Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action

Environmental and Molecular Mutagenesis

Volumn 52, Issue 2, 2011, Pages 153-160

  Ridpath, John R ^a   Takeda, Shunichi ^b   Swenberg, James A ^a,c   Nakamura, Jun ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b Department of Radiation Genetics Graduate School of Medicine ^*  (Japan)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

DNA damage response; DT40; Genotoxicity assay

Indexed keywords

MUTAGENIC AGENT;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CHEMICAL INDUSTRY; CHICKEN; DNA DAMAGE; DT40 CELL LINE; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; HIGH THROUGHPUT SCREENING; MAMMAL CELL; MUTANT; NONHUMAN; YEAST;

ANIMALS; CELL LINE; CELL SURVIVAL; CHICKENS; DNA DAMAGE; DNA REPAIR; HIGH-THROUGHPUT SCREENING ASSAYS; INDICATORS AND REAGENTS; MUTAGENICITY TESTS; TETRAZOLIUM SALTS;

ANIMALIA; MAMMALIA;

EID: 79551603807     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20595     Document Type: Article

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