Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits

European Journal of Pharmacology

Volumn 593, Issue 1-3, 2008, Pages 105-111

  Huang, Wu Tein ^a   Niu, Ko Chi ^b,c   Chang, Chen Kuei ^d,e   Lin, Mao Tsun ^b,c   Chang, Ching Ping ^b,c  

^a DIWAN COLLEGE OF MANAGEMENT   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d MACKAY MEMORIAL HOSPITAL   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Antipyresis; Curcumin; Fever; Glutamate; Hydroxyl radical; Lipopolysaccharide; Prostaglandin E2

Indexed keywords

CURCUMIN; GLUTAMIC ACID; HYDROXYL RADICAL; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANTIPYRETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; HYPOTHALAMUS; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CURCUMIN; DATA INTERPRETATION, STATISTICAL; DINOPROSTONE; FEVER; GLUTAMIC ACID; HYDROXYL RADICAL; HYPOTHALAMUS; INFLAMMATION; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; RABBITS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 49949097651     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.07.017     Document Type: Article

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