On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure

Food and Chemical Toxicology

Volumn 49, Issue 3, 2011, Pages 571-578

  Kassa, Roman M ^a   Kasensa, Nyamabo L ^c   Monterroso, Victor H ^a   Kayton, Robert J ^a   Klimek, John E ^a   David, Larry L ^a   Lunganza, Kalala R ^c   Kayembe, Kazadi T ^c   Bentivoglio, Marina ^d   Juliano, Sharon L ^e   Tshala Katumbay, Desire D ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF KINSHASA   (Congo)

^d UNIVERSITY OF VERONA   (Italy)

^e UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Biomarkers; Cassava; Cyanate; Konzo; Linamarin; Proteomics

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN 3; ALBUMIN; ALPHA2 SPECTRIN; ATP CITRATE LYASE ISOFORM 2; DIHYDROPYRIMIDINASE LIKE 2; DYNAMIN I; GELSOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN DELTA; HEAT SHOCK PROTEIN 8; LINAMARIN; MEMBRANE PROTEIN; N ETHYLMALEIMIDE SENSITIVE FACTOR; NEUROFILAMENT LIGHT POLYPEPTIDE; NEUROFILAMENT MEDIUM POLYPEPTIDE; NEUROFILAMENT PROTEIN; PEROXIREDOXIN 6; PROTEIN DISULFIDE ISOMERASE ASSOCIATED 3; PROTEIN SPNA2; PROTEOME; PYRUVATE DEHYDROGENASE E1 ALPHA FORM 1 SUBUNIT; RADIXIN; SODIUM CYANATE; SULFUR AMINO ACID; SYNTAXIN BINDING PROTEIN 1; TUBULIN T BETA 15; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CARBAMOYLATION; CASSAVA; CONTROLLED STUDY; CYANOGENESIS; DISEASE ASSOCIATION; ENDOSOME; FOOD INTAKE; FOOD POISONING; HIND LIMB TREMOR; INTOXICATION; KONZO; LIMB TREMOR; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOTOR NEURON DISEASE; MOTOR WEAKNESS; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS; WEAKNESS;

AMINO ACID SEQUENCE; AMINO ACIDS, SULFUR; ANIMALS; BIOLOGICAL MARKERS; CYANATES; DIET; MALE; MANIHOT; MOTOR NEURON DISEASE; NITRILES; PROTEOME; RATS; RATS, NUDE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THIOCYANATES; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

ANIMALIA; MANIHOT ESCULENTA; RATTUS;

EID: 79551600422     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.05.080     Document Type: Article

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