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Volumn 8, Issue 2, 2011, Pages 208-212

Aerosol delivery of antimicrobial agents during mechanical ventilation: Current practice and perspectives

Author keywords

Antibiotics; Delivery system; Inhalation; Nebulization; Ventilation

Indexed keywords

ANTIINFECTIVE AGENT; AZTREONAM LYSINE; COLISTIN; PENTAMIDINE; TOBRAMYCIN;

EID: 79551627449     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720111794479880     Document Type: Article
Times cited : (9)

References (42)
  • 1
    • 33847122008 scopus 로고    scopus 로고
    • Local administration of polymyxins into the respiratory tract for the prevention and treatment of pulmonary infections in patients without cystic fibrosis
    • Falagas, M.E.; Kasiakou, S.K. Local administration of polymyxins into the respiratory tract for the prevention and treatment of pulmo-nary infections in patients without cystic fibrosis. Infection, 2007, 35(1), 3-10.
    • (2007) Infection , vol.35 , Issue.1 , pp. 3-10
    • Falagas, M.E.1    Kasiakou, S.K.2
  • 2
    • 0034828531 scopus 로고    scopus 로고
    • Formulation of aerosolized therapeutics
    • Kuhn, R.J. Formulation of aerosolized therapeutics. Chest, 2001, 120(3 Suppl), 94S-98S.
    • (2001) Chest , vol.120 , Issue.3 SUPPL.
    • Kuhn, R.J.1
  • 3
    • 34247551021 scopus 로고    scopus 로고
    • Administration of antibiotics via the respiratory tract for the prevention of ICU-acquired pneumonia: A meta-analysis of comparative trials
    • Falagas, M.E.; Siempos, I.I.; Bliziotis, I.A.; Michalopoulos, A. Administration of antibiotics via the respiratory tract for the prevention of ICU-acquired pneumonia: a meta-analysis of comparative trials. Crit. Care, 2006, 10(4), R123.
    • (2006) Crit. Care , vol.10 , Issue.4
    • Falagas, M.E.1    Siempos, I.I.2    Bliziotis, I.A.3    Michalopoulos, A.4
  • 4
    • 79551638816 scopus 로고    scopus 로고
    • FDA
    • FDA. Colistimethate. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforP%atientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm084285.h%tm.
    • Colistimethate
  • 6
    • 79551643931 scopus 로고    scopus 로고
    • Novartis
    • Novartis. TOBI Package Insert. http://www.pharma.us.novartis.com/product/pi/pdf/tobi.pdf.
    • TOBI Package Insert
  • 7
    • 33745910567 scopus 로고    scopus 로고
    • The use of intravenous and aerosolized polymyxins for the treatment of infections in critically ill patients: A review of the recent literature
    • Falagas, M.E.; Kasiakou, S.K.; Tsiodras, S.; Michalopoulos, A. The use of intravenous and aerosolized polymyxins for the treatment of infections in critically ill patients: a review of the recent literature. Clin. Med. Res., 2006, 4(2), 138-146.
    • (2006) Clin. Med. Res , vol.4 , Issue.2 , pp. 138-146
    • Falagas, M.E.1    Kasiakou, S.K.2    Tsiodras, S.3    Michalopoulos, A.4
  • 8
    • 33644661602 scopus 로고    scopus 로고
    • Comparing clinical features of the nebulizer, metered-dose inhaler, and dry powder inhaler
    • Geller, D.E. Comparing clinical features of the nebulizer, metered-dose inhaler, and dry powder inhaler. Respir. Care, 2005, 50(10), 1313-1321.
    • (2005) Respir. Care , vol.50 , Issue.10 , pp. 1313-1321
    • Geller, D.E.1
  • 9
    • 0033932274 scopus 로고    scopus 로고
    • Aerosolized antibiotics: Current and future
    • Smaldone, G.C.; Palmer, L.B. Aerosolized antibiotics: current and future. Respir. Care, 2000, 45(6), 667-675.
    • (2000) Respir. Care , vol.45 , Issue.6 , pp. 667-675
    • Smaldone, G.C.1    Palmer, L.B.2
  • 10
    • 0035164687 scopus 로고    scopus 로고
    • Inhalation therapy during mechanical ventilation
    • Duarte, A.G.; Fink, J.B.; Dhand, R. Inhalation therapy during mechanical ventilation. Respir. Care Clin. N. Am., 2001, 7(2), 233-260.
    • (2001) Respir. Care Clin. N. Am , vol.7 , Issue.2 , pp. 233-260
    • Duarte, A.G.1    Fink, J.B.2    Dhand, R.3
  • 11
    • 42649097553 scopus 로고    scopus 로고
    • Aerosol delivery during mechanical ventilation: From basic techniques to new devices
    • Dhand, R. Aerosol delivery during mechanical ventilation: from basic techniques to new devices. J. Aerosol. Med. Pulm. Drug Deliv., 2008, 21(1), 45-60.
    • (2008) J. Aerosol. Med. Pulm. Drug Deliv , vol.21 , Issue.1 , pp. 45-60
    • Dhand, R.1
  • 12
    • 22144446795 scopus 로고    scopus 로고
    • In vitro evaluation of bronchodilator drug delivery by jet nebulization during pediatric mechanical ventilation
    • Di Paolo, E.R.; Pannatier, A.; Cotting, J. In vitro evaluation of bronchodilator drug delivery by jet nebulization during pediatric mechanical ventilation. Pediat. Crit. Care Med., 2005, 6(4), 462-469.
    • (2005) Pediat. Crit. Care Med , vol.6 , Issue.4 , pp. 462-469
    • Di Paolo, E.R.1    Pannatier, A.2    Cotting, J.3
  • 13
    • 21244459475 scopus 로고    scopus 로고
    • In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation
    • Vecellio, L.; Guerin, C.; Grimbert, D.; De Monte, M.; Diot, P. In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation. Intensive Care Med., 2005, 31(6), 871-876.
    • (2005) Intensive Care Med , vol.31 , Issue.6 , pp. 871-876
    • Vecellio, L.1    Guerin, C.2    Grimbert, D.3    de Monte, M.4    Diot, P.5
  • 14
  • 15
    • 0035020498 scopus 로고    scopus 로고
    • In vitro characteristics of tobramycin aerosol from ultrasonic and jet nebulizers
    • Asmus, M.J.; Milavetz, G.; Tice, A.L.; Teresi M.E. In vitro characteristics of tobramycin aerosol from ultrasonic and jet nebulizers. Pharmacother., 2001, 21 (5), 534-539.
    • (2001) Pharmacother , vol.21 , Issue.5 , pp. 534-539
    • Asmus, M.J.1    Milavetz, G.2    Tice, A.L.3    Teresi, M.E.4
  • 16
    • 0023588217 scopus 로고
    • In vitro comparison of DeVilbiss jet and ultrasonic nebulizers
    • Newman, S.P.; Pellow, P.G.; Clarkem S.W. In vitro comparison of DeVilbiss jet and ultrasonic nebulizers. Chest, 1987, 92 (6), 991-994.
    • (1987) Chest , vol.92 , Issue.6 , pp. 991-994
    • Newman, S.P.1    Pellow, P.G.2    Clarkem, S.W.3
  • 17
    • 0030999183 scopus 로고    scopus 로고
    • A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems. Aerosolized Tobramycin Study Group
    • Eisenberg, J.; Pepe, M.; Williams-Warren, J.; Vasiliev, M.; Mont-gomery, A.B.; Smith, A.L.; Ramsey, B.W. A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems. Aerosolized Tobramycin Study Group. Chest, 1997, 111(4), 955-962.
    • (1997) Chest , vol.111 , Issue.4 , pp. 955-962
    • Eisenberg, J.1    Pepe, M.2    Williams-Warren, J.3    Vasiliev, M.4    Mont-Gomery, A.B.5    Smith, A.L.6    Ramsey, B.W.7
  • 18
    • 0029763316 scopus 로고    scopus 로고
    • Medication nebulizer performance: Effects of diluent volume, nebulizer flow, and nebulizer brand
    • Hess, D.; Fisher, D.; Williams, P.; Pooler, S.; Kacmarek, R.M. Medication nebulizer performance: effects of diluent volume, nebulizer flow, and nebulizer brand. Chest, 1996, 110 (2), 498-505.
    • (1996) Chest , vol.110 , Issue.2 , pp. 498-505
    • Hess, D.1    Fisher, D.2    Williams, P.3    Pooler, S.4    Kacmarek, R.M.5
  • 19
    • 0031975321 scopus 로고    scopus 로고
    • Aerosolized antibiotics in mechanically ventilated patients: Delivery and response
    • Palmer, L.B.; Smaldone, G.C.; Simon, S.R.; O'Riordan, T.G.; Cuccia A. Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Crit. Care Med., 1998, 26(1), 31-39.
    • (1998) Crit. Care Med , vol.26 , Issue.1 , pp. 31-39
    • Palmer, L.B.1    Smaldone, G.C.2    Simon, S.R.3    O'Riordan, T.G.4    Cuccia, A.5
  • 20
    • 66849121732 scopus 로고    scopus 로고
    • New aerosol delivery devices for cystic fibrosis
    • Kesser, K.C.; Geller, D.E. New aerosol delivery devices for cystic fibrosis. Respir. Care, 2009, 54(6), 754-768.
    • (2009) Respir. Care , vol.54 , Issue.6 , pp. 754-768
    • Kesser, K.C.1    Geller, D.E.2
  • 21
    • 4644343918 scopus 로고    scopus 로고
    • Basic techniques for aerosol delivery during mechanical ventilation
    • Dhand, R. Basic techniques for aerosol delivery during mechanical ventilation. Respir. Care, 2004, 49(6), 611-622.
    • (2004) Respir. Care , vol.49 , Issue.6 , pp. 611-622
    • Dhand, R.1
  • 23
    • 0034546826 scopus 로고    scopus 로고
    • Technical report: Precautions regarding the use of aerosolized antibiotics. Committee on infectious diseases and committee on drugs
    • Prober, C.G.; Walson, P.D.; Jones, J. Technical report: precautions regarding the use of aerosolized antibiotics. Committee on infectious diseases and committee on drugs. Pediatics, 2000, 106(6), E89.
    • (2000) Pediatics , vol.106 , Issue.6
    • Prober, C.G.1    Walson, P.D.2    Jones, J.3
  • 24
    • 66849138758 scopus 로고    scopus 로고
    • Infection control in cystic fibrosis: Cohorting, cross contamination, and the respiratory therapist
    • O'Malley, C.A. Infection control in cystic fibrosis: cohorting, cross contamination, and the respiratory therapist. Respir. Care, 2009, 54(5), 641-655.
    • (2009) Respir. Care , vol.54 , Issue.5 , pp. 641-655
    • O'Malley, C.A.1
  • 26
    • 77149157841 scopus 로고    scopus 로고
    • Generation of liposome aerosols with the Aeroneb Pro and the AeroProbe nebulizers
    • Gaspar, M.M.; Gobbo, O., Ehrhardt, C. Generation of liposome aerosols with the Aeroneb Pro and the AeroProbe nebulizers. J. Liposome Res., 2010, 20(1), 55-61.
    • (2010) J. Liposome Res , vol.20 , Issue.1 , pp. 55-61
    • Gaspar, M.M.1    Gobbo, O.2    Ehrhardt, C.3
  • 27
    • 38749095520 scopus 로고    scopus 로고
    • Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: A prospective study
    • Michalopoulos, A.; Fotakis, D.; Virtzili, S.; Vletsas, C.; Raftopou-lou, S.; Mastora, Z.; Falagas, M.E. Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: a prospective study. Respir. Med., 2008, 102(3), 407-412.
    • (2008) Respir. Med , vol.102 , Issue.3 , pp. 407-412
    • Michalopoulos, A.1    Fotakis, D.2    Virtzili, S.3    Vletsas, C.4    Raftopou-Lou, S.5    Mastora, Z.6    Falagas, M.E.7
  • 28
    • 0034219390 scopus 로고    scopus 로고
    • Inhaled antimicrobial therapy: From cystic fibrosis to the flu
    • O'Riordan, T.G. Inhaled antimicrobial therapy: from cystic fibrosis to the flu. Respir. Care, 2000, 45(7), 836-845.
    • (2000) Respir. Care , vol.45 , Issue.7 , pp. 836-845
    • O'Riordan, T.G.1
  • 29
    • 38349081527 scopus 로고    scopus 로고
    • Guiding aerosol deposition in the lung
    • Coates, A.L. Guiding aerosol deposition in the lung. N. Engl. J. Med., 2008, 358, 304-305.
    • (2008) N. Engl. J. Med , vol.358 , pp. 304-305
    • Coates, A.L.1
  • 30
    • 0033983320 scopus 로고    scopus 로고
    • Aerosolized antimicrobial therapy in acutely ill patients
    • Wood, G.C.; Boucher, B.A. Aerosolized antimicrobial therapy in acutely ill patients. Pharmacother., 2000, 20(2), 166-181.
    • (2000) Pharmacother , vol.20 , Issue.2 , pp. 166-181
    • Wood, G.C.1    Boucher, B.A.2
  • 31
    • 0020613038 scopus 로고
    • Factors influencing the size distribution of aerosols from jet nebulizers
    • Clay, M.M.; Pavia, D.; Newman, S.P.; Clark, S.W. Factors influencing the size distribution of aerosols from jet nebulizers. Thorax 1983, 38 (10), 755-759.
    • (1983) Thorax , vol.38 , Issue.10 , pp. 755-759
    • Clay, M.M.1    Pavia, D.2    Newman, S.P.3    Clark, S.W.4
  • 32
    • 0033786617 scopus 로고    scopus 로고
    • Targeting aerosol deposition in patients with cystic fibrosis: Effects of alteration in particle size and inspiratory flow rate
    • Laube, B.L.; Jashnani, R.; Dalby, R.N.; Zeitlin, P.L. Targeting aerosol deposition in patients with cystic fibrosis: effects of alteration in particle size and inspiratory flow rate. Chest, 2000, 118 (4), 1069-1076.
    • (2000) Chest , vol.118 , Issue.4 , pp. 1069-1076
    • Laube, B.L.1    Jashnani, R.2    Dalby, R.N.3    Zeitlin, P.L.4
  • 33
    • 0025980659 scopus 로고
    • Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection
    • Smaldone, G.C.; Fuhrer, J.; Steigbigel, R.T.; McPeck, M. Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection. Am. Rev. Respir. Dis., 1991, 143 (4 Pt 1), 727-737.
    • (1991) Am. Rev. Respir. Dis , vol.143 , Issue.4 Pt 1 , pp. 727-737
    • Smaldone, G.C.1    Fuhrer, J.2    Steigbigel, R.T.3    McPeck, M.4
  • 34
    • 0025840212 scopus 로고
    • Aerosol generators and delivery systems
    • Newman, S.P. Aerosol generators and delivery systems. Respir. Care, 1991, 36 (9), 939-951.
    • (1991) Respir. Care , vol.36 , Issue.9 , pp. 939-951
    • Newman, S.P.1
  • 35
    • 23644458446 scopus 로고    scopus 로고
    • The customised electronic nebuliser: A new category of liquid aerosol drug delivery systems
    • Knoch, M.; Keller, M. The customised electronic nebuliser: a new category of liquid aerosol drug delivery systems. Expert Opin. Drug Deliv., 2005, 2 (2), 377-390.
    • (2005) Expert Opin. Drug Deliv , vol.2 , Issue.2 , pp. 377-390
    • Knoch, M.1    Keller, M.2
  • 36
    • 0036198938 scopus 로고    scopus 로고
    • The rationale for aerosolized antibiotics
    • Flume, P.; Klepser, M.E. The rationale for aerosolized antibiotics. Pharmacother., 2002, 22(3 pt 2), S71-79.
    • (2002) Pharmacother , vol.22 , Issue.3 Pt 2
    • Flume, P.1    Klepser, M.E.2
  • 37
    • 34247186991 scopus 로고    scopus 로고
    • Aerosolised antibacterials for the prevention and treatment of hospital-acquired pneumonia
    • Wood, G.C.; Swanson, J.M. Aerosolised antibacterials for the prevention and treatment of hospital-acquired pneumonia. Drugs, 2007, 67(6), 903-914.
    • (2007) Drugs , vol.67 , Issue.6 , pp. 903-914
    • Wood, G.C.1    Swanson, J.M.2
  • 38
    • 0026465629 scopus 로고
    • Gamma scintigraphy in the evaluation of pharmaceutical dosage forms (review)
    • Davis, S.S., Hardy, J.G., Newman, S.P., Wilding, I.R. Gamma scintigraphy in the evaluation of pharmaceutical dosage forms (review). Eur. J. Nucl. Med., 1992, 19(11), 971-986.
    • (1992) Eur. J. Nucl. Med , vol.19 , Issue.11 , pp. 971-986
    • Davis, S.S.1    Hardy, J.G.2    Newman, S.P.3    Wilding, I.R.4
  • 39
    • 34247193128 scopus 로고    scopus 로고
    • Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
    • Geller, D.E.; Konstan, M.W.; Smith, J.; Noonberg, S.B.; Conrad, C. Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediat. Pulmonol., 2007, 42 (4), 307-313.
    • (2007) Pediat. Pulmonol , vol.42 , Issue.4 , pp. 307-313
    • Geller, D.E.1    Konstan, M.W.2    Smith, J.3    Noonberg, S.B.4    Conrad, C.5
  • 40
    • 23744466563 scopus 로고    scopus 로고
    • Penetration of gentamicin into the alveolar lining fluid of critically ill patients with ventilator-associated pneumonia
    • Panidis, D.; Markantonis, S.L.; Boutzouka, E.; Karatzas, S.; Baltopoulos, G. Penetration of gentamicin into the alveolar lining fluid of critically ill patients with ventilator-associated pneumonia. Chest, 2005, 128(2), 545-552.
    • (2005) Chest , vol.128 , Issue.2 , pp. 545-552
    • Panidis, D.1    Markantonis, S.L.2    Boutzouka, E.3    Karatzas, S.4    Baltopoulos, G.5
  • 41
    • 0018776450 scopus 로고
    • Endotracheally administered antibiotics for gram-negative bronchopneumonia
    • Klastersky, J.; Carpentier-Meunier, F.; Kahan-Coppens, L.; Thys, J.P. Endotracheally administered antibiotics for gram-negative bronchopneumonia. Chest, 1979, 75(5), 586-591.
    • (1979) Chest , vol.75 , Issue.5 , pp. 586-591
    • Klastersky, J.1    Carpentier-Meunier, F.2    Kahan-Coppens, L.3    Thys, J.P.4
  • 42
    • 34249938781 scopus 로고    scopus 로고
    • Efficacy, safety, and local pharmacokinetics of highly concentrated nebulized tobramy-cin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa
    • Lenoir, G.; Antypkin, Y.G.; Miano, A.; Moretti, P.; Zanda, M.; Varoli, G.; Monici Preti, P.A.; Aryayev, N.L. Efficacy, safety, and local pharmacokinetics of highly concentrated nebulized tobramy-cin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa. Paediatr. Drugs, 2007, 9 (Suppl 1), 11-20.
    • (2007) Paediatr. Drugs , vol.9 , Issue.SUPPL. 1 , pp. 11-20
    • Lenoir, G.1    Antypkin, Y.G.2    Miano, A.3    Moretti, P.4    Zanda, M.5    Varoli, G.6    Monici, P.P.A.7    Aryayev, N.L.8


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