-
1
-
-
19644399531
-
Production of recombinant proteins by vaccinia virus in a microcarrier based mammalian cell perfusion bioreactor
-
Bleckwenn NA, Golding H, Bentley WE, Shiloach J. Production of recombinant proteins by vaccinia virus in a microcarrier based mammalian cell perfusion bioreactor. Biotechnol. Bioeng. 2005; 90: 663-674.
-
(2005)
Biotechnol. Bioeng.
, vol.90
, pp. 663-674
-
-
Bleckwenn, N.A.1
Golding, H.2
Bentley, W.E.3
Shiloach, J.4
-
2
-
-
73249150586
-
Growth behaviour of number distributed adherent MDCK cells in microcarrier cultures
-
Bock A, Möhler L, Sann H, Schulze-Horsel J, Genzel Y, Reichl U. Growth behaviour of number distributed adherent MDCK cells in microcarrier cultures. Biotechnol. Progr. 2009; 29: 1717-1731.
-
(2009)
Biotechnol. Progr.
, vol.29
, pp. 1717-1731
-
-
Bock, A.1
Möhler, L.2
Sann, H.3
Schulze-Horsel, J.4
Genzel, Y.5
Reichl, U.6
-
3
-
-
0004221581
-
Virology. A Laboratory Manual
-
San Diego: Academic Press.
-
Burleson F, Wiedbrauk C. 1992. Virology. A Laboratory Manual. San Diego: Academic Press.
-
(1992)
-
-
Burleson, F.1
Wiedbrauk, C.2
-
4
-
-
33747362656
-
Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by mammalian cell systems
-
Butler M. Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by mammalian cell systems. Cytotechnology. 2006; 50: 57-76.
-
(2006)
Cytotechnology.
, vol.50
, pp. 57-76
-
-
Butler, M.1
-
6
-
-
0036360493
-
Advances in Biochemical Engineering/Biotechnology
-
In: Scheper T, editor. Berlin, Heidelberg: Springer-Verlag; -
-
Castilho L, Medronho R. Cell retention devices for suspended-cell perfusion cultures. In: Scheper T, editor. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer-Verlag; 2002: 129-169.
-
(2002)
Cell retention devices for suspended-cell perfusion cultures
, pp. 129-169
-
-
Castilho, L.1
Medronho, R.2
-
7
-
-
0034610517
-
Perfusion culture of baculovirus-infected BTI-Tn-5B1-4 insect cells: a method to restore cell-specific beta-trace glycoprotein productivity at high cell density
-
Chico E, Jager V. Perfusion culture of baculovirus-infected BTI-Tn-5B1-4 insect cells: a method to restore cell-specific beta-trace glycoprotein productivity at high cell density. Biotechnol. Bioeng. 2000; 70: 574-586.
-
(2000)
Biotechnol. Bioeng.
, vol.70
, pp. 574-586
-
-
Chico, E.1
Jager, V.2
-
8
-
-
50549164568
-
Plaque formation by influenza A2 virus in monkey kidney cells
-
Choppin PW. Plaque formation by influenza A2 virus in monkey kidney cells. Virology. 1962; 18: 332-334.
-
(1962)
Virology.
, vol.18
, pp. 332-334
-
-
Choppin, P.W.1
-
9
-
-
13544275712
-
A perfusion culture system using a stirred ceramic membrane reactor for hyperproduction of IgG(2a) monoclonal antibody by hybridoma cells
-
Dong H, Tang YJ, Ohashi R, Hamel JFP. A perfusion culture system using a stirred ceramic membrane reactor for hyperproduction of IgG(2a) monoclonal antibody by hybridoma cells. Biotechnol. Progr. 2005; 21: 140-147.
-
(2005)
Biotechnol. Progr.
, vol.21
, pp. 140-147
-
-
Dong, H.1
Tang, Y.J.2
Ohashi, R.3
Hamel, J.F.P.4
-
10
-
-
0242557474
-
Optimization and control of perfusion cultures using a viable cell probe and cell specific perfusion rates
-
Dowd JE, Jubb A, Kwok KE, Piret JM. Optimization and control of perfusion cultures using a viable cell probe and cell specific perfusion rates. Cytotechnology. 2003; 42: 35-45.
-
(2003)
Cytotechnology.
, vol.42
, pp. 35-45
-
-
Dowd, J.E.1
Jubb, A.2
Kwok, K.E.3
Piret, J.M.4
-
11
-
-
2442437845
-
Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture
-
Genzel Y, Behrendt I, Konig S, Sann H, Reichl U. Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture. Vaccine. 2004; 22: 2202-2208.
-
(2004)
Vaccine.
, vol.22
, pp. 2202-2208
-
-
Genzel, Y.1
Behrendt, I.2
Konig, S.3
Sann, H.4
Reichl, U.5
-
12
-
-
33746809465
-
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media
-
Genzel Y, Olmer RM, Schafer B, Reichl U. Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media. Vaccine. 2006; 24: 6074-6087.
-
(2006)
Vaccine.
, vol.24
, pp. 6074-6087
-
-
Genzel, Y.1
Olmer, R.M.2
Schafer, B.3
Reichl, U.4
-
13
-
-
73849115748
-
Continuous cell lines as a production system for influenza vaccines
-
Genzel Y, Reichl U. Continuous cell lines as a production system for influenza vaccines. Exp Rev Vaccines. 2009; 8: 1681-1692.
-
(2009)
Exp Rev Vaccines.
, vol.8
, pp. 1681-1692
-
-
Genzel, Y.1
Reichl, U.2
-
14
-
-
13544268489
-
Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells
-
Genzel Y, Ritter JB, Konig S, Alt R, Reichl U. Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells. Biotechnol. Progr. 2005; 21: 58-69.
-
(2005)
Biotechnol. Progr.
, vol.21
, pp. 58-69
-
-
Genzel, Y.1
Ritter, J.B.2
Konig, S.3
Alt, R.4
Reichl, U.5
-
15
-
-
9844226221
-
Serial propagation of influenza B (Lee) virus in a transmissible line of canine kidney cells
-
Green IJ. Serial propagation of influenza B (Lee) virus in a transmissible line of canine kidney cells. Science. 1962; 138: 42-43.
-
(1962)
Science.
, vol.138
, pp. 42-43
-
-
Green, I.J.1
-
16
-
-
2942618534
-
Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures
-
Henry O, Dormond E, Perrier M, Kamen A. Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnol. Bioeng. 2004; 86: 765-774.
-
(2004)
Biotechnol. Bioeng.
, vol.86
, pp. 765-774
-
-
Henry, O.1
Dormond, E.2
Perrier, M.3
Kamen, A.4
-
17
-
-
0014661176
-
Spin filter culture-propagation of mammalian cells in suspension
-
Himmelfarb P, Thayer PS, Martin HE. Spin filter culture-propagation of mammalian cells in suspension. Science 1969; 164(3879): 555-557.
-
(1969)
Science
, vol.164
, Issue.3879
, pp. 555-557
-
-
Himmelfarb, P.1
Thayer, P.S.2
Martin, H.E.3
-
18
-
-
0025516236
-
High cell-density suspension-culture of mammalian anchorage independent cells-oxygen-transfer by gas sparging and defoaming with a hydrophobic net
-
Ishida M, Haga R, Nishimura N, Matuzaki H, Nakano R. High cell-density suspension-culture of mammalian anchorage independent cells-oxygen-transfer by gas sparging and defoaming with a hydrophobic net. Cytotechnology. 1990; 4: 215-225.
-
(1990)
Cytotechnology.
, vol.4
, pp. 215-225
-
-
Ishida, M.1
Haga, R.2
Nishimura, N.3
Matuzaki, H.4
Nakano, R.5
-
19
-
-
33947611187
-
Purification of cell culture-derived human influenza a virus by size-exclusion and anion-exchange chromatography
-
Kalbfuss B, Wolff M, Morenweiser R, Reichl U. Purification of cell culture-derived human influenza a virus by size-exclusion and anion-exchange chromatography. Biotechnol. Bioeng. 2007; 96: 932-944.
-
(2007)
Biotechnol. Bioeng.
, vol.96
, pp. 932-944
-
-
Kalbfuss, B.1
Wolff, M.2
Morenweiser, R.3
Reichl, U.4
-
20
-
-
0037161623
-
Evaluation of various serum and animal protein free media for the production of a veterinary rabies vaccine in BHK-21 cells
-
Kallel H, Jouini A, Majoul S, Rourou S. Evaluation of various serum and animal protein free media for the production of a veterinary rabies vaccine in BHK-21 cells. J. Biotechnol. 2002; 95: 195-204.
-
(2002)
J. Biotechnol.
, vol.95
, pp. 195-204
-
-
Kallel, H.1
Jouini, A.2
Majoul, S.3
Rourou, S.4
-
21
-
-
0031761413
-
Temperature significantly affects retroviral vector production and deactivation rates, and thereby determines retroviral titers
-
Lee GM, Choi JH, Jun SC, Palsson BO. Temperature significantly affects retroviral vector production and deactivation rates, and thereby determines retroviral titers. Bioprocess Eng. 1998; 19: 343-349.
-
(1998)
Bioprocess Eng.
, vol.19
, pp. 343-349
-
-
Lee, G.M.1
Choi, J.H.2
Jun, S.C.3
Palsson, B.O.4
-
22
-
-
0014586350
-
Antigenicity of influenza vaccine from bovine cell cultures
-
Leiderman E, Mogabgab WJ. Antigenicity of influenza vaccine from bovine cell cultures. Appl. Microbiol. 1969; 18: 596-600.
-
(1969)
Appl. Microbiol.
, vol.18
, pp. 596-600
-
-
Leiderman, E.1
Mogabgab, W.J.2
-
23
-
-
0026832885
-
Quantification of cell-culture factors affecting recombinant protein yields in baculovirus-infected insect cells
-
Lindsay DA, Betenbaugh MJ. Quantification of cell-culture factors affecting recombinant protein yields in baculovirus-infected insect cells. Biotechnol. Bioeng. 1992; 39: 614-618.
-
(1992)
Biotechnol. Bioeng.
, vol.39
, pp. 614-618
-
-
Lindsay, D.A.1
Betenbaugh, M.J.2
-
24
-
-
0032899430
-
The role of the cell cycle in determining gene expression and productivity in CHO cells
-
Lloyd DR, Leelavatcharamas V, Emery AN, Al-Rubeai M. The role of the cell cycle in determining gene expression and productivity in CHO cells. Cytotechnology. 1999; 30: 49-57.
-
(1999)
Cytotechnology.
, vol.30
, pp. 49-57
-
-
Lloyd, D.R.1
Leelavatcharamas, V.2
Emery, A.N.3
Al-Rubeai, M.4
-
25
-
-
67650430190
-
New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation
-
Lohr V, Rath A, Genzel Y, Jordan I, Sandig V, Reichl U. New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation. Vaccine. 2009; 27: 4975-4982.
-
(2009)
Vaccine.
, vol.27
, pp. 4975-4982
-
-
Lohr, V.1
Rath, A.2
Genzel, Y.3
Jordan, I.4
Sandig, V.5
Reichl, U.6
-
26
-
-
0141616435
-
Virus-like particle production at low multiplicities of infection with the baculovirus insect cell system
-
Maranga L, Brazao TF, Carrondo MJT. Virus-like particle production at low multiplicities of infection with the baculovirus insect cell system. Biotechnol Bioeng. 2003; 84: 245-253.
-
(2003)
Biotechnol Bioeng.
, vol.84
, pp. 245-253
-
-
Maranga, L.1
Brazao, T.F.2
Carrondo, M.J.T.3
-
27
-
-
58049145133
-
Inactivated influenza vaccines prepared in cell culture
-
In: Brown F, Robertson JS, Schild GC, Wood JM, editors. Basel, Karger: Dev. Biol. Stand.
-
Merten OW, Manuguerra J-C, Hannoun C, van der Werf S. Production of influenza virus in serum-free mammalian cell cultures. In: Brown F, Robertson JS, Schild GC, Wood JM, editors. Inactivated influenza vaccines prepared in cell culture. Basel, Karger: Dev. Biol. Stand.; 1999; 98: 23-37.
-
(1999)
Production of influenza virus in serum-free mammalian cell cultures
, vol.98
, pp. 23-37
-
-
Merten, O.W.1
Manuguerra, J.-C.2
Hannoun, C.3
van der Werf, S.4
-
28
-
-
0343443436
-
The Utilization of Carbohydrates by Animal Cells
-
In: Morgan M, editor. New York: Plenum Press.
-
Morgan M, Faik P. In: Morgan M, editor. The Utilization of Carbohydrates by Animal Cells. New York: Plenum Press; 1986.
-
(1986)
-
-
Morgan, M.1
Faik, P.2
-
29
-
-
0028786753
-
An experimental rabies vaccine produced with a new BHK-21 suspension cell-culture process-use of serum-free medium and perfusion-reactor system
-
Perrin P, Madhusudana S, Gontierjallet C, Petres S, Tordo N, Merten OW. An experimental rabies vaccine produced with a new BHK-21 suspension cell-culture process-use of serum-free medium and perfusion-reactor system. Vaccine. 1995; 13: 1244-1250.
-
(1995)
Vaccine.
, vol.13
, pp. 1244-1250
-
-
Perrin, P.1
Madhusudana, S.2
Gontierjallet, C.3
Petres, S.4
Tordo, N.5
Merten, O.W.6
-
30
-
-
48949102557
-
Interpretation data for bioreactors for the increase of scale of a microcarrier-based virus production process
-
Pohlscheidt M, Bodeker B, Langer U, Apeler H, Horlein HD, Rubsamen-Waigmann H, Reichl U, Henzler HJ. Interpretation data for bioreactors for the increase of scale of a microcarrier-based virus production process. Chemie Ingenieur Technik. 2008; 80: 821-830.
-
(2008)
Chemie Ingenieur Technik.
, vol.80
, pp. 821-830
-
-
Pohlscheidt, M.1
Bodeker, B.2
Langer, U.3
Apeler, H.4
Horlein, H.D.5
Rubsamen-Waigmann, H.6
Reichl, U.7
Henzler, H.J.8
-
31
-
-
0242642143
-
Kinetics and metabolic specificities of Vero cells in bioreactor cultures with serum-free medium
-
Quesney S, Marc A, Gerdil C, Gimenez C, Marvel J, Richard Y, Meignier B. Kinetics and metabolic specificities of Vero cells in bioreactor cultures with serum-free medium. Cytotechnology. 2003; 42: 1-11.
-
(2003)
Cytotechnology.
, vol.42
, pp. 1-11
-
-
Quesney, S.1
Marc, A.2
Gerdil, C.3
Gimenez, C.4
Marvel, J.5
Richard, Y.6
Meignier, B.7
-
32
-
-
44649161769
-
Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine production
-
Schulze-Horsel J, Genzel Y, Reichl U. Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine production. BMC Biotechnol. 2008; 8: 45.
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 45
-
-
Schulze-Horsel, J.1
Genzel, Y.2
Reichl, U.3
-
33
-
-
64449088759
-
Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production-flow cytometry and mathematical modeling
-
Schulze-Horsel J, Schulze M, Agalaridis G, Genzel Y, Reichl U. Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production-flow cytometry and mathematical modeling. Vaccine. 2009; 27: 2712-2722.
-
(2009)
Vaccine.
, vol.27
, pp. 2712-2722
-
-
Schulze-Horsel, J.1
Schulze, M.2
Agalaridis, G.3
Genzel, Y.4
Reichl, U.5
-
34
-
-
79851493251
-
Cells and Culture
-
In: Noll T, editor. Dresden, Germany: Springer.
-
Schulze-Horsel J, Schulze M, Genzel Y, Reichl U. In: Noll T, editor. Cells and Culture. Dresden, Germany: Springer; 2007.
-
(2007)
-
-
Schulze-Horsel, J.1
Schulze, M.2
Genzel, Y.3
Reichl, U.4
-
35
-
-
85047677838
-
Improving an on-line feeding strategy for fed-batch cultures of hybridoma cells by dialysis and 'Nutrient-Split'-feeding
-
Schwabe JO, Portner R, Markl H. Improving an on-line feeding strategy for fed-batch cultures of hybridoma cells by dialysis and 'Nutrient-Split'-feeding. Bioprocess Eng. 1999; 20: 475-484.
-
(1999)
Bioprocess Eng.
, vol.20
, pp. 475-484
-
-
Schwabe, J.O.1
Portner, R.2
Markl, H.3
-
36
-
-
67649625767
-
Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin
-
Schwarzer J, Rapp E, Hennig R, Genzel Y, Jordan I, Sandig V, Reichl U. Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin. Vaccine. 2009; 27: 4325-4336.
-
(2009)
Vaccine.
, vol.27
, pp. 4325-4336
-
-
Schwarzer, J.1
Rapp, E.2
Hennig, R.3
Genzel, Y.4
Jordan, I.5
Sandig, V.6
Reichl, U.7
-
37
-
-
56849090276
-
N-glycan analysis by CGE-LIF: profiling influenza A virus hemagglutinin N-glycosylation during vaccine production
-
Schwarzer J, Rapp E, Reichl U. N-glycan analysis by CGE-LIF: profiling influenza A virus hemagglutinin N-glycosylation during vaccine production. Electrophoresis. 2008; 29: 4203-4214.
-
(2008)
Electrophoresis.
, vol.29
, pp. 4203-4214
-
-
Schwarzer, J.1
Rapp, E.2
Reichl, U.3
-
38
-
-
8144221045
-
Acoustic cell filter: a proven cell retention technology for perfusion of animal cell cultures
-
Shirgaonkar IZ, Lanthier S, Kamen A. Acoustic cell filter: a proven cell retention technology for perfusion of animal cell cultures. Biotechnol. Adv. 2004; 22: 433-444.
-
(2004)
Biotechnol. Adv.
, vol.22
, pp. 433-444
-
-
Shirgaonkar, I.Z.1
Lanthier, S.2
Kamen, A.3
-
39
-
-
0035858122
-
Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains
-
Tree JA, Richardson C, Fooks AR, Clegg JC, Looby D. Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains. Vaccine. 2001; 19: 3444-3450.
-
(2001)
Vaccine.
, vol.19
, pp. 3444-3450
-
-
Tree, J.A.1
Richardson, C.2
Fooks, A.R.3
Clegg, J.C.4
Looby, D.5
-
40
-
-
0037572331
-
Potential of cell retention techniques for large-scale high-density perfusion culture of suspended mammalian cells
-
Voisard D, Meuwly F, Ruffieux PA, Baer G, Kadouri A. Potential of cell retention techniques for large-scale high-density perfusion culture of suspended mammalian cells. Biotechnol. Bioeng. 2003; 82: 751-765.
-
(2003)
Biotechnol. Bioeng.
, vol.82
, pp. 751-765
-
-
Voisard, D.1
Meuwly, F.2
Ruffieux, P.A.3
Baer, G.4
Kadouri, A.5
-
41
-
-
13344284632
-
Low multiplicity infection of insect cells with a recombinant baculovirus: the cell yield concept
-
Wong KTK, Peter CH, Greenfield PF, Reid S, Nielsen LK. Low multiplicity infection of insect cells with a recombinant baculovirus: the cell yield concept. Biotechnol. Bioeng. 1996; 49: 659-666.
-
(1996)
Biotechnol. Bioeng.
, vol.49
, pp. 659-666
-
-
Wong, K.T.K.1
Peter, C.H.2
Greenfield, P.F.3
Reid, S.4
Nielsen, L.K.5
-
42
-
-
0020070915
-
Inhibition of Autographa californica nuclear polyhedrosis virus replication in high-density Trichoplusia ni cell cultures
-
Wood HA, Johnston LB, Burand JP. Inhibition of Autographa californica nuclear polyhedrosis virus replication in high-density Trichoplusia ni cell cultures. Virology 1982; 119: 245-254.
-
(1982)
Virology
, vol.119
, pp. 245-254
-
-
Wood, H.A.1
Johnston, L.B.2
Burand, J.P.3
-
43
-
-
0028693147
-
Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal-cells in bioreactor
-
Xie LZ, Wang DIC. Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal-cells in bioreactor. Cytotechnology. 1994; 15: 17-29.
-
(1994)
Cytotechnology.
, vol.15
, pp. 17-29
-
-
Xie, L.Z.1
Wang, D.I.C.2
-
44
-
-
33747341098
-
The importance of 293 cell cycle phase on adenovirus vector production
-
Zhang CH, Ferreira TB, Cruz PE, Alves PM, Haury M, Carrondo MJT. The importance of 293 cell cycle phase on adenovirus vector production. Enzyme Microbial Technol. 2006; 39: 1328-1332.
-
(2006)
Enzyme Microbial Technol.
, vol.39
, pp. 1328-1332
-
-
Zhang, C.H.1
Ferreira, T.B.2
Cruz, P.E.3
Alves, P.M.4
Haury, M.5
Carrondo, M.J.T.6
|