Estimation of the Partitioning Characteristics of Drugs: A Comparison of a Large and Diverse Drug Series Utilizing Chromatographic and Electrophoretic Methodology

Analytical Chemistry

Volumn 70, Issue 10, 1998, Pages 2092-2099

  Hanna, Melissa ^a   De Biasi, Vern ^b   Bond, Brian ^b   Salter, Colin ^b   Hutt, Andrew J ^a   Camilleri, Patrick ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BUFFER; DRUG; OCTANOL; PHOSPHATIDYLCHOLINE; WATER;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMISTRY; COMPARATIVE STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; MICELLE; STATISTICAL ANALYSIS;

1-OCTANOL; BILE ACIDS AND SALTS; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA INTERPRETATION, STATISTICAL; ELECTROPHORESIS, CAPILLARY; MICELLES; PHARMACEUTICAL PREPARATIONS; PHOSPHATIDYLCHOLINES; WATER;

EID: 0032523530     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac971122l     Document Type: Article

References (18)

1. Hansch, C.; Leo, A. In Substituent Constants For Correlation Analysis in Chemistry and Biology; Wiley: New York, 1979.
2. Leo, A.; Hansch, C.; Elkins, D. Chem. Rev. 1971, 71, 525.
3. Braumann, T. J. Chromatogr. 1986, 373, 191.
4. Kaliszan, R. Quantitative Structure Chromatographic Retention Relationships; Wiley: New York, 1987.
5. Lambert, W. J. J. Chromatogr. 1993, 656, 469.
6. Valko, K.; Bevan, C.; Reynolds, D. Anal. Chem. 1997, 69, 2022.
7. Yang, C. Y.; Cai, S. J.; Liu, H.; Pidgeon, C. Adv. Drug. Del. Rev. 1996, 23, 229.
8. Pidgeon, C.; Marcus, C.; Alvarez, F. In Applications of Enzyme Biotechnology, Kelly, J. W., Baldwin, T. O., Eds.; Plenum Press: New York, 1991; p 201-220.
9. Adlard, M.; Okafo, G.; Meenan, E.; Camilleri, P. J. Chem. Soc., Chem. Commun. 1995, 2241.
10. Ishihama, Y.; Oda, Y.; Uchikawa, K.; Asakawa, N. Anal. Chem. 1995, 67, 1588.
11. Herbert, B. J.; Dorsey, J. G. Anal. Chem. 1995, 67, 744.
12. Craig, P. N. In Cumulative Subject Index and Drug Compendium; Drayton, C. I., Ed.; Hansch, C., Sammes, P. G., Taylor, J. B., Eds., Comprehensive Medicinal Chemistry; Pergamon Press: Oxford, U.K., 1990; pp 237-991.
13. Cook, R. D. Tecknometrics 1977, 19, 15.
14. Cook. R. D. J. Am. Stat. Assoc. 1979, 74, 169.
15. Draper, N. R.; Smith, H. Applied Regression Analysis, 2nd ed.; Wiley: New York, 1981; pp 69-71.
16. Austin, R. P.; Davis, A. M.; Manners, C. N. C. J. Pharm. Sci. 1995, 84, 1180.
17. Barbato, F.; Rotonda, M.; Quaglia, F. J. Pharm. Sci. 1997, 86, 225.
18. Salminen, T.; Pulli, A.; Taskinen, J. J. Pharm. Biomed. Anal. 1997, 15, 469.