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Volumn 14, Issue 6, 2010, Pages 357-366

Biomarker assessment of the immunomodulator effect of atorvastatin in stable renal transplant recipients and hypercholesterolemic patients

Author keywords

Atorvastatin, general; Biomarkers; HMG CoA reductase inhibitors, general; Hypercholesterolaemia; Immunomodulators, general; Immunosuppression; Renal transplant; Tacrolimus, general; Transplantation

Indexed keywords

2 HYDROXYATORVASTATIN; ADENOSINE TRIPHOSPHATE; ATORVASTATIN; BIOLOGICAL MARKER; CHOLESTEROL; DRUG METABOLITE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 79551552062     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.2165/11539620-000000000-00000     Document Type: Article
Times cited : (5)

References (53)
  • 1
    • 60749131372 scopus 로고    scopus 로고
    • Statins in endothelial signaling and activation
    • Jacobson JR. Statins in endothelial signaling and activation. Antioxid Redox Signal 2009; 11 (4): 811-21
    • (2009) Antioxid Redox Signal , vol.11 , Issue.4 , pp. 811-821
    • Jacobson, J.R.1
  • 2
    • 33846639179 scopus 로고    scopus 로고
    • Statins and the vascular endothelial inflammatory response
    • Greenwood J, Mason JC. Statins and the vascular endothelial inflammatory response. Trends Immunol 2007; 28 (2): 88-98
    • (2007) Trends Immunol , vol.28 , Issue.2 , pp. 88-98
    • Greenwood, J.1    Mason, J.C.2
  • 3
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: From protein prenylation to immunomodulation
    • Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat Rev Immunol 2006; 6 (5): 358-70
    • (2006) Nat Rev Immunol , vol.6 , Issue.5 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 4
    • 25144522575 scopus 로고    scopus 로고
    • Toward immunomodulatory and antiinflammatory properties of statins
    • Arnaud C, Braunersreuther V, Mach F. Toward immunomodulatory and antiinflammatory properties of statins. Trends Cardiovasc Med 2005; 15 (6): 202-6
    • (2005) Trends Cardiovasc Med , vol.15 , Issue.6 , pp. 202-206
    • Arnaud, C.1    Braunersreuther, V.2    Mach, F.3
  • 5
    • 38049034068 scopus 로고    scopus 로고
    • Pleiotropic effects of statin therapy: Molecular mechanisms and clinical results
    • Wang CY, Liu PY, Liao JK. Pleiotropic effects of statin therapy: molecular mechanisms and clinical results. Trends Mol Med 2008; 14 (1): 37-44
    • (2008) Trends Mol Med , vol.14 , Issue.1 , pp. 37-44
    • Wang, C.Y.1    Liu, P.Y.2    Liao, J.K.3
  • 6
    • 33845627130 scopus 로고    scopus 로고
    • T helper 1/T helper 2 balance and HMG-CoA reductase inhibitors in acute coronary syndrome: Statins as immunomodulatory agents?
    • Shimada K, Park JK, Daida H. T helper 1/T helper 2 balance and HMG-CoA reductase inhibitors in acute coronary syndrome: statins as immunomodulatory agents? Eur Heart J 2006; 27 (24): 2916-8
    • (2006) Eur Heart J , vol.27 , Issue.24 , pp. 2916-2918
    • Shimada, K.1    Park, J.K.2    Daida, H.3
  • 7
    • 18444364236 scopus 로고    scopus 로고
    • Cholesterol-independent effects of statins in inflammation, immunomodulation and atherosclerosis
    • Arnaud C, Veillard NR, Mach F. Cholesterol-independent effects of statins in inflammation, immunomodulation and atherosclerosis. Curr Drug Targets Cardiovasc Haematol Disord 2005; 5 (2): 127-34
    • (2005) Curr Drug Targets Cardiovasc Haematol Disord , vol.5 , Issue.2 , pp. 127-134
    • Arnaud, C.1    Veillard, N.R.2    MacH, F.3
  • 8
    • 0036583733 scopus 로고    scopus 로고
    • Statins as immunomodulators
    • Mach F. Statins as immunomodulators. Transpl Immunol 2002; 9 (2-4): 197-200
    • (2002) Transpl Immunol , vol.9 , Issue.2-4 , pp. 197-200
    • MacH, F.1
  • 9
    • 21544482024 scopus 로고    scopus 로고
    • Statins affect cell-surface expression ofmajor histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains
    • Kuipers HF, Biesta PJ, Groothuis TA, et al. Statins affect cell-surface expression ofmajor histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains. Hum Immunol 2005; 66 (6): 653-65
    • (2005) Hum Immunol , vol.66 , Issue.6 , pp. 653-665
    • Kuipers, H.F.1    Biesta, P.J.2    Groothuis, T.A.3
  • 10
    • 0034948339 scopus 로고    scopus 로고
    • Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
    • Weitz-Schmidt G, Welzenbach K, Brinkmann V, et al. Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nat Med 2001; 7 (6): 687-92
    • (2001) Nat Med , vol.7 , Issue.6 , pp. 687-692
    • Weitz-Schmidt, G.1    Welzenbach, K.2    Brinkmann, V.3
  • 11
    • 70349258349 scopus 로고    scopus 로고
    • Immunomodulation by statins: Mechanisms and potential impact on autoimmune diseases
    • Chow SC. Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases. Arch Immunol Ther Exp (Warsz) 2009; 57 (4): 243-51
    • (2009) Arch Immunol Ther Exp (Warsz) , vol.57 , Issue.4 , pp. 243-251
    • Chow, S.C.1
  • 12
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004; 109 (21 Suppl. 1): II18-26
    • (2004) Circulation , vol.109 , Issue.21 SUPPL. 1
    • Schonbeck, U.1    Libby, P.2
  • 13
    • 51449089047 scopus 로고    scopus 로고
    • Inflammatory lipids as a target for therapy in the rheumatic diseases
    • McMahon M, Brahn E. Inflammatory lipids as a target for therapy in the rheumatic diseases. Expert Opin Investig Drugs 2008; 17 (8): 1213-24
    • (2008) Expert Opin Investig Drugs , vol.17 , Issue.8 , pp. 1213-1224
    • McMahon, M.1    Brahn, E.2
  • 14
    • 1342282244 scopus 로고    scopus 로고
    • A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma
    • McKay A, Leung BP, McInnes IB, et al. A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. J Immunol 2004; 172 (5): 2903-8
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2903-2908
    • McKay, A.1    Leung, B.P.2    McInnes, I.B.3
  • 15
    • 0037038402 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
    • Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature 2002; 420 (6911): 78-84
    • (2002) Nature , vol.420 , Issue.6911 , pp. 78-84
    • Youssef, S.1    Stuve, O.2    Patarroyo, J.C.3
  • 16
    • 47249120828 scopus 로고    scopus 로고
    • Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus
    • Graham KL, Lee LY, Higgins JP, et al. Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus. Arthritis Rheum 2008; 58 (7): 2098-104
    • (2008) Arthritis Rheum , vol.58 , Issue.7 , pp. 2098-2104
    • Graham, K.L.1    Lee, L.Y.2    Higgins, J.P.3
  • 18
    • 23944472398 scopus 로고    scopus 로고
    • Cardiovascular risk and renal transplantation: Post hoc analyses of the Assessment of Lescol in Renal Transplantation (ALERT) study
    • Jardine AG, Fellstrom B, Logan JO, et al. Cardiovascular risk and renal transplantation: post hoc analyses of the Assessment of Lescol in Renal Transplantation (ALERT) study. Am J Kidney Dis 2005; 46 (3): 529-36
    • (2005) Am J Kidney Dis , vol.46 , Issue.3 , pp. 529-536
    • Jardine, A.G.1    Fellstrom, B.2    Logan, J.O.3
  • 19
    • 10744229858 scopus 로고    scopus 로고
    • Effect of fluvastatin on cardiac outcomes in renal transplant recipients: ZA multicentre, randomised, placebocontrolled trial
    • Holdaas H, Fellstrom B, Jardine AG, et al. Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebocontrolled trial. Lancet 2003; 361 (9374): 2024-31
    • (2003) Lancet , vol.361 , Issue.9374 , pp. 2024-2031
    • Holdaas, H.1    Fellstrom, B.2    Jardine, A.G.3
  • 20
    • 56049101353 scopus 로고    scopus 로고
    • Minimization of immunosuppression: Transplant immunology
    • Patel J, Kobashigawa JA. Minimization of immunosuppression: transplant immunology. Transpl Immunol 2008; 20 (1-2): 48-54
    • (2008) Transpl Immunol , vol.20 , Issue.1-2 , pp. 48-54
    • Patel, J.1    Kobashigawa, J.A.2
  • 21
    • 67649321264 scopus 로고    scopus 로고
    • Kidney transplantation: The ideal immunosuppression regimen
    • Yabu JM, Vincenti F. Kidney transplantation: the ideal immunosuppression regimen. Adv Chronic Kidney Dis 2009; 16 (4): 226-33
    • (2009) Adv Chronic Kidney Dis , vol.16 , Issue.4 , pp. 226-233
    • Yabu, J.M.1    Vincenti, F.2
  • 22
    • 57349116387 scopus 로고    scopus 로고
    • Calcineurin inhibitor minimization protocols in liver transplantation
    • Farkas SA, Schnitzbauer AA, Kirchner G, et al. Calcineurin inhibitor minimization protocols in liver transplantation. Transpl Int 2009; 22 (1): 49-60
    • (2009) Transpl Int , vol.22 , Issue.1 , pp. 49-60
    • Farkas, S.A.1    Schnitzbauer, A.A.2    Kirchner, G.3
  • 23
    • 57349170379 scopus 로고    scopus 로고
    • Minimization of steroids in liver transplantation
    • Lerut J, Bonaccorsi-Riani E, Finet P, et al. Minimization of steroids in liver transplantation. Transpl Int 2009; 22 (1): 2-19
    • (2009) Transpl Int , vol.22 , Issue.1 , pp. 2-19
    • Lerut, J.1    Bonaccorsi-Riani, E.2    Finet, P.3
  • 24
    • 57249109878 scopus 로고    scopus 로고
    • Statins induce immunosuppressive effect on heterotopic limb allografts in rat through inhibiting T cell activation and proliferation
    • Nie C, Yang D, Liu G, et al. Statins induce immunosuppressive effect on heterotopic limb allografts in rat through inhibiting T cell activation and proliferation. Eur J Pharmacol 2009; 602 (1): 168-75
    • (2009) Eur J Pharmacol , vol.602 , Issue.1 , pp. 168-175
    • Nie, C.1    Yang, D.2    Liu, G.3
  • 25
    • 27244434795 scopus 로고    scopus 로고
    • In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells
    • Bessler H, Salman H, Bergman M, et al. In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells. Clin Immunol 2005; 117 (1): 73-7
    • (2005) Clin Immunol , vol.117 , Issue.1 , pp. 73-77
    • Bessler, H.1    Salman, H.2    Bergman, M.3
  • 26
    • 34249310984 scopus 로고    scopus 로고
    • Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction
    • Takahashi HK, Iwagaki H, Yagi T, et al. Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. Clin Immunol 2007; 123 (3): 324-32
    • (2007) Clin Immunol , vol.123 , Issue.3 , pp. 324-332
    • Takahashi, H.K.1    Iwagaki, H.2    Yagi, T.3
  • 27
    • 0036766463 scopus 로고    scopus 로고
    • Pharmacodynamics of mycophenolate mofetil after heart transplantation: New mechanisms of action and correlations with histologic severity of graft rejection
    • Barten MJ, van GT, Gummert JF, et al. Pharmacodynamics of mycophenolate mofetil after heart transplantation: new mechanisms of action and correlations with histologic severity of graft rejection. Am J Transplant 2002; 2 (8): 719-32
    • (2002) Am J Transplant , vol.2 , Issue.8 , pp. 719-732
    • Barten, M.J.1    Van Gt Gummert, J.F.2
  • 28
    • 10744226204 scopus 로고    scopus 로고
    • Pharmacodynamic approach to immunosuppressive therapies using calcineurin inhibitors and mycophenolate mofetil
    • Millán O, Brunet M, Campistol JM, et al. Pharmacodynamic approach to immunosuppressive therapies using calcineurin inhibitors and mycophenolate mofetil. Clin Chem 2003; 49 (11): 1891-9
    • (2003) Clin Chem , vol.49 , Issue.11 , pp. 1891-1899
    • Millán, O.1    Brunet, M.2    Campistol, J.M.3
  • 29
    • 67651115805 scopus 로고    scopus 로고
    • The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: The SYMPHONY pharmacokinetic substudy
    • Grinyo JM, Ekberg H, Mamelok RD, et al. The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the SYMPHONY pharmacokinetic substudy. Nephrol Dial Transplant 2009; 24 (7): 2269-76
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.7 , pp. 2269-2276
    • Grinyo, J.M.1    Ekberg, H.2    Mamelok, R.D.3
  • 30
    • 34548392743 scopus 로고    scopus 로고
    • T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy
    • Brunet M, Campistol JM, Diekmann F, et al. T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy. Mol Diagn Ther 2007; 11 (4): 247-56
    • (2007) Mol Diagn Ther , vol.11 , Issue.4 , pp. 247-256
    • Brunet, M.1    Campistol, J.M.2    Diekmann, F.3
  • 31
    • 12144290499 scopus 로고    scopus 로고
    • Clinical practice guidelines for managing dyslipidemias in kidney transplant patients: A report from the Managing Dyslipidemias in Chronic Kidney Disease Work Group of the National Kidney Foundation Kidney Disease Outcomes Quality Initiative
    • Kasiske B, Cosio FG, Beto J, et al. Clinical practice guidelines for managing dyslipidemias in kidney transplant patients: a report from the Managing Dyslipidemias in Chronic Kidney Disease Work Group of the National Kidney Foundation Kidney Disease Outcomes Quality Initiative. Am J Transplant 2004; 4 Suppl. 7: 13-53
    • (2004) Am J Transplant , vol.4 , Issue.SUPPL. 7 , pp. 13-53
    • Kasiske, B.1    Cosio, F.G.2    Beto, J.3
  • 32
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285 (19): 2486-97
    • (2001) JAMA , vol.285 , Issue.19 , pp. 2486-2497
  • 33
    • 0036267333 scopus 로고    scopus 로고
    • Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood
    • Streit F, Armstrong VW, Oellerich M. Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood. Clin Chem 2002; 48 (6 Pt 1): 955-8
    • (2002) Clin Chem , vol.48 , Issue.6 PART 1 , pp. 955-958
    • Streit, F.1    Armstrong, V.W.2    Oellerich, M.3
  • 34
    • 33644616547 scopus 로고    scopus 로고
    • Sequential determination of pharmacokinetics and pharmacodynamics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil
    • Brunet M, Cirera I, Martorell J, et al. Sequential determination of pharmacokinetics and pharmacodynamics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil. Transplantation 2006; 81 (4): 541-6
    • (2006) Transplantation , vol.81 , Issue.4 , pp. 541-546
    • Brunet, M.1    Cirera, I.2    Martorell, J.3
  • 35
    • 67650945043 scopus 로고    scopus 로고
    • Determination of atorvastatin and its metabolite ortho- hydroxyatorvastatin in human plasma by on-line anion-exchange solid-phase extraction and liquid chromatography tandem mass spectrometry
    • Guillén D, Cofán F, Ros E, et al. Determination of atorvastatin and its metabolite ortho-hydroxyatorvastatin in human plasma by on-line anion-exchange solid-phase extraction and liquid chromatography tandem mass spectrometry. Anal Bioanal Chem 2009; 394 (6): 1687-96
    • (2009) Anal Bioanal Chem , vol.394 , Issue.6 , pp. 1687-1696
    • Guillén, D.1    Cofán, F.2    Ros, E.3
  • 36
    • 4444318682 scopus 로고    scopus 로고
    • Optimum culture conditions for specific and nonspecific activation of whole blood and PBMC for intracellular cytokine assessment by flow cytometry
    • Godoy-Ramirez K, Franck K, Mahdavifar S, et al. Optimum culture conditions for specific and nonspecific activation of whole blood and PBMC for intracellular cytokine assessment by flow cytometry. J Immunol Methods 2004; 292 (1-2): 1-15
    • (2004) J Immunol Methods , vol.292 , Issue.1-2 , pp. 1-15
    • Godoy-Ramirez, K.1    Franck, K.2    Mahdavifar, S.3
  • 37
    • 9344254902 scopus 로고    scopus 로고
    • The effect of pravastatin on acute rejection after kidney transplantation: A pilot study
    • Katznelson S,Wilkinson AH, Kobashigawa JA, et al. The effect of pravastatin on acute rejection after kidney transplantation: a pilot study. Transplantation 1996; 61 (10): 1469-74
    • (1996) Transplantation , vol.61 , Issue.10 , pp. 1469-1474
    • Katznelson Swilkinson, A.H.1    Kobashigawa, J.A.2
  • 38
    • 0342803869 scopus 로고    scopus 로고
    • Comparison of the effects of simvastatin and pravastatin on acute rejection episodes in renal transplant patients
    • Tuncer M, Suleymanlar G, Ersoy FF, et al. Comparison of the effects of simvastatin and pravastatin on acute rejection episodes in renal transplant patients. Transplant Proc 2000; 32 (3): 622-5
    • (2000) Transplant Proc , vol.32 , Issue.3 , pp. 622-625
    • Tuncer, M.1    Suleymanlar, G.2    Ersoy, F.F.3
  • 39
    • 0034910647 scopus 로고    scopus 로고
    • The effects of lipidlowering agents on acute renal allograft rejection
    • Kasiske BL, Heim-Duthoy KL, Singer GG, et al. The effects of lipidlowering agents on acute renal allograft rejection. Transplantation 2001; 72(2): 223-7
    • (2001) Transplantation , vol.72 , Issue.2 , pp. 223-227
    • Kasiske, B.L.1    Heim-Duthoy, K.L.2    Singer, G.G.3
  • 40
    • 0035023644 scopus 로고    scopus 로고
    • Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection
    • Sahu K, Sharma R, Gupta A, et al. Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection. Clin Transplant 2001; 15 (3): 173-5
    • (2001) Clin Transplant , vol.15 , Issue.3 , pp. 173-175
    • Sahu, K.1    Sharma, R.2    Gupta, A.3
  • 41
    • 0031847115 scopus 로고    scopus 로고
    • Effect of itraconazole on the pharmacokinetics of atorvastatin
    • Kantola T, Kivisto KT, Neuvonen PJ. Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 1998; 64 (1): 58-65
    • (1998) Clin Pharmacol Ther , vol.64 , Issue.1 , pp. 58-65
    • Kantola, T.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 42
    • 22144450683 scopus 로고    scopus 로고
    • Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LCtandem MS
    • Hermann M, Christensen H, Reubsaet JL. Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LCtandem MS. Anal Bioanal Chem 2005; 382 (5): 1242-9
    • (2005) Anal Bioanal Chem , vol.382 , Issue.5 , pp. 1242-1249
    • Hermann, M.1    Christensen, H.2    Reubsaet, J.L.3
  • 43
    • 4744370480 scopus 로고    scopus 로고
    • Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients
    • Hermann M, Asberg A, Christensen H, et al. Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients. Clin Pharmacol Ther 2004; 76 (4): 388-91
    • (2004) Clin Pharmacol Ther , vol.76 , Issue.4 , pp. 388-391
    • Hermann, M.1    Asberg, A.2    Christensen, H.3
  • 44
    • 0030870919 scopus 로고    scopus 로고
    • Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin
    • Stern RH, Yang BB, Horton M, et al. Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin. J Clin Pharmacol 1997; 37 (9): 816-9
    • (1997) J Clin Pharmacol , vol.37 , Issue.9 , pp. 816-819
    • Stern, R.H.1    Yang, B.B.2    Horton, M.3
  • 45
    • 33748690103 scopus 로고    scopus 로고
    • Assessing relative risks of infection and rejection: A meta-analysis using an immune function assay
    • Kowalski RJ, Post DR, Mannon RB, et al. Assessing relative risks of infection and rejection: a meta-analysis using an immune function assay. Transplantation 2006; 82 (5): 663-8
    • (2006) Transplantation , vol.82 , Issue.5 , pp. 663-668
    • Kowalski, R.J.1    Post, D.R.2    Mannon, R.B.3
  • 46
    • 70349126317 scopus 로고    scopus 로고
    • Is the intracellular ATP concentration of CD4+ T-cells a predictive biomarker of immune status in stable transplant recipients?
    • Millán O, Sanchez-Fueyo A, Rimola A, et al. Is the intracellular ATP concentration of CD4+ T-cells a predictive biomarker of immune status in stable transplant recipients? Transplantation 2009; 88 (3 Suppl.): S78-84
    • (2009) Transplantation , vol.88 , Issue.3 SUPPL.
    • Millán, O.1    Sanchez-Fueyo, A.2    Rimola, A.3
  • 47
    • 50249141261 scopus 로고    scopus 로고
    • Cylex ImmuKnow assay levels are lower in lung transplant recipients with infection
    • Bhorade SM, Janata K, Vigneswaran WT, et al. Cylex ImmuKnow assay levels are lower in lung transplant recipients with infection. J Heart Lung Transplant 2008; 27 (9): 990-4
    • (2008) J Heart Lung Transplant , vol.27 , Issue.9 , pp. 990-994
    • Bhorade, S.M.1    Janata, K.2    Vigneswaran, W.T.3
  • 48
    • 58149159560 scopus 로고    scopus 로고
    • Assessment of the Cylex ImmuKnow cell function assay in pediatric heart transplant patients
    • Rossano JW, Denfield SW, Kim JJ, et al. Assessment of the Cylex ImmuKnow cell function assay in pediatric heart transplant patients. J Heart Lung Transplant 2009; 28 (1): 26-31
    • (2009) J Heart Lung Transplant , vol.28 , Issue.1 , pp. 26-31
    • Rossano, J.W.1    Denfield, S.W.2    Kim, J.J.3
  • 49
    • 67649588841 scopus 로고    scopus 로고
    • Experience with immune monitoring in lung transplant recipients: Correlation of low immune function with infection
    • Husain S, Raza K, Pilewski JM, et al. Experience with immune monitoring in lung transplant recipients: correlation of low immune function with infection. Transplantation 2009; 87 (12): 1852-7
    • (2009) Transplantation , vol.87 , Issue.12 , pp. 1852-1857
    • Husain, S.1    Raza, K.2    Pilewski, J.M.3
  • 50
    • 67651049212 scopus 로고    scopus 로고
    • The impact of EBV load on T-cell immunity in pediatric thoracic transplant recipients
    • Macedo C, Zeevi A, Bentlejewski C, et al. The impact of EBV load on T-cell immunity in pediatric thoracic transplant recipients. Transplantation 2009; 88 (1): 123-8
    • (2009) Transplantation , vol.88 , Issue.1 , pp. 123-128
    • MacEdo, C.1    Zeevi, A.2    Bentlejewski, C.3
  • 51
    • 3042651960 scopus 로고    scopus 로고
    • Defective inhibition of peripheral CD8+ T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection
    • Boleslawski E, Conti F, Sanquer S, et al. Defective inhibition of peripheral CD8+ T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection. Transplantation 2004; 77 (12): 1815-20
    • (2004) Transplantation , vol.77 , Issue.12 , pp. 1815-1820
    • Boleslawski, E.1    Conti, F.2    Sanquer, S.3
  • 52
    • 34249017360 scopus 로고    scopus 로고
    • Effects of simvastatin on human T cells in vivo
    • Cherfan P, Tompa A, WikbyA, et al. Effects of simvastatin on human T cells in vivo. Atherosclerosis 2007; 193 (1): 186-92
    • (2007) Atherosclerosis , vol.193 , Issue.1 , pp. 186-192
    • Cherfan, P.1    Wikbya, T.A.2
  • 53
    • 40949143105 scopus 로고    scopus 로고
    • The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells
    • Mausner-Fainberg K, Luboshits G, Mor A, et al. The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. Atherosclerosis 2008; 197 (2): 829-39
    • (2008) Atherosclerosis , vol.197 , Issue.2 , pp. 829-839
    • Mausner-Fainberg, K.1    Luboshits, G.2    Mor, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.