Lidocaine suppresses the increased extracellular signalregulated kinase/cyclic AMP response element-binding protein pathway and pro-inflammatory cytokines in a neuropathic pain model of rats

European Journal of Anaesthesiology

Volumn 28, Issue 2, 2011, Pages 106-111

  Joo, Jin D ^b   Choi, Jin W ^b   In, Jang H ^b   Jung, Hong S ^b   Lee, Jung A ^b   Kim, Yong S ^b   Kim, Dae W ^b   Yeom, Je H ^b   Shin, Eun Y ^a   Jeon, Yeon S ^b  

^a Research Institute of Medical Science   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Cyclic AMP response element binding protein; Extracellular signal regulated kinase 1 2; Lidocaine; Neuropathic pain; Pro inflammatory cytokine

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIDOCAINE; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOBLOTTING; MALE; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOTIC PUMP; OUTCOME ASSESSMENT; PAIN ASSESSMENT; PAIN THRESHOLD; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHAM PROCEDURE; SIGNAL TRANSDUCTION; SPINAL NERVE; SPRAGUE DAWLEY RAT;

ANESTHETICS, LOCAL; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; LIDOCAINE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURALGIA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 79951478665     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e32834050fb     Document Type: Article

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