MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas: Their roles as prognostic indicators

Cancer

Volumn 92, Issue 6, 2001, Pages 1427-1434

  Lee, Hye Seung ^a   Lee, Hyeon Kook ^a   Kim, Hee Sung ^a,b   Yang, Han Kwang ^a   Kim, Yong Il ^a   Kim, Woo Ho ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Gastric adenoma; Gastric carcinoma; MUC1; MUC2; MUC5AC; MUC6

Indexed keywords

MUCIN; MUCIN 1; MUCIN 2; MUCIN 5AC; MUCIN 6; PROTEIN P53; UNCLASSIFIED DRUG;

ADENOMA; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; STOMACH CARCINOMA; TISSUE DISTRIBUTION;

ADENOMA; ANTIGENS; CA-15-3 ANTIGEN; CARCINOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MUCINS; PROGNOSIS; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035883673     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20010915)92:6<1427::AID-CNCR1466>3.0.CO;2-L     Document Type: Article

References (34)

1. Mucin glycoproteins in neoplasia
2. Expression of mucin antigens in human cancers and its relationship with malignancy potential
3. Mucins in normal and neoplastic human gastrointestinal tissues
4. Mucin gene expression in normal, preneoplastic, and neoplastic human gastric epithelium
5. Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma
6. Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody
7. Differential apomucin expression in normal and neoplastic human gastrointestinal tissues
8. Expression of a peptide epitope of the colonic mucin MUC2 in precursor lesions of gastric carcinoma
9. Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression
10. MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach
11. Correlation of the immunohistochemical reactivity of mucin peptide cores MUC1 and MUC2 with the histopathological subtype and prognosis of gastric carcinomas
12. Mucin antigen expression in gastric carcinomas of young and old adults
13. Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression
14. Patterns of expression of trefoil peptides and mucins in gastric polyps with and without malignant transformation
15. Expression of MUC1 and MUC2 mucins in gastric carcinomas: Its relationship with the prognosis of the patients
16. Widespread p53 overexpression in human malignant tumors
17. Clinical implications of the p53 tumor-suppressor gene
18. Expression of p53 protein in gastric carcinomas. Association with histologic type and prognosis
19. p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type
20. Differential p53 protein expression in stomach adenomas of gastric intestinal phenotypes: Possible sequences of p53 alteration in stomach carcinogenesis
21. Suppression of cellular aggregation by high levels of episialin
22. Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components
23. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1
24. The breast mucin MUC1 as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer
25. Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation
26. Macrophage-tumour cell interactions: Identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin
27. Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction
28. Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2
29. p53 in tumour pathology: Can we trust immunohistochemistry?
30. p53 gene point mutations in relation to p53 nuclear protein accumulation in colorectal cancers
31. Genetic basis for p53 over-expression in human breast cancer
32. Long-term follow-up on gastric adenoma and its relation to gastric protruded carcinoma
33. Gastric polyps: A histogenetic classification and its relation to carcinoma
34. Microsatellite instability in precancerous lesions and adenocarcinomas of the stomach