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Volumn 39, Issue 2, 2011, Pages 720-728

Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; PLATINUM COMPLEX; TRIPLATIN TETRANITRATE;

EID: 79551483886     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq803     Document Type: Article
Times cited : (22)

References (31)
  • 1
    • 0036519363 scopus 로고    scopus 로고
    • DNA and its associated processes as targets for cancer therapy
    • Hurley, L.H. (2002) DNA and its associated processes as targets for cancer therapy. Nature Rev. Cancer, 2, 188-200.
    • (2002) Nature Rev. Cancer , vol.2 , pp. 188-200
    • Hurley, L.H.1
  • 2
    • 0035819940 scopus 로고    scopus 로고
    • Catalysis and inhibition of ligand substitution in palladium(II) square-planar complexes: Effects of DNA
    • Cusumano, M., DiPietro, M.L., Giannetto, A., Messina, M.A. and Romano, F. (2001) Catalysis and inhibition of ligand substitution in palladium(II) square-planar complexes: Effects of DNA. J. Am. Chem. Soc., 123, 1914-1919.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 1914-1919
    • Cusumano, M.1    Dipietro, M.L.2    Giannetto, A.3    Messina, M.A.4    Romano, F.5
  • 3
    • 0037222396 scopus 로고    scopus 로고
    • The nature of the DNA template (single-versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug
    • Davies, M.S., Berners-Price, S.J., Cox, J.W. and Farrell, N. (2003) The nature of the DNA template (single-versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug. Chem. Commun., 122-123.
    • (2003) Chem. Commun. , pp. 122-123
    • Davies, M.S.1    Berners-Price, S.J.2    Cox, J.W.3    Farrell, N.4
  • 4
    • 0025234552 scopus 로고
    • Identification and characterization of a novel linkage isomerization in the reaction of trans-diamminedichloroplatinum(II) with 50-d (TCTA CGCGTTCT)
    • Comess, K.M., Costello, C.E. and Lippard, S.J. (1990) Identification and characterization of a novel linkage isomerization in the reaction of trans-diamminedichloroplatinum(II) with 50-d (TCTA CGCGTTCT). Biochemistry, 29, 2102-2110.
    • (1990) Biochemistry , vol.29 , pp. 2102-2110
    • Comess, K.M.1    Costello, C.E.2    Lippard, S.J.3
  • 5
    • 0342467693 scopus 로고    scopus 로고
    • Rearrangement of interstrand cross-links into intrastrand cross-links in cis-diamminedichloroplatinum(II)-modified DNA
    • Perez, C., Leng, M. and Malinge, J.M. (1997) Rearrangement of interstrand cross-links into intrastrand cross-links in cis-diamminedichloroplatinum(II)- modified DNA. Nucleic Acids Res., 25, 896-903.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 896-903
    • Perez, C.1    Leng, M.2    Malinge, J.M.3
  • 6
    • 0034021505 scopus 로고    scopus 로고
    • Transplatin-modified oligonucleotides as modulators of gene expression
    • Giraud-Panis, M.-J. and Leng, M. (2000) Transplatin-modified oligonucleotides as modulators of gene expression. Pharmacol. Therapeutics, 85, 175-181.
    • (2000) Pharmacol. Therapeutics , vol.85 , pp. 175-181
    • Giraud-Panis, M.-J.1    Leng, M.2
  • 7
    • 34247614959 scopus 로고    scopus 로고
    • Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin
    • Chvalova, K., Brabec, V. and Kasparkova, J. (2007) Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin. Nucleic Acids Res., 35, 1812-1821.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 1812-1821
    • Chvalova, K.1    Brabec, V.2    Kasparkova, J.3
  • 8
    • 0030031440 scopus 로고    scopus 로고
    • Photoreactivity of platinum(II) in cisplatin-modified DNA affords specific cross-links to HMG domain proteins
    • Kane, S.A. and Lippard, S.J. (1996) Photoreactivity of platinum(II) in cisplatin-modified DNA affords specific cross-links to HMG domain proteins. Biochemistry, 35, 2180-2188.
    • (1996) Biochemistry , vol.35 , pp. 2180-2188
    • Kane, S.A.1    Lippard, S.J.2
  • 9
    • 3042703868 scopus 로고    scopus 로고
    • Polynuclear platinum drugs
    • Sigel, A. and Sigel, H. (eds) Marcel Dekker Inc., New York, Basel
    • Farrell, N. (2004) Polynuclear platinum drugs. In Sigel, A. and Sigel, H. (eds), Metal Ions in Biological Systems, Vol. 42. Marcel Dekker Inc., New York, Basel, pp. 251-296.
    • (2004) Metal Ions in Biological Systems , vol.42 , pp. 251-296
    • Farrell, N.1
  • 10
    • 0026803014 scopus 로고
    • Activation of the trans geometry in platinum antitumor complexes: A survey of the cytotoxicity of trans complexes containing planar ligands in murine-L1210 and human tumor panels and studies on their mechanism of action
    • Farrell, N., Kelland, L.R., Roberts, J.D. and Van Beusichem, M. (1992) Activation of the trans geometry in platinum antitumor complexes: a survey of the cytotoxicity of trans complexes containing planar ligands in murine-L1210 and human tumor panels and studies on their mechanism of action. Cancer Res., 52, 5065-5072.
    • (1992) Cancer Res. , vol.52 , pp. 5065-5072
    • Farrell, N.1    Kelland, L.R.2    Roberts, J.D.3    Van Beusichem, M.4
  • 11
    • 2542422438 scopus 로고    scopus 로고
    • Structure recognition, and processing of cisplatin-DNA adducts
    • Jamieson, E.R. and Lippard, S.J. (1999) Structure, recognition, and processing of cisplatin-DNA adducts. Chem. Rev., 99, 2467-2498.
    • (1999) Chem. Rev. , vol.99 , pp. 2467-2498
    • Jamieson, E.R.1    Lippard, S.J.2
  • 12
    • 18244379333 scopus 로고    scopus 로고
    • Cellular processing of platinum anticancer drugs
    • Wang, D. and Lippard, S.J. (2005) Cellular processing of platinum anticancer drugs. Nature Rev. Drug Discov., 4, 307-320.
    • (2005) Nature Rev. Drug Discov. , vol.4 , pp. 307-320
    • Wang, D.1    Lippard, S.J.2
  • 13
    • 0037060704 scopus 로고    scopus 로고
    • Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [{trans-PtCl(NH3) 2} 2{m-trans-Pt(NH3)2(NH2(CH2)6NH2) 2}]4+ (BBR3464)
    • Davies, M.S., Thomas, D.S., Hegmans, A., Berners-Price, S.J. and Farrell, N. (2002) Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [{trans-PtCl(NH3)2}2{m-trans-Pt(NH3) 2(NH2(CH2)6NH2)2}]4+ (BBR3464). Inorg. Chem., 41, 1101-1109.
    • (2002) Inorg. Chem. , vol.41 , pp. 1101-1109
    • Davies, M.S.1    Thomas, D.S.2    Hegmans, A.3    Berners-Price, S.J.4    Farrell, N.5
  • 14
    • 0036933447 scopus 로고    scopus 로고
    • A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
    • McGregor, T.D., Hegmans, A., Kasparkova, J., Neplechova, K., Novakova, O., Penazova, H., Vrana, O., Brabec, V. and Farrell, N. (2002) A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464. J. Biol. Inorg. Chem., 7, 397-404.
    • (2002) J. Biol. Inorg. Chem. , vol.7 , pp. 397-404
    • McGregor, T.D.1    Hegmans, A.2    Kasparkova, J.3    Neplechova, K.4    Novakova, O.5    Penazova, H.6    Vrana, O.7    Brabec, V.8    Farrell, N.9
  • 15
    • 0040610786 scopus 로고    scopus 로고
    • DNA modifications by a novel bifunctional trinuclear platinum Phase i anticancer agent
    • Brabec, V., Kasparkova, J., Vrana, O., Novakova, O., Cox, J.W., Qu, Y. and Farrell, N. (1999) DNA modifications by a novel bifunctional trinuclear platinum Phase I anticancer agent. Biochemistry, 38, 6781-6790.
    • (1999) Biochemistry , vol.38 , pp. 6781-6790
    • Brabec, V.1    Kasparkova, J.2    Vrana, O.3    Novakova, O.4    Cox, J.W.5    Qu, Y.6    Farrell, N.7
  • 16
    • 1242297016 scopus 로고    scopus 로고
    • Long range 1, 4 and 1, 6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove pre-association affects kinetics and mechanism of cross-link formation as well as adduct structure
    • Hegmans, A., Berners-Price, S.J., Davies, M.S., Thomas, D., Humphreys, A. and Farrell, N. (2004) Long range 1, 4 and 1, 6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove pre-association affects kinetics and mechanism of cross-link formation as well as adduct structure. J. Am. Chem. Soc., 126, 2166-2180.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 2166-2180
    • Hegmans, A.1    Berners-Price, S.J.2    Davies, M.S.3    Thomas, D.4    Humphreys, A.5    Farrell, N.6
  • 17
    • 0037073777 scopus 로고    scopus 로고
    • DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation recognition by high mobility group domain proteins, and nucleotide excision repair
    • Kasparkova, J., Zehnulova, J., Farrell, N. and Brabec, V. (2002) DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. J. Biol. Chem., 277, 48076-48086.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48076-48086
    • Kasparkova, J.1    Zehnulova, J.2    Farrell, N.3    Brabec, V.4
  • 18
    • 0035933825 scopus 로고    scopus 로고
    • Conformation recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464
    • Zehnulova, J., Kasparkova, J., Farrell, N. and Brabec, V. (2001) Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464. J. Biol. Chem., 276, 22191-22199.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22191-22199
    • Zehnulova, J.1    Kasparkova, J.2    Farrell, N.3    Brabec, V.4
  • 19
    • 70349267819 scopus 로고    scopus 로고
    • Factors affecting DNA-DNA interstrand cross-links in the antiparallel 30-30 sense: A comparison with the 50-50 directional isomer
    • Ruhayel, R.A., Moniodis, J.J., Yang, X., Kasparkova, J., Brabec, V., Berners-Price, S.J. and Farrell, N.P. (2009) Factors affecting DNA-DNA interstrand cross-links in the antiparallel 30-30 sense: A comparison with the 50-50 directional isomer. Chem. Eur. J., 15, 9365-9374.
    • (2009) Chem. Eur. J. , vol.15 , pp. 9365-9374
    • Ruhayel, R.A.1    Moniodis, J.J.2    Yang, X.3    Kasparkova, J.4    Brabec, V.5    Berners-Price, S.J.6    Farrell, N.P.7
  • 20
    • 0035925158 scopus 로고    scopus 로고
    • Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: Evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers
    • Cox, J.W., Berners-Price, S., Davies, M.S., Qu, Y. and Farrell, N. (2001) Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: Evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers. J. Am. Chem. Soc., 123, 1316-1326.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 1316-1326
    • Cox, J.W.1    Berners-Price, S.2    Davies, M.S.3    Qu, Y.4    Farrell, N.5
  • 21
    • 0026992557 scopus 로고
    • Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding
    • Brabec, V., Reedijk, J. and Leng, M. (1992) Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding. Biochemistry, 31, 12397-12402.
    • (1992) Biochemistry , vol.31 , pp. 12397-12402
    • Brabec, V.1    Reedijk, J.2    Leng, M.3
  • 22
    • 0034717289 scopus 로고    scopus 로고
    • Sequence specificity conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes
    • Kasparkova, J., Farrell, N. and Brabec, V. (2000) Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes. J. Biol. Chem., 275, 15789-15798.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15789-15798
    • Kasparkova, J.1    Farrell, N.2    Brabec, V.3
  • 23
    • 0034034773 scopus 로고    scopus 로고
    • DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands
    • Malina, J., Hofr, C., Maresca, L., Natile, G. and Brabec, V. (2000) DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands. Biophys. J., 78, 2008-2021.
    • (2000) Biophys. J. , vol.78 , pp. 2008-2021
    • Malina, J.1    Hofr, C.2    Maresca, L.3    Natile, G.4    Brabec, V.5
  • 24
    • 0035971148 scopus 로고    scopus 로고
    • Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer
    • Hofr, C. and Brabec, V. (2001) Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer. J. Biol. Chem., 276, 9655-9661.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9655-9661
    • Hofr, C.1    Brabec, V.2
  • 25
    • 66749144729 scopus 로고    scopus 로고
    • Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+
    • Nová ková, O., Malina, J., Kas pá rková, J., Halá miková, A., Bernard, V., Intini, F., Natile, G. and Brabec, V. (2009) Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+. Chem. Eur. J., 15, 6211-6221.
    • (2009) Chem. Eur. J. , vol.15 , pp. 6211-6221
    • Nováková, O.1
  • 26
    • 0027301069 scopus 로고
    • DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues
    • Brabec, V. and Leng, M. (1993) DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues. Proc. Natl Acad. Sci. USA, 90, 5345-5349.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 5345-5349
    • Brabec, V.1    Leng, M.2
  • 27
    • 0029034092 scopus 로고
    • Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: Relation with the clinical inefficiency of transplatin
    • Boudvillain, M., Dalbies, R., Aussourd, C. and Leng, M. (1995) Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relation with the clinical inefficiency of transplatin. Nucleic Acids Res., 23, 2381-2388.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2381-2388
    • Boudvillain, M.1    Dalbies, R.2    Aussourd, C.3    Leng, M.4
  • 28
    • 0029821230 scopus 로고    scopus 로고
    • Influence of cisplatin intrastrand crosslinking on the conformation thermal stability, and energetics of a 20-mer DNA duplex
    • Poklar, N., Pilch, D.S., Lippard, S.J., Redding, E.A., Dunham, S.U. and Breslauer, K.J. (1996) Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc. Natl Acad. Sci. USA, 93, 7606-7611.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 7606-7611
    • Poklar, N.1    Pilch, D.S.2    Lippard, S.J.3    Redding, E.A.4    Dunham, S.U.5    Breslauer, K.J.6
  • 29
    • 0034711943 scopus 로고    scopus 로고
    • DNA sequence context modulates the impact of a cisplatin 1, 2-d(GpG) intrastrand cross-link an the conformational and thermodynamic properties of duplex DNA
    • Pilch, D.S., Dunham, S.U., Jamieson, E.R., Lippard, S.J. and Breslauer, K.J. (2000) DNA sequence context modulates the impact of a cisplatin 1, 2-d(GpG) intrastrand cross-link an the conformational and thermodynamic properties of duplex DNA. J. Mol. Biol., 296, 803-812.
    • (2000) J. Mol. Biol. , vol.296 , pp. 803-812
    • Pilch, D.S.1    Dunham, S.U.2    Jamieson, E.R.3    Lippard, S.J.4    Breslauer, K.J.5
  • 30
    • 0030452294 scopus 로고    scopus 로고
    • Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies
    • Kasparkova, J., Mellish, K.J., Qu, Y., Brabec, V. and Farrell, N. (1996) Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies. Biochemistry, 35, 16705-16713.
    • (1996) Biochemistry , vol.35 , pp. 16705-16713
    • Kasparkova, J.1    Mellish, K.J.2    Qu, Y.3    Brabec, V.4    Farrell, N.5
  • 31
    • 0023406843 scopus 로고
    • Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves
    • Marky, L.A. and Breslauer, K.J. (1987) Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves. Biopolymers, 26, 1601-1620.
    • (1987) Biopolymers , vol.26 , pp. 1601-1620
    • Marky, L.A.1    Breslauer, K.J.2


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