The GDNF target Vsnl1 marks the ureteric tip

Journal of the American Society of Nephrology

Volumn 22, Issue 2, 2011, Pages 274-284

  Ola, Roxana ^a   Jakobson, Madis ^a   Kvist, Jouni ^a,d   Perälä, Nina ^a   Kuure, Satu ^a,d   Braunewell, Karl Heinz ^b   Bridgewater, Darren ^c   Rosenblum, Norman D ^c   Chilov, Dmitri ^d   Immonen, Tiina ^a   Sainio, Kirsi ^a   Sariola, Hannu ^a,e  

^a UNIVERSITY OF HELSINKI   (Finland)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF HELSINKI   (Finland)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BIOLOGICAL MARKER; FOLLISTATIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; KERATINOCYTE GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEURONAL CALCIUM SENSOR; PROTEIN RET; TRANSCRIPTION FACTOR EMX2; UNCLASSIFIED DRUG; VISININ LIKE 1; WNT11 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STRUCTURES; GENE CONTROL; IN VIVO STUDY; KIDNEY COLLECTING TUBULE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; URETER; WESTERN BLOTTING;

EID: 79551668656     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2010030316     Document Type: Article

References (65)

1. Dressler GR: The cellular basis of kidney development. Annu Rev Cell Dev Biol 22: 509-529, 2006
2. Costantini F, Shakya R: GDNF/Ret signaling and the development of the kidney. Bioessays 28: 117-127, 2006
3. Suvanto P, Hiltunen JO, Arumae U, Moshnyakov M, Sariola H, Sainio K, Saarma M: Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization. Eur J Neurosci 8: 816-822, 1996
4. Jing S, Wen D, Yu Y, Holst PL, Luo Y, Fang M, Tamir R, Antonio L, Hu Z, Cupples R, Louis JC, Hu S, Altrock BW, Fox GM: GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85: 1113-1124, 1996
5. Sanicola M, Hession C, Worley D, Carmillo P, Ehrenfels C, Walus L, Robinson S, Jaworski G, Wei H, Tizard R, Whitty A, Pepinsky RB, Cate RL: Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. Proc Natl Acad Sci U.S.A. 94: 6238-6243, 1997
6. Treanor JJ, Goodman L, de Sauvage F, Stone DM, Poulsen KT, Beck CD, Gray C, Armanini MP, Pollock RA, Hefti F, Phillips HS, Goddard A, Moore MW, Buj-Bello A, Davies AM, Asai N, Takahashi M, Vandlen R, Henderson CE, Rosenthal A: Characterization of a multicomponent receptor for GDNF. Nature 382: 80-83, 1996
7. Cacalano G, Farinas I, Wang LC, Hagler K, Forgie A, Moore M, Armanini M, Phillips H, Ryan AM, Reichardt LF, Hynes M, Davies A, Rosenthal A: GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron 21: 53-62, 1998
8. Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H: Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382: 73-76, 1996 (Pubitemid 26243360)
9. Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V: Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367: 380-383, 1994
10. Sainio K, Suvanto P, Davies J, Wartiovaara J, Wartiovaara K, Saarma M, Arumae U, Meng X, Lindahl M, Pachnis V, Sariola H: Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124: 4077-4087, 1997
11. Shakya RE, Jho H, Kotka P, Wu Z, Kholodilov N, Burke R, D'Agati V, Costantini F: The role of GDNF in patterning the excretory system. Dev Biol 283: 70-84, 2005
12. Lu, BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, D'Agati V, Costantini F: Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nat Genet 41: 1295-1302, 2009
13. Pepicelli CV, Kispert A, Rowitch DH, McMahon AP: GDNF induces branching and increased cell proliferation in the ureter of the mouse. Dev Biol 192: 193-198, 1997
14. Shakya R, Watanabe T, Costantini F: The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis. Dev Cell 8: 65-74, 2005
15. Moore MW, Klein RD, Farinas I, Sauer H, Armanini M, Phillips H, Reichardt LF, Ryan AM, Carver-Moore K, Rosenthal A: Renal and neuronal abnormalities in mice lacking GDNF. Nature 382: 76-79, 1996
16. Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK: Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct. J Am Soc Nephrol 18: 3147-3155, 2007
17. Michos O, Cebrian C, Hyink D, Grieshammer U, Williams L, D'Agati V, Licht JD, Martin GR, Costantini F: Kidney development in the absence of Gdnf and Spry1 requires Fgf10. PLoS Genet 6: e1000809
18. Ohuchi H, Hori Y, Yamasaki M, Harada H, Sekine K, Kato S, Itoh N: FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development. Biochem Biophys Res Commun 277: 643-649, 2000
19. Qiao J, Uzzo R, Obara-Ishihara T, Degenstein L, Fuchs E, Herzlinger D: FGF-7 modulates ureteric bud growth and nephron number in the developing kidney. Development 126: 547-554, 1999 (Pubitemid 29082041)
20. Zhao H, Kegg H, Grady S, Truong HT, Robinson ML, Baum M, Bates CM: Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol 276: 403-415, 2004 (Pubitemid 39592403)
21. Cheon SS, Cheah AY, Turley S, Nadesan P, Poon R, Clevers H, Alman BA: beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. Proc Natl Acad Sci U.S.A. 99: 6973-6978, 2002
22. Maretto S, Cordenonsi M, Dupont S, Braghetta P, Broccoli V, Hassan AB, Volpin D, Bressan GM, Piccolo S: Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U.S.A. 100: 3299-3304, 2003
23. Iglesias DM, Hueber PA, Chu L, Campbell R, Patenaude AM, Dziarmaga AJ, Quinlan J, Mohamed O, Dufort D, Goodyer PR: Canonical WNT signaling during kidney development. Am J Physiol Renal Physiol 293: F494-F500, 2007
24. Merkel, CE, Karner CM, Carroll TJ: Molecular regulation of kidney development: Is the answer blowing in the Wnt? Pediatr Nephrol 22: 1825-1838, 2007
25. Bridgewater D, Cox B, Cain J, Lau A, Athaide V, Gill PS, Kuure S, Sainio K, Rosenblum ND: Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol 317: 83-94, 2008
26. Marose, TD, Merkel CE, McMahon AP, Carroll TJ: Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol 314: 112-126, 2008
27. Schwab K, Patterson LT, Aronow BJ, Luckas R, Liang HC, Potter SS: A catalogue of gene expression in the developing kidney. Kidney Int 64: 1588-1604, 2003 (Pubitemid 37323687)
28. Gierke P, Zhao C, Brackmann M, Linke B, Heinemann U, Braunewell KH: Expression analysis of members of the neuronal calcium sensor protein family: Combining bioinformatics and Western blot analysis. Biochem Biophys Res Commun 323: 38-43, 2004 (Pubitemid 39200645)
29. Spilker C, Dresbach T, Braunewell KH: Reversible translocation and activity-dependent localization of the calcium-myristoyl switch protein VILIP-1 to different membrane compartments in living hippocampal neurons. J Neurosci 22: 7331-7339, 2002
30. Zozulya S, Stryer L: Calcium-myristoyl protein switch. Proc Natl Acad Sci U.S.A. 89: 11569-11573, 1992
31. 2+ sensor protein VILIP-1 affects cGMP signalling of guanylyl cyclase B by regulating clathrin-dependent receptor recycling in hippocampal neurons. J Cell Sci 118: 2495-2505, 2005
32. 2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion. J Biol Chem 281: 21942-21953, 2006
33. Basson, MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD: Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell 8: 229-239, 2005
34. de Graaff E, Srinivas S, Kilkenny C, D'Agati V, Mankoo BS, Costantini F, Pachnis V: Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes Dev 15: 2433-2444, 2001
35. Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K, Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little MH, Bertram JF: Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns 6: 807-825, 2006 (Pubitemid 44309434)
36. Schmidt-Ott, KM, Yang J, Chen X, Wang H, Paragas N, Mori K, Li JY, Lu B, Costantini F, Schiffer M, Bottinger E, Barasch J: Novel regulators of kidney development from the tips of the ureteric bud. J Am Soc Nephrol 16: 1993-2002, 2005
37. Schwab K, Hartman HA, Liang HC, Aronow BJ, Patterson LT, Potter SS: Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development. Dev Biol 293: 540-554, 2006
38. Sonnenberg E, A. Godecke, B. Walter, F. Bladt, C. Birchmeier: Transient and locally restricted expression of the ros1 protooncogene during mouse development. EMBO J 10: 3693-3702, 1991
39. Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP: Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 130: 3175-3185, 2003
40. Corson, LB, Yamanaka Y, Lai KM, Rossant J: Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130: 4527-4537, 2003 (Pubitemid 37279407)
41. Lunn JS, Fishwick KJ, Halley PA, Storey KG: A spatial and temporal map of FGF/Erk1/2 activity and response repertoires in the early chick embryo. Dev Biol 302: 536-552, 2007
42. Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F: Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev Cell 17: 199-209, 2009
43. Steer DL, Shah MM, Bush KT, Stuart RO, Sampogna RV, Meyer TN, Schwesinger C, Bai X, Esko JD, Nigam SK: Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney. Dev Biol 272: 310-327, 2004 (Pubitemid 38988259)
44. Schneider I, Houston DW, Rebagliati MR, Slusarski DC: Calcium fluxes in dorsal forerunner cells antagonize beta-catenin and alter left-right patterning. Development 135: 75-84, 2008
45. Maye P, Zheng J, Li L, Wu D: Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway. J Biol Chem 279: 24659-24665, 2004
46. Braunewell KH, Spilker C, Behnisch T, Gundelfinger ED: The neuronal calcium-sensor protein VILIP modulates cyclic AMP accumulation in stably transfected C6 glioma cells: Amino-terminal myristoylation determines functional activity. J Neurochem 68: 2129-2139, 1997
47. Nozaki C, Asai N, Murakami H, Iwashita T, Iwata Y, Horibe K, Klein RD, Rosenthal A, Takahashi M: Calcium-dependent Ret activation by GDNF and neurturin. Oncogene 16: 293-299, 1998 (Pubitemid 28052283)
48. van Weering DH, Moen TC, Braakman I, Baas PD, Bos JL: Expression of the receptor tyrosine kinase Ret on the plasma membrane is dependent on calcium. J Biol Chem 273: 12077-12081, 1998
49. Huelsken J, Behrens J: The Wnt signalling pathway. J Cell Sci 115: 3977-3978, 2002
50. Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, Arthur WT, Moon RT: New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening. Sci Signal 1: ra12, 2008
51. Gentleman, RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J: Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol 5: R80, 2004
52. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP: Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264, 2003
53. Dai M, Wang P, Boyd AD, Kostov G, Athey B, Jones EG, Bunney WE, Myers RM, Speed TP, Akil H, Watson SJ, Meng F: Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 33: e175, 2005
54. Smyth GK: Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: Article3, 2004
55. Charif D, Thioulouse J, Lobry JR, Perriere G: Online synonymous codon usage analyses with the ade4 and seqinR packages. Bioinformatics 21: 545-547, 2005
56. Schuchardt A, D'Agati V, Pachnis V, Costantini F: Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development. Development 122: 1919-1929, 1996
57. Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM: Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 18: 5931-5942, 1999
58. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R: Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264, 2001
59. Godin RE, Takaesu NT, Robertson EJ, Dudley AT: Regulation of BMP7 expression during kidney development. Development 125: 3473-3482, 1998
60. Sariola H, Aufderheide E, Bernhard H, Henke-Fahle S, Dippold W, Ekblom P: Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions. Cell 54: 235-245, 1988
61. Sariola H, Holm K, Henke-Fahle S: Early innervation of the metanephric kidney. Development 104: 589-599, 1988
62. Kuure S, Sainio K, Vuolteenaho R, Ilves M, Wartiovaara K, Immonen T, Kvist J, Vainio S, Sariola H: Crosstalk between Jagged1 and GDNF/Ret/GFRalpha1 signalling regulates ureteric budding and branching. Mech Dev 122: 765-780, 2005
63. Pachnis V, Mankoo B, Costantini F: Expression of the c-ret protooncogene during mouse embryogenesis. Development 119: 1005-1017, 1993
64. Jadeja S, Smyth I, Pitera JE, Taylor MS, van Haelst M, Bentley E, McGregor L, Hopkins J, Chalepakis G, Philip N, Perez Aytes A, Watt FM, Darling SM, Jackson I, Woolf AS, Scambler PJ: Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet 37: 520-525, 2005
65. Lindahl M, Poteryaev D, Yu L, Arumae U, Timmusk T, Bongarzone I, Aiello A, Pierotti MA, Airaksinen MS, Saarma M: Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells. J Biol Chem 276: 9344-9351, 2001