Effect of NEFA and glucose levels on CPT-I mRNA expression and translation in cultured bovine hepatocytes

Journal of Veterinary Medical Science

Volumn 73, Issue 1, 2011, Pages 97-101

  Xu, Chuang ^a   Wang, Zhe ^b   Zhang, Ri he ^b   Zhang, Hong you ^a   Fu, Shi xin ^a   Xia, Cheng ^a  

^a HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

CPT I; Fatty acid transport; Glucose; Hepatocytes; NEFA

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; GLUCOSE; MESSENGER RNA;

ANIMAL; ARTICLE; CATTLE; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LIVER CELL; METABOLISM; PROTEIN SYNTHESIS;

ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; CATTLE; CELLS, CULTURED; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; GLUCOSE; HEPATOCYTES; PROTEIN BIOSYNTHESIS; RNA, MESSENGER;

BOVINAE;

EID: 79551699570     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.10-0164     Document Type: Article

References (19)

1. Aiello, R. J., Kenna, T. M. and Herbein, J. H. 1984. Hepatic gluconeogenic and ketogenic interrelationships in the lactating cow. J. Anim. Sci. 67: 1707-1715.
2. Barbara, L.G. 1997. Effects of the monensin controlled-release capsule on ruminal parameters and the occurrence of subclinical ketosis in transition dairy cows. A thesis Presented to The Facuity of Graduate Studies of The University of Guelph.
3. David, J., Waxman, J.J., Sharda, N. and Hugo, J. 1990. Phenobarbital induction of cytochromes P-450. Biochem. J. 271: 113-119.
4. Donkin, S.S. and Armentano, L.E. 1993. Preparation of extended in vitro cultures of bovine hepatocytes that are hormonally responsive. J. Anim. Sci. 71: 2218-2227.
5. Dann, H.M. and Drackley, J.K. 2005. Carnitine palmitoyltransferase I in liver of periparturient dairy cows: effects of prepartum intake, postpartum induction of ketosis, and periparturient disorders. J. Anim. Sci. 88: 3851-3859.
6. Hoppel, C.L. 1982. Carnitine and carnitine palmitoyltransferase in fatty acid oxidation and ketosis. Fed. Proc. 41: 2853-2857.
7. Kramer, K., Markwitan, A. and Pallauf, J. 1993. Studies on the metabolism of metallothionein and alkaline phosphatase of adult rat primary hepatocyte cultures: role off etal calfserum and agonists of the phosphoinositide cascade. Ernahrungs 32: 176-186.
8. Lucia, F., Fabrizio, A., Dario, D.M., Elisabetta, D. and Paolo, A. 2007. SYBR Green Real-Time PCR Method To Detect Clostridiumubotulinum TypeA. Appl. Environ. Microb. 73: 2891-2896.
9. Mills, S.E., Beitz, D.C. and Young, J.W. 1986. Evidence for Impaired Metabolism in Liver During Induced Lactation Ketosis of Dairy Cows. J. Dairy Sci. 69: 362-370.
10. Mizutani, H., Sako, T., Takemura, N., Koyama, H., Yamaguchi, M. and Motoyoshi, S. 1997. Hepatic carnitine palmitoyltransferase activity in cattle. J. Vet. Med. Sci. 59: 1067-1069.
11. Mizutani, H., Sako, T., Toyoda, Y., Kawabata, T., Urumuhang, N., Koyama, H. and Motoyoshi, S. 1999. Preliminary studies on hepatic carnitine palmitoyltransferase in dairy cattle with or without fatty liver. Vet. Res. Commun. 23: 475-480.
12. Melendez, P., Goff, J.P., Risco, C.A., Archbald, L.F., Littell, R. and Donovan, G.A. 2006. Incidence of subclinical ketosis in cows supplemented with a monensin controlled-release capsule in Holstein cattle, Florida, USA. Prev. Vet. Med. 73: 33-42.
13. Price, N.T., Jckson, V.N., Leij, F.R., Cameron, J.M., Travers, M.T., Bartelds, B., Huijkman, N.C. and Zammit, V.A. 2003. Cloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the Nterminus of the muscle isoform influence the kinetic properties of the enzyme. Biochem. J. 15: 871-879.
14. Strzalka, B., Dorecka, M., Stanik, A., Kowalczyk, M., Kapral, M., Romaniuk, W., Mazurek, U. and Swiatkowska, L. 2008. Quantitative Analysis of Transforming Growth Factor Isoforms mRNA in the Human Corneal Epithelium. Folia Biologica (Praha) 54: 46-52.
15. Xu, C. and Zhe, W. 2006. Effect of propionate, pyruvate and beta -hydroxybutyric acid on pyruvate carboxylase mRNA expression of in vitro culture bovine hepatocytes. Anim. Sci. J. 77: 440-446.
16. Xu, C., Wang, Z., Liu, G.W., Li, X.B., Xie, G.H., Xia, C. and Zhang, H.Y. 2008. Metabolic characteristic of the liver of dairy cows during ketosis based on comparative proteomics. Asian- Aust. J. Anim. Sci 21: 1003-1008.
17. Yamagishi, S.I., Edelstein, D., Du, X.L., Kaneda, Y., Guzmán, M. and Brownlee, M. 2001. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein- 1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J. Biol. Chem. 276: 25096-25100.
18. Zhu, L.H., Strang, B.D. and Armentano, L.E. 2000. Effects of triglyceride accumulation on induction of urea synthesis by glucagons and dexamethasone in monolayer cultures of bovine hepatocytes. J. Anim. Sci. 78: 1659-1666.
19. Zavana, B., Bruna, P., Vindignib, V., Amadoric, A., Habelerc, W., Pontissod, P., Montemurroe, D., Abatangeloa, G. and Cortivo, R. 2005. Extracellular matrix-enriched polymeric scaffolds as a substrate for hepatocyte cultures: in vitro and in vivo studies. Biomaterials 26: 7038-7045.