Local anesthetics reduce mortality and protect against renal and hepatic dysfunction in murine septic peritonitis

Anesthesiology

Volumn 101, Issue 4, 2004, Pages 902-911

  Gallos, George ^a   Jones, Dean R ^a   Nasr, Samih H ^a,b   Emala, Charles W ^a   Lee, H Thomas ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BUPIVACAINE; CHEMOKINE; CREATININE; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; LIDOCAINE; LOCAL ANESTHETIC AGENT; MESSENGER RNA; MYELOPEROXIDASE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; INFLAMMATION; KIDNEY CORTEX; KIDNEY DYSFUNCTION; KIDNEY INJURY; LIVER DYSFUNCTION; LIVER INJURY; LOCAL ANESTHESIA; MALE; MORTALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOTIC MINIPUMP; PERITONITIS; PRIORITY JOURNAL; SEPSIS; SEPTIC PERITONITIS; SURVIVAL RATE;

ANESTHETICS, LOCAL; ANIMALS; APOPTOSIS; CHEMOKINES; KIDNEY; LIVER; MALE; MICE; MICE, INBRED C57BL; PERITONITIS; PEROXIDASE; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644261782     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200410000-00015     Document Type: Article

References (40)

1. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR: Epidemiology of severe sepsis in the United States: Analysis of incidence, out-come, and associated costs of care. Crit Care Med 2001; 29:1303-10
2. Preise H, Bruckner UB, Spiegel HU: Animal models of sepsis. J Invest Surg 2001; 14:195-212
3. Ebong S, Call D, Nemzek J, Bolgos G, Newcomb D, Remick D: Immuno-pathologic alterations in murine models of sepsis of increasing severity. Infect Immun 1999; 67:6603-10
4. Miyaji T, Hu X, Yuen PS, Muramatsu Y, Iyer S, Hewitt SM, Star RA: Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Kidney Int 2003; 64:1620-31
5. Cohen J: The immunopathogenesis of sepsis. Nature 2002; 420:885-91
6. Strohm C, Barancik T, Bruhl ML, Kilian SA, Schaper W: Inhibition of the ER-kinase cascade by PD98059 and UO126 counteracts ischemic preconditioning in pig myocardium. J Cardiovasc Pharmacol 2000; 36:218-29
7. Lee R, Nitta T, Schmid RA, Schuessler RB, Harris KM, Gay WA Jr: Retrograde infusion of lidocaine or L-arginine before reperfusion reduces myocardial infarct size. Ann Thorac Surg 1998; 65:1353-9
8. Das KC, Misra HP: Prevention of reperfusion lung injury by lidocaine in isolated rat lung ventilated with higher oxygen levels. J Postgrad Med 2003; 49: 17-20
9. Schmid RA, Yamashita M, Ando K, Tanaka Y, Cooper JD, Patterson GA: Lidocaine reduces reperfusion injury and neutrophil migration in canine lung allografts. Ann Thorac Surg 1996; 61: 949-55
10. Tomori H, Shiraishi M, Koga H, Toure M, Taira K, Higa T, Okuhama Y, Hiroyasu S, Muto Y: Protective effects of lidocaine in hepatic ischemia/reperfusion injury in vitro. Transplant Proc 1998; 30: 3740-2
11. Hollmann MW, Durieux ME: Local anesthetics and the inflammatory response: A new therapeutic indication? ANESTHESIOLOGY 2000; 93: 858-75
12. Lee HT, Krichevsky IE, Xu H, Ota-Setlik A, D'Agati VD, Emala CW: Local anesthetics worsen renal function after ischemia-reperfusion injury in rats. Am J Physiol Renal Physiol 2004; 286:F111-9
13. Walley KR, Lukacs NW, Standiford TJ, Strieter RM, Kunkel SL: Balance of inflammatory cytokines related to severity and mortality of murine sepsis. Infect Immun 1996; 64:4733-8
14. Heinegard D, Tiderstrom G: Determination of serum creatinine by a direct colorimetric method. Clin Chim Acta 1973; 43:305-10
15. Jablonski P, Howden BO, Rae DA, Birrel CS, Marshall VC, Tange J: An experimental model for assessment of renal recovery from warm ischemia. Transplantation 1983: 35:198-204
16. Lee HT, Gallos G, Nasr SH, Emala CW: Al adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2004; 15:102-11
17. Ysebaert DK, De Greef KE, Vercauteren SR, Ghielli M, Verpooten GA, Eyskens EJ, De Broe ME: Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury. Nephrol Dial Transplant 2000; 15:1562-74
18. Dumitru CD, Ceci JD, Tsatsanis C, Kontoyiannis D, Stamatakis K, Lin JH, Patriotis C, Jenkins NA, Copeland NG, Kollias G, Tsichlis PN: TNF-alpha induction by LPS is regulated posttranscriptionally via a Tp12/ERK-dependent pathway. Cell 2000; 103:1071-83
19. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101:1644-55
20. Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348:138-50
21. Remick D, Manohar P, Bolgos G, Rodriguez J, Moldawer L, Wollenberg G: Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture. Shock 1995; 4:89-95
22. Gold JA, Parsey M, Hoshino Y, Hoshino S, Nolan A, Yee H, Tse DB, Weiden MD: CD40 contributes to lethality in acute sepsis: In vivo role for CD40 in innate immunity. Infect Immun 2003; 71:3521-8
23. Van den BG, Wouters P, Weckers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R: Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345:1359-67
24. Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, Capellier G, Cohen Y, Azoulay E, Troche G, Chaumet-Riffaut P, Bellissant E: Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288:862-71
25. Vincent JL, Angus DC, Artigas A, Kalil A. Basson BR, Jamal HH, Johnson G III, Bernard GR: Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med 2003; 31:834-40
26. Takao Y, Mikawa K, Nishina K, Maekawa N. Obara H: Lidocaine attenuates hyperoxic lung injury in rabbits. Acta Anaesthesiol Scand 1996; 40:318-25
27. Sinclair R, Eriksson AS, Gretzer C, Cassuto J, Thomsen P: Inhibitory effects of amide local anaesthetics on stimulus-induced human leukocyte metabolic activation, LTB4 release and IL-1 secretion in vitro. Acta Anaesthesiol Scand 1993; 37:159-65
28. Li CY, Tsai CS, Hsu PC, Chueh SH, Wong CS, Ho ST: Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: Possible mechanisms for its effect on inflammation. Anesth Analg 2003; 97:1312-6
29. Hammer R, Dahlgren C, Stendahl O: Inhibition of human leukocyte metabolism and random mobility by local anaesthesia. Acta Anaesthesiol Scand 1985; 29:520-3
30. Tuman KJ, McCarthy RJ, March RJ, DeLaria GA, Patel RV, Ivankovich AD: Effects of epidural anesthesia and analgesia on coagulation and outcome after major vascular surgery. Anesth Analg 1991; 73:696-704
31. Cunningham PN, Dyanov HM, Park P, Wang J, Newell KA, Quigg RJ: Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol 2002; 168:5817-23
32. Leon LR, White AA, Kluger MJ: Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice. Am J Physiol 1998; 275:R269-R277
33. Mercer-Jones MA, Shrotri MS, Peyton JC, Remick DG, Cheadle WG: Neutrophil sequestration in liver and lung is differentially regulated by C-X-C chemokines during experimental peritonitis. Inflammation 1999; 23:305-19
34. Maier S, Emmanuilidis K, Entleutner M, Zantl N, Werner M, Pfeffer K, Heidecke CD: Massive chemokine transcription in acute renal failure due to polymicrobial sepsis. Shock 2000; 14:187-92
35. Remick DG, Call DR, Ebong SJ, Newcomb DE, Nybom P, Nemzek JA, Bolgos GE: Combination immunotherapy with soluble tumor necrosis factor receptors plus interleukin 1 receptor antagonist decreases sepsis mortality. Crit Care Med 2001; 29:473-81
36. Viedt C, Dechend R, Fei J, Hansch GM, Kreuzer J, Orth SR: MCP-1 induces inflammatory activation of human tubular epithelial cells: Involvement of the transcription factors, nuclear factor-kappaB and activating protein-1. J Am Soc Nephrol 2002; 13:1534-47
37. Daemen MA, de Vries B, Buurman WA: Apoptosis and inflammation in renal reperfusion injury. Transplantation 2002; 73:1693-700
38. Daemen MA, van't Veer C, Denecker G, Heemskerk VH, Wolfs TG, Clauss M, Vandenabeele P, Buurman WA: Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999; 104:541-9
39. Jo SK, Cha DR, Cho WY, Kim HK, Chang KH, Yun SY, Won NH: Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells. Nephron 2002; 91:406-15
40. Wan L, Bellomo R, Di Giantomasso D, Ronco C: The pathogenesis of septic acute renal failure. Curr Opin Crit Care 2003; 9:496-502