Central interleukin-10 attenuated lipopolysaccharide-induced changes in core temperature and hypothalamic glutamate, hydroxyl radicals and prostaglandin-E2

European Journal of Pharmacology

Volumn 654, Issue 2, 2011, Pages 187-193

  Kao, Cheng Hsing ^a,b   Huang, Wu Tein ^c   Lin, Mao Tsun ^a,d   Wu, Wen Shiann ^a  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Fever; Glutamate; Hydroxyl radicals; Interleukin 10; Lipopolysaccharide; Prostaglandin E 2

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUTAMIC ACID; HYDROXYL RADICAL; INTERLEUKIN 10; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ANTIPYRETIC ACTIVITY; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORE TEMPERATURE; DRUG EFFECT; EXTRACELLULAR SPACE; FEVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RABBIT;

ANIMALS; BODY TEMPERATURE; CATECHOLS; DINOPROSTONE; FEVER; GLUTAMIC ACID; HYDROXYL RADICAL; HYPOTHALAMUS; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MALE; MICRODIALYSIS; RABBITS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79551589235     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.12.038     Document Type: Article

References (48)

1. Bachis, A., Colangelo, A.M., Vicini, S., Doe, P.P., De Bernardi M.A., Brooker, G., Mocchetti, I., 2001. Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. J. Neurosci. 21, 3104-3112.
2. D.J. Berg, R. Kuhn, K. Rajewsky, W. Muller, S. Menon, N. Davidson, G. Grunig, and D. Rennick Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance J. Clin. Invest. 96 1995 2339 2347
3. C.M. Blatteis Role of the OVLT in the febrile response to circulating pyrogens Prog. Brain Res. 91 1992 409 412
4. C.M. Blatteis, and E. Sehie Fever: how may circulating pyrogens signal the brain? News Physiol. Soc. 12 1997 1 9
5. C.D. Breder, C. Hazuka, T. Ghayur, C. Klug, M. Huginin, K. Yasuda, M. Teng, and C.B. Saper Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration Proc. Natl. Acad. Sci. U. S. A. 91 1994 11393 11397
6. M. Buttini, and H. Boddeke Peripheral lipopolysaccharide stimulation induces interleukin-1 beta messenger RNA in rat brain microglial cells Neuroscience 65 1995 523 530
7. C. Cao, K. Matsumura, M. Ozaki, and Y. Watanabe Lipopolysaccharide injected into the cerebral ventricle evokes fever through induction of cyclooxygenase-2 in brain endothelial cells J. Neurosci. 19 1999 716 725
8. T. Cartmell, C. Ball, A.F. Bristow, D. Mitchell, and S. Poole Endogenous interleukin-10 is required for the defervescence of fever evoked by local lipopolysaccharide-induced and Staphylococcus aureus-induced inflammation in rats J. Physiol. 549 2003 653 664
9. C.A. Dinarello Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed J. Endotoxin Res. 10 2004 201 222
10. S. Dokka, X. Shi, S. Leonard, L. Wang, V. Castranova, and Y. Rojanasakul Interleukin-10-mediated inhibition of free radical generation in macrophages Am. J. Physiol. Lung Cell. Mol. Physiol. 280 2001 L1196 L1202
11. J.K. Elmquist, C.D. Breder, J.E. Sherin, T.E. Scammell, W.F. Hickey, D. Dewitt, and C.B. Saper Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages J. Comp. Neurol. 381 1997 119 129
12. A. Ericsson, K.J. Kovacs, and P.E. Sawchenko A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons J. Neurosci. 14 1994 897 913
13. D.F. Fiorentino, A. Zlotnik, T.R. Mosmann, M. Howard, and A. O'Garra IL-10 inhibits cytokine production by activated macrophages J. Immunol. 147 1991 3815 3822
14. S. Gatti, and T. Bartfai Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: comparison with interleukin-1 family and interleukin-6 Brain Res. 624 1993 291 294
15. J.H. Hollis, M. Lemus, M.J. Evetts, and B.J. Oldfield Central interleukin-10 attenuates lipopolysaccharide-induced changes in food intake, energy expenditure and hypothalamic Fos expression Neuropharmacology 58 2010 730 738
16. M. Howard, and A. O'Garra Biological properties of interleukin 10 Immunol. Today 13 1992 198 200
17. W.T. Huang, M.T. Lin, and C.P. Chang An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever Neuropharmacology 50 2006 504 511
18. W.T. Huang, K.C. Niu, C.K. Chang, M.T. Lin, and C.P. Chang Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits Eur. J. Pharmacol. 593 2008 105 111
19. J.K. Jenkins, M. Malyak, and W.P. Arend The effects of interleukin-10 on interleukin-1 receptor antagonist and interleukin-1 beta production in human monocytes and neutrophils Lymphokine Cytokine Res. 13 1994 47 54
20. C.H. Kao, T.Y. Kao, W.T. Huang, and M.T. Lin Lipopolysaccharide- and glutamate-induced hypothalamic hydroxyl radical elevation and fever can be suppressed by N-methyl-d-aspartate-receptor antagonists J. Pharmacol. Sci. 104 2007 130 136
21. T.Y. Kao, W.T. Huang, C.P. Chang, and M.T. Lin Aspirin may exert its antipyresis by inhibiting the N-methyl-d-aspartate receptor-dependent hydroxyl radical pathways in the hypothalamus J. Pharmacol. Sci. 103 2007 293 298
22. J.J. Klir, J.L. McClellan, and M.J. Kluger Interleukin-1 beta causes the increase in anterior hypothalamic interleukin-6 during LPS-induced fever in rats Am. J. Physiol. 266 1994 R1845 R1848
23. M.J. Kluger Fever: role of pyrogens and cryogens Physiol. Rev. 71 1991 93 127
24. S. Laye, P. Parnet, E. Goujon, and R. Dantzer Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice Brain Res. Mol. Brain Res. 27 1994 157 162
25. A. Ledeboer, R. Binnekade, J.J. Breve, J.G. Bol, F.J. Tilders, and A.M. Van Dam Site-specific modulation of LPS-induced fever and interleukin-1 beta expression in rats by interleukin-10 Am. J. Physiol. Regul. Integr. Comp. Physiol. 282 2002 R1762 R1772
26. L.R. Leon, W. Kozak, K. Rudolph, and M.J. Kluger An antipyretic role for interleukin-10 in LPS fever in mice Am. J. Physiol. 276 1999 R81 R89
27. G. Luheshi, A.J. Miller, S. Brouwer, M.J. Dascombe, N.J. Rothwell, and S.J. Hopkins Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat Am. J. Physiol. 270 1996 E91 E95
28. K.W. Moore, R. de Waal Malefyt, R.L. Coffman, and A. O'Garra Interleukin-10 and the interleukin-10 receptor Annu. Rev. Immunol. 19 2001 683 765
29. F. Nava, G. Calapai, G. Facciola, S. Cuzzocrea, M.C. Marciano, A. De Sarro, and A.P. Caputi Effects of interleukin-10 on water intake, locomotory activity, and rectal temperature in rat treated with endotoxin Int. J. Immunopharmacol. 19 1997 31 38
30. K.C. Niu, W.T. Huang, M.T. Lin, and K.F. Huang Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits Eur. J. Pharmacol. 606 2009 240 245
31. A. Oberholzer, C. Oberholzer, and L.L. Moldawer Interleukin-10: a complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug Crit. Care Med. 30 2002 S58 S63
32. B.K. Pedersen, A. Steensberg, and P. Schjerling Exercise and interleukin-6 Curr. Opin. Hematol. 8 2001 137 141
33. D.M. Rennick, M.M. Fort, and N.J. Davidson Studies with IL-10-/- mice: an overview J. Leukoc. Biol. 61 1997 389 396
34. J. Roth, C.A. Conn, M.J. Kluger, and E. Zeisberger Kinetics of systemic and intrahypothalamic IL-6 and tumor necrosis factor during endotoxin fever in guinea pigs Am. J. Physiol. 265 1993 R653 R658
35. N.J. Rothwell Central effects of TNF alpha on thermogenesis and fever in the rat Biosci. Rep. 8 1988 345 352
36. N.J. Rothwell, N.J. Busbridge, R.A. Lefeuvre, A.J. Hardwick, J. Gauldie, and S.J. Hopkins Interleukin-6 is a centrally acting endogenous pyrogen in the rat Can. J. Physiol. Pharmacol. 69 1991 1465 1469
37. C.B. Saper, and C.D. Breder The neurologic basis of fever N. Engl. J. Med. 330 1994 1880 1886
38. C.H. Sawyer, J.W. Everett, and J.D. Green The rabbit diencephalon in stereotaxic coordinates J. Comp. Neurol. 101 1954 801 824
39. C.T. Simons, V.A. Kulchitsky, N. Sugimoto, L.D. Homer, M. Szekely, and A.A. Romanovsky Signaling the brain in systemic inflammation: which vagal branch is involved in fever genesis? Am. J. Physiol. 275 1998 R63 R68
40. K. Strle, J.H. Zhou, W.H. Shen, S.R. Broussard, R.W. Johnson, G.G. Freund, R. Dantzer, and K.W. Kelley Interleukin-10 in the brain Crit. Rev. Immunol. 21 2001 427 449
41. F.J. Tilders, R.H. DeRijk, A.M. Van Dam, V.A. Vincent, K. Schotanus, and J.H. Persoons Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: routes and intermediate signals Psychoneuroendocrinology 19 1994 209 232
42. C.C. Tsai, M.T. Lin, J.J. Wang, J.F. Liao, and W.T. Huang The antipyretic effects of baicalin in lipopolysaccharide-evoked fever in rabbits Neuropharmacology 51 2006 709 717
43. L. Vallieres, and S. Rivest Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta J. Neurochem. 69 1997 1668 1683
44. A.M. van Dam, M. Brouns, S. Louisse, and F. Berkenbosch Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: a pathway for the induction of non-specific symptoms of sickness? Brain Res. 588 1992 291 296
45. A.M. Van Dam, H.E. De Vries, J. Kuiper, F.J. Zijlstra, A.G. De Boer, F.J. Tilders, and F. Berkenbosch Interleukin-1 receptors on rat brain endothelial cells: a role in neuroimmune interaction? FASEB J. 10 1996 351 356
46. H. Ward, S. Vigues, S. Poole, and A.F. Bristow The rat interleukin 10 receptor: cloning and sequencing of cDNA coding for the alpha-chain protein sequence, and demonstration by western blotting of expression in the rat brain Cytokine 15 2001 237 240
47. H. Watanabe, and Y. Hayakawa Hypothalamic interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, mediate the endotoxin-induced suppression of the reproductive axis in rats Endocrinology 114 2003 4868 4875
48. Yang, C.Y., Lin, M.T., 2002. Oxidative stress in rats with heatstroke-induced cerebral ischemia. Stroke 33, 790-794.