Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood

Clinical Chemistry

Volumn 48, Issue 6, 2002, Pages 955-958

  Streit, Frank ^a   Armstrong, Victor William ^a   Oellerich, Michael ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; EVEROLIMUS; RAPAMYCIN; TACROLIMUS;

ACCURACY; ARTICLE; BLOOD ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; LIQUID CHROMATOGRAPHY; QUANTITATIVE ASSAY; TANDEM MASS SPECTROMETRY;

EID: 0036267333     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/48.6.955     Document Type: Article

References (18)

1. 1-arresting rapamycin-receptor complex
2. Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection
3. SDZ RAD, a new rapamycin derivative: Synergism with cyclosporine
4. Sirolimus-tacrolimus combination immunosuppression
5. Clinical pharmacokinetics of sirolimus
6. Lake Louise Consensus Conference on cyclosporin monitoring in organ transplantation: Report of the consensus panel
7. Impact of absorption profiling on efficacy and safety of cyclosporin therapy in transplant recipients
8. New approaches to cyclosporine monitoring raise further concerns about analytical techniques
9. Orthotopic liver transplantation using low-dose tacrolimus and sirolimus
10. LC/ESI-MS allows simultaneous and specific quantification of SDZ RAD and cyclosporine, including groups of their metabolites in human blood
11. Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: Immunosuppressants
12. Simultaneous quantification of tacrolimus and sirolimus, in human blood, by high-performance liquid chromatography-tandem mass spectrometry
13. Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography-tandem mass-spectrometry
14. High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood
15. Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): A critical overview of performance characteristics and comparison with HPLC
16. Performance and specificity of monoclonal immunoassays for cyclosporine monitoring: How specific is specific?
17. Modified pentamer formation assay for measurement of tacrolimus and its active metabolites: Comparison with liquid chromatography-tandem mass spectrometry and microparticle enzyme-linked immunoassay (MEIA-II)