Different retention behavior of structurally diverse basic and neutral drugs in immobilized artificial membrane and reversed-phase high performance liquid chromatography: Comparison with octanol-water partitioning

Journal of Chromatography A

Volumn 1116, Issue 1-2, 2006, Pages 158-164

  Vrakas, Demetris ^a   Giaginis, Costas ^a   Tsantili Kakoulidou, Anna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

Electrostatic interactions; Immobilized artificial membrane chromatography; Octanol water partitioning; Principal component analysis; Reversed phase HPLC

Indexed keywords

DATA ACQUISITION; DRUG PRODUCTS; ELECTROSTATICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH EFFECTS; PRINCIPAL COMPONENT ANALYSIS;

IMMOBILIZED ARTIFICIAL MEMBRANE CHROMATOGRAPHY; OCTANOL-WATER PARTITIONING; REVERSED-PHASE HPLC;

BIOLOGICAL MEMBRANES;

ACICLOVIR; AMITRIPTYLINE; AMLODIPINE; ATENOLOL; BROMAZEPAM; CLOMIPRAMINE; CLOPAMIDE; DIAZEPAM; DILTIAZEM; DIMETINDENE; DIPYRIDAMOLE; DOXEPIN; HALOPERIDOL; IMIPRAMINE; LIDOCAINE; LORAZEPAM; MAPROTILINE; METFORMIN; MIDAZOLAM; MORPHOLINEPROPANESULFONIC ACID; NEOSTIGMINE; NIFEDIPINE; NORTRIPTYLINE; OCTANOL; PHOSPHATE BUFFERED SALINE; SULFONIC ACID DERIVATIVE; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; WATER;

ANALYTIC METHOD; ARTICLE; CORRELATIONAL STUDY; DRUG RETENTION; ELECTRICITY; HYDROPHOBICITY; IMMOBILIZED ARTIFICIAL MEMBRANE CHROMATOGRAPHY; INTERMETHOD COMPARISON; LIPOPHILICITY; PARTITION CHROMATOGRAPHY; PARTITION COEFFICIENT; PH; PRIORITY JOURNAL; REGRESSION ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MEMBRANES, ARTIFICIAL; OCTANOLS; PHARMACEUTICAL PREPARATIONS; WATER;

EID: 33646490096     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.03.058     Document Type: Article

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