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Volumn 6, Issue 2, 2011, Pages 129-142

A high-throughput multiplexed screening assay for optimizing serum-free differentiation protocols of human embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BASIC FIBROBLAST GROWTH FACTOR; BONE MORPHOGENETIC PROTEIN 4; CD34 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; HEPATOCYTE NUCLEAR FACTOR 3BETA; NERVE CELL ADHESION MOLECULE; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RED FLUORESCENT PROTEIN; SMALL INTERFERING RNA; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CER1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR MEOX1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX1; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 79951514003     PISSN: 18735061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scr.2010.11.001     Document Type: Article
Times cited : (9)

References (67)
  • 2
    • 74949122105 scopus 로고    scopus 로고
    • BMP4 regulates vascular progenitor development in human embryonic stem cells through a smad-dependent pathway
    • Bai H., Gao Y., Arzigian M., Wojchowski D.M., Wu W.S., Wang Z.Z. BMP4 regulates vascular progenitor development in human embryonic stem cells through a smad-dependent pathway. J. Cell. Biochem. 2010, 109:363-374.
    • (2010) J. Cell. Biochem. , vol.109 , pp. 363-374
    • Bai, H.1    Gao, Y.2    Arzigian, M.3    Wojchowski, D.M.4    Wu, W.S.5    Wang, Z.Z.6
  • 3
    • 50449205295 scopus 로고    scopus 로고
    • RNA interference screen to identify pathways that enhance or reduce nonviral gene transfer during lipofection
    • Barker G.A., Diamond S.L. RNA interference screen to identify pathways that enhance or reduce nonviral gene transfer during lipofection. Mol. Ther. 2008, 16:1602-1608.
    • (2008) Mol. Ther. , vol.16 , pp. 1602-1608
    • Barker, G.A.1    Diamond, S.L.2
  • 5
    • 34748921666 scopus 로고    scopus 로고
    • Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation
    • Carpenedo R.L., Sargent C.Y., McDevitt T.C. Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Stem Cells 2007, 25:2224-2234.
    • (2007) Stem Cells , vol.25 , pp. 2224-2234
    • Carpenedo, R.L.1    Sargent, C.Y.2    McDevitt, T.C.3
  • 7
    • 34548137338 scopus 로고    scopus 로고
    • Development of serum-free culture systems for human embryonic stem cells
    • Chase L.G., Firpo M.T. Development of serum-free culture systems for human embryonic stem cells. Curr. Opin. Chem. Biol. 2007, 11:367-372.
    • (2007) Curr. Opin. Chem. Biol. , vol.11 , pp. 367-372
    • Chase, L.G.1    Firpo, M.T.2
  • 10
    • 39349097787 scopus 로고    scopus 로고
    • Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors
    • Davis R.P., Ng E.S., Costa M., Mossman A.K., Sourris K., Elefanty A.G., Stanley E.G. Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors. Blood 2008, 111:1876-1884.
    • (2008) Blood , vol.111 , pp. 1876-1884
    • Davis, R.P.1    Ng, E.S.2    Costa, M.3    Mossman, A.K.4    Sourris, K.5    Elefanty, A.G.6    Stanley, E.G.7
  • 11
    • 44349152907 scopus 로고    scopus 로고
    • High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells
    • Desbordes S.C., Placantonakis D.G., Ciro A., Socci N.D., Lee G., Djaballah H., Studer L. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2008, 2:602-612.
    • (2008) Cell Stem Cell , vol.2 , pp. 602-612
    • Desbordes, S.C.1    Placantonakis, D.G.2    Ciro, A.3    Socci, N.D.4    Lee, G.5    Djaballah, H.6    Studer, L.7
  • 12
    • 30144432172 scopus 로고    scopus 로고
    • Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors
    • Ema M., Takahashi S., Rossant J. Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood 2006, 107:111-117.
    • (2006) Blood , vol.107 , pp. 111-117
    • Ema, M.1    Takahashi, S.2    Rossant, J.3
  • 15
    • 0041827036 scopus 로고    scopus 로고
    • Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation
    • Fehling H.J., Lacaud G., Kubo A., Kennedy M., Robertson S., Keller G., Kouskoff V. Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 2003, 130:4217-4227.
    • (2003) Development , vol.130 , pp. 4217-4227
    • Fehling, H.J.1    Lacaud, G.2    Kubo, A.3    Kennedy, M.4    Robertson, S.5    Keller, G.6    Kouskoff, V.7
  • 17
    • 33750936779 scopus 로고    scopus 로고
    • Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
    • Gadue P., Huber T.L., Paddison P.J., Keller G.M. Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc. Natl. Acad. Sci. USA 2006, 103:16806-16811.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16806-16811
    • Gadue, P.1    Huber, T.L.2    Paddison, P.J.3    Keller, G.M.4
  • 19
    • 1442311693 scopus 로고    scopus 로고
    • Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
    • Hay D.C., Sutherland L., Clark J., Burdon T. Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 2004, 22:225-235.
    • (2004) Stem Cells , vol.22 , pp. 225-235
    • Hay, D.C.1    Sutherland, L.2    Clark, J.3    Burdon, T.4
  • 21
    • 36849012549 scopus 로고    scopus 로고
    • Identification and targeting of the ROSA26 locus in human embryonic stem cells
    • Irion S., Luche H., Gadue P., Fehling H.J., Kennedy M., Keller G. Identification and targeting of the ROSA26 locus in human embryonic stem cells. Nat. Biotechnol. 2007, 25:1477-1482.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1477-1482
    • Irion, S.1    Luche, H.2    Gadue, P.3    Fehling, H.J.4    Kennedy, M.5    Keller, G.6
  • 22
    • 34547167658 scopus 로고    scopus 로고
    • Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference
    • Izumi N., Era T., Akimaru H., Yasunaga M., Nishikawa S. Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference. Stem Cells 2007, 25:1664-1674.
    • (2007) Stem Cells , vol.25 , pp. 1664-1674
    • Izumi, N.1    Era, T.2    Akimaru, H.3    Yasunaga, M.4    Nishikawa, S.5
  • 23
    • 0020997754 scopus 로고
    • Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells
    • Kannagi R., Cochran N.A., Ishigami F., Hakomori S., Andrews P.W., Knowles B.B., Solter D. Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J. 1983, 2:2355-2361.
    • (1983) EMBO J. , vol.2 , pp. 2355-2361
    • Kannagi, R.1    Cochran, N.A.2    Ishigami, F.3    Hakomori, S.4    Andrews, P.W.5    Knowles, B.B.6    Solter, D.7
  • 24
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • Kattman S.J., Huber T.L., Keller G.M. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev. Cell 2006, 11:723-732.
    • (2006) Dev. Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 25
    • 33947587879 scopus 로고    scopus 로고
    • Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures
    • Kennedy M., D'Souza S.L., Lynch-Kattman M., Schwantz S., Keller G. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood 2007, 109:2679-2687.
    • (2007) Blood , vol.109 , pp. 2679-2687
    • Kennedy, M.1    D'Souza, S.L.2    Lynch-Kattman, M.3    Schwantz, S.4    Keller, G.5
  • 26
    • 72849142382 scopus 로고    scopus 로고
    • Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures
    • King F.W., Ritner C., Liszewski W., Kwan H.C., Pedersen A., Leavitt A.D., Bernstein H.S. Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. Stem Cells Dev. 2009, 18:1441-1450.
    • (2009) Stem Cells Dev. , vol.18 , pp. 1441-1450
    • King, F.W.1    Ritner, C.2    Liszewski, W.3    Kwan, H.C.4    Pedersen, A.5    Leavitt, A.D.6    Bernstein, H.S.7
  • 27
    • 28944431989 scopus 로고    scopus 로고
    • A round-bottom 96-well polystyrene plate coated with 2-methacryloyloxyethyl phosphorylcholine as an effective tool for embryoid body formation
    • Koike M., Kurosawa H., Amano Y. A round-bottom 96-well polystyrene plate coated with 2-methacryloyloxyethyl phosphorylcholine as an effective tool for embryoid body formation. Cytotechnology 2005, 47:3-10.
    • (2005) Cytotechnology , vol.47 , pp. 3-10
    • Koike, M.1    Kurosawa, H.2    Amano, Y.3
  • 28
    • 36048953007 scopus 로고    scopus 로고
    • Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies
    • Koike M., Sakaki S., Amano Y., Kurosawa H. Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies. J. Biosci. Bioeng. 2007, 104:294-299.
    • (2007) J. Biosci. Bioeng. , vol.104 , pp. 294-299
    • Koike, M.1    Sakaki, S.2    Amano, Y.3    Kurosawa, H.4
  • 29
    • 0037023544 scopus 로고    scopus 로고
    • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
    • Kyba M., Perlingeiro R.C., Daley G.Q. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 2002, 109:29-37.
    • (2002) Cell , vol.109 , pp. 29-37
    • Kyba, M.1    Perlingeiro, R.C.2    Daley, G.Q.3
  • 30
    • 0028303227 scopus 로고
    • Polysialic acid of the neural cell adhesion molecule (N-CAM) is widely expressed during organogenesis in mesodermal and endodermal derivatives
    • Lackie P.M., Zuber C., Roth J. Polysialic acid of the neural cell adhesion molecule (N-CAM) is widely expressed during organogenesis in mesodermal and endodermal derivatives. Differentiation 1994, 57:119-131.
    • (1994) Differentiation , vol.57 , pp. 119-131
    • Lackie, P.M.1    Zuber, C.2    Roth, J.3
  • 31
    • 0025190642 scopus 로고
    • CNS stem cells express a new class of intermediate filament protein
    • Lendahl U., Zimmerman L.B., McKay R.D. CNS stem cells express a new class of intermediate filament protein. Cell 1990, 60:585-595.
    • (1990) Cell , vol.60 , pp. 585-595
    • Lendahl, U.1    Zimmerman, L.B.2    McKay, R.D.3
  • 34
    • 0033568470 scopus 로고    scopus 로고
    • Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4
    • McGrath K.E., Koniski A.D., Maltby K.M., McGann J.K., Palis J. Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev. Biol. 1999, 213:442-456.
    • (1999) Dev. Biol. , vol.213 , pp. 442-456
    • McGrath, K.E.1    Koniski, A.D.2    Maltby, K.M.3    McGann, J.K.4    Palis, J.5
  • 35
    • 0026698987 scopus 로고
    • Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas
    • Moller C.J., Christgau S., Williamson M.R., Madsen O.D., Niu Z.P., Bock E., Baekkeskov S. Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas. Mol. Endocrinol. 1992, 6:1332-1342.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1332-1342
    • Moller, C.J.1    Christgau, S.2    Williamson, M.R.3    Madsen, O.D.4    Niu, Z.P.5    Bock, E.6    Baekkeskov, S.7
  • 37
    • 58249095955 scopus 로고    scopus 로고
    • Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium
    • Nakanishi M., Kurisaki A., Hayashi Y., Warashina M., Ishiura S., Kusuda-Furue M., Asashima M. Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. FASEB J. 2009, 23:114-122.
    • (2009) FASEB J. , vol.23 , pp. 114-122
    • Nakanishi, M.1    Kurisaki, A.2    Hayashi, Y.3    Warashina, M.4    Ishiura, S.5    Kusuda-Furue, M.6    Asashima, M.7
  • 39
    • 23944454402 scopus 로고    scopus 로고
    • Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation
    • Ng E.S., Davis R.P., Azzola L., Stanley E.G., Elefanty A.G. Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood 2005, 106:1601-1603.
    • (2005) Blood , vol.106 , pp. 1601-1603
    • Ng, E.S.1    Davis, R.P.2    Azzola, L.3    Stanley, E.G.4    Elefanty, A.G.5
  • 40
    • 43149101280 scopus 로고    scopus 로고
    • A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies
    • Ng E.S., Davis R., Stanley E.G., Elefanty A.G. A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies. Nat. Protoc. 2008, 3:768-776.
    • (2008) Nat. Protoc. , vol.3 , pp. 768-776
    • Ng, E.S.1    Davis, R.2    Stanley, E.G.3    Elefanty, A.G.4
  • 41
    • 37549020639 scopus 로고    scopus 로고
    • Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood
    • Nostro M.C., Cheng X., Keller G.M., Gadue P. Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell 2008, 2:60-71.
    • (2008) Cell Stem Cell , vol.2 , pp. 60-71
    • Nostro, M.C.1    Cheng, X.2    Keller, G.M.3    Gadue, P.4
  • 42
    • 34547102737 scopus 로고    scopus 로고
    • Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage
    • Pankratz M.T., Li X.J., Lavaute T.M., Lyons E.A., Chen X., Zhang S.C. Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. Stem Cells 2007, 25:1511-1520.
    • (2007) Stem Cells , vol.25 , pp. 1511-1520
    • Pankratz, M.T.1    Li, X.J.2    Lavaute, T.M.3    Lyons, E.A.4    Chen, X.5    Zhang, S.C.6
  • 44
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • Park C., Afrikanova I., Chung Y.S., Zhang W.J., Arentson E., Fong Gh G., Rosendahl A., Choi K. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development 2004, 131:2749-2762.
    • (2004) Development , vol.131 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3    Zhang, W.J.4    Arentson, E.5    Fong Gh, G.6    Rosendahl, A.7    Choi, K.8
  • 46
    • 70350191753 scopus 로고    scopus 로고
    • Activin/nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity
    • Patani R., Compston A., Puddifoot C.A., Wyllie D.J., Hardingham G.E., Allen N.D., Chandran S. Activin/nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity. PLoS ONE [Electron. Resour.] 2009, 4:e7327.
    • (2009) PLoS ONE [Electron. Resour.] , vol.4
    • Patani, R.1    Compston, A.2    Puddifoot, C.A.3    Wyllie, D.J.4    Hardingham, G.E.5    Allen, N.D.6    Chandran, S.7
  • 47
    • 34748864145 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis
    • Pick M., Azzola L., Mossman A., Stanley E.G., Elefanty A.G. Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. Stem Cells 2007, 25:2206-2214.
    • (2007) Stem Cells , vol.25 , pp. 2206-2214
    • Pick, M.1    Azzola, L.2    Mossman, A.3    Stanley, E.G.4    Elefanty, A.G.5
  • 48
    • 34748888919 scopus 로고    scopus 로고
    • Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations
    • Pruszak J., Sonntag K.C., Aung M.H., Sanchez-Pernaute R., Isacson O. Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations. Stem Cells 2007, 25:2257-2268.
    • (2007) Stem Cells , vol.25 , pp. 2257-2268
    • Pruszak, J.1    Sonntag, K.C.2    Aung, M.H.3    Sanchez-Pernaute, R.4    Isacson, O.5
  • 49
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
    • Reubinoff B.E., Pera M.F., Fong C.Y., Trounson A., Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 2000, 18:399-404.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 50
    • 35549000259 scopus 로고    scopus 로고
    • Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types
    • Rodriguez R.T., Velkey J.M., Lutzko C., Seerke R., Kohn D.B., O'Shea K.S., Firpo M.T. Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Exp. Biol. Med. 2007, 232:1368-1380.
    • (2007) Exp. Biol. Med. , vol.232 , pp. 1368-1380
    • Rodriguez, R.T.1    Velkey, J.M.2    Lutzko, C.3    Seerke, R.4    Kohn, D.B.5    O'Shea, K.S.6    Firpo, M.T.7
  • 51
    • 33744997209 scopus 로고    scopus 로고
    • In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility
    • Sakurai H., Era T., Jakt L.M., Okada M., Nakai S., Nishikawa S., Nishikawa S. In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility. Stem Cells 2006, 24:575-586.
    • (2006) Stem Cells , vol.24 , pp. 575-586
    • Sakurai, H.1    Era, T.2    Jakt, L.M.3    Okada, M.4    Nakai, S.5    Nishikawa, S.6    Nishikawa, S.7
  • 52
    • 37349052866 scopus 로고    scopus 로고
    • Inhibition of activin/nodal signaling promotes specification of human embryonic stem cells into neuroectoderm
    • Smith J.R., Vallier L., Lupo G., Alexander M., Harris W.A., Pedersen R.A. Inhibition of activin/nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Dev. Biol. 2008, 313:107-117.
    • (2008) Dev. Biol. , vol.313 , pp. 107-117
    • Smith, J.R.1    Vallier, L.2    Lupo, G.3    Alexander, M.4    Harris, W.A.5    Pedersen, R.A.6
  • 54
    • 27644504639 scopus 로고    scopus 로고
    • Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture
    • Tada S., Era T., Furusawa C., Sakurai H., Nishikawa S., Kinoshita M., Nakao K., Chiba T., Nishikawa S. Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 2005, 132:4363-4374.
    • (2005) Development , vol.132 , pp. 4363-4374
    • Tada, S.1    Era, T.2    Furusawa, C.3    Sakurai, H.4    Nishikawa, S.5    Kinoshita, M.6    Nakao, K.7    Chiba, T.8    Nishikawa, S.9
  • 57
    • 70349878466 scopus 로고    scopus 로고
    • WNT and BMP signaling are both required for hematopoietic cell development from human ES cells
    • Wang Y., Nakayama N. WNT and BMP signaling are both required for hematopoietic cell development from human ES cells. Stem Cell Res. 2009, 3:113-125.
    • (2009) Stem Cell Res. , vol.3 , pp. 113-125
    • Wang, Y.1    Nakayama, N.2
  • 59
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L., Yuan X., Sharkis S.J. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 2006, 24:1476-1486.
    • (2006) Stem Cells , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 60
    • 34447525145 scopus 로고    scopus 로고
    • Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells
    • Xu Y., Mirmalek-Sani S.H., Lin F., Zhang J., Oreffo R.O. Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells. RNA 2007, 13:1179-1183.
    • (2007) RNA , vol.13 , pp. 1179-1183
    • Xu, Y.1    Mirmalek-Sani, S.H.2    Lin, F.3    Zhang, J.4    Oreffo, R.O.5
  • 62
    • 33646474117 scopus 로고    scopus 로고
    • Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
    • Yao S., Chen S., Clark J., Hao E., Beattie G.M., Hayek A., Ding S. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl. Acad. Sci. USA 2006, 103:6907-6912.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6907-6912
    • Yao, S.1    Chen, S.2    Clark, J.3    Hao, E.4    Beattie, G.M.5    Hayek, A.6    Ding, S.7
  • 65
    • 23044512574 scopus 로고    scopus 로고
    • Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development
    • Zambidis E.T., Peault B., Park T.S., Bunz F., Civin C.I. Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development. Blood 2005, 106:860-870.
    • (2005) Blood , vol.106 , pp. 860-870
    • Zambidis, E.T.1    Peault, B.2    Park, T.S.3    Bunz, F.4    Civin, C.I.5
  • 67
    • 55949089929 scopus 로고    scopus 로고
    • Lipofectamine RNAiMAX: an efficient siRNA transfection reagent in human embryonic stem cells
    • Zhao M., Yang H., Jiang X., Zhou W., Zhu B., Zeng Y., Yao K., Ren C. Lipofectamine RNAiMAX: an efficient siRNA transfection reagent in human embryonic stem cells. Mol. Biotechnol. 2008, 40:19-26.
    • (2008) Mol. Biotechnol. , vol.40 , pp. 19-26
    • Zhao, M.1    Yang, H.2    Jiang, X.3    Zhou, W.4    Zhu, B.5    Zeng, Y.6    Yao, K.7    Ren, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.