick SG, Weston KM, Smith JC. 1996. Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122:2427-2435.
6. Elms P, Siggers P, Napper D, Greenfield A, Arkell R. 2003. Zic2 is required for neural crest formation and hind brain patterning during mouse development. Dev Biol 264:391-406.
7. 2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell 67:767-774.
8. Greco TL, Takada S, Newhouse MM, McMahon JA, McMahon AP, Camper SA. 1996. Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev 10:313-324.
9. Gruneberg H. 1958. Genetical studies on the skeleton of the mouse. XXIII. The development of brachury and anury. J Embryol Exp Morphol 6:424-443.
10. Herrmann B, Kispert A. 1994. The T genes in embryogenesis. Trends Genet 10:280-286.
11. Herrmann BG, Labeit S, Poustka A, King TR, Lehrach H. 1990. Cloning of the T gene required in mesoderm formation in the mouse. Nature 343:617-622.
12. Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25:444-447.
13. Huang E, Nocka K, Beier DR, Chu T-Y, Buck J, Lahm H-W, Wellner D, Leder P, Besmer P. 1990. The hematopoietic growth factor KL is encoded at the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63:225-233.
14. Klootwijk R, Franke B, van der Zee CE, de Boer RT, Wilms W, Hol FA, Mariman EC. 2000. A deletion encompassing Zic3 in bent tail, a mouse model for X-linked neural tube defects. Hum Mol Genet 9:1615-1622.
15. Major MH. 1955. Satin, sa. Mouse News Lett 12:47.
16. Neuhaus IM, Beier DR. 1998. Efficient localisation of mutations by interval haplotype analysis. Mamm Genome 9:150-154.
17. Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Klernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25:440-443.
18. Rinchik EM, Carpenter DA. 1999. N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations. Genetics 152:373-383.
19. Rosen B, Beddington R. 1994. Detection of mRNA in whole mounts of mouse embryos using digoxigenin riboprobes. Methods Mol Biol 28:201-208.
20. Russell WL. 1947. Splotch, a new mutation in the house mouse Mus musculus. Genetics 32:107.
21. Sarvella PA, Russell LB. 1956. Steel, a new dominant gene in the house mouse. J Hered 47:123-128.
22. Searle AG. 1966. Curtailed, a new dominant T-allele in the house mouse. Genet Res 7:86-95.
23. Wilkinson DG. 1992. Whole mount in situ hybridisation of vertebrate embryos. In: Wilkinson DG, editor. In situ hybridisation. Oxford: IRL Press, p 75-83.