Intrachromosomal mitotic nonallelic homologous recombination is the major molecular mechanism underlying type-2 NF1 deletions

Human Mutation

Volumn 31, Issue 10, 2010, Pages 1163-1173

  Roehl, Angelika C ^a   Vogt, Julia ^a   Mussotter, Tanja ^a   Zickler, Antje N ^a   Spöti, Helene ^a   Högel, Josef ^a   Chuzhanova, Nadia A ^b   Wimmer, Katharina ^c   Kluwe, Lan ^d   Mautner, Victor Felix ^d   Cooper, David N ^e   Kehrer Sawatzki, Hildegard ^a  

^a UNIVERSITY OF ULM   (Germany)

^b NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Alu; Microdeletion; Mitotic nonallelic homologous recombination; NAHR; Neurofibromatosis type 1; NF1; Non B DNA; Tumorigenesis

Indexed keywords

DOUBLE STRANDED DNA; MEMBRANE PROTEIN; NF1 TYPE 2 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; MICROSATELLITE DNA; NEUROFIBROMIN; NUCLEAR PROTEIN; SUZ12 PROTEIN, HUMAN;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; DNA BASE COMPOSITION; FEMALE; GENE DELETION; GENE LOCATION; GERMLINE MICRONUCLEUS; HOMOLOGOUS RECOMBINATION; HUMAN; INTRACHROMOSOMAL NONALLELIC HOMOLOGOUS RECOMBINATION; MALE; MICROARRAY ANALYSIS; MICROSATELLITE MARKER; MOLECULAR MECHANICS; PRIORITY JOURNAL; PSEUDOGENE; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGY; CHROMOSOME 17; DNA MICROARRAY; GENETIC RECOMBINATION; GENETICS; METHODOLOGY; MITOSIS; NEUROFIBROMATOSIS; TUMOR SUPPRESSOR GENE;

CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 17; COMPUTATIONAL BIOLOGY; GENES, NEUROFIBROMATOSIS 1; HUMANS; MICROSATELLITE REPEATS; MITOSIS; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC; SEQUENCE DELETION;

EID: 79551527960     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21340     Document Type: Article

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