Thermophilic archaeal enzymes and applications in biocatalysis

Biochemical Society Transactions

Volumn 39, Issue 1, 2011, Pages 155-158

  Littlechild, Jennifer A ^a  

^a UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

Archaea; Biocatalysis; Immobilization; Thermophile

Indexed keywords

ALCOHOL DEHYDROGENASE; AMIDASE; AMINOTRANSFERASE; BACTERIAL ENZYME; PENICILLINASE;

AEROPYRUM PERNIX; BIOCATALYSIS; CONFERENCE PAPER; ENZYME ANALYSIS; ENZYME STABILITY; NONHUMAN; PRIORITY JOURNAL; SULFOLOBUS SOLFATARICUS; THERMOPHILIC ARCHAEON; THERMOSTABILITY;

AEROPYRUM; ALCOHOL DEHYDROGENASE; AMIDOHYDROLASES; AMINOHYDROLASES; ARCHAEA; ARCHAEAL PROTEINS; BIOCATALYSIS; GREEN CHEMISTRY TECHNOLOGY; HYDROLASES; MODELS, MOLECULAR; PROTEIN CONFORMATION; SULFOLOBUS SOLFATARICUS; THERMOCOCCUS; TRANSAMINASES;

AEROPYRUM PERNIX; ARCHAEA; BACTERIA (MICROORGANISMS); EUKARYOTA; SULFOLOBUS; SULFOLOBUS SOLFATARICUS; THERMOCOCCUS LITORALIS;

EID: 79551481359     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0390155     Document Type: Conference Paper

References (24)

1. Singleton, M.R., Taylor, S.J., Parrat, J.S. and Littlechild, J.A. (2000) Cloning, expression, and characterization of pyrrolidone carboxyl peptidase from the archaeon Thermococcus litoralis. Extremophiles 4, 297-303
2. Singleton, M.R., Isupov, M.N. and Littlechild, J.A. (1999) Crystallization and preliminary X-ray diffraction studies of pyrrolidone carboxyl peptidase from the hyperthermophilic archaeon Thermococcus litoralis. Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 702-703
3. Singleton, M.R., Isupov, M.N. and Littlechild, J.A. (1999) X-ray structure of pyrrolidone carboxyl peptidase from the hyperthermophilic archaeon Thermococcus litoralis. Structure 7, 237-244
4. Toogood, H.S., Hollingsworth, E.J., Brown, R.C., Taylor, I.N., Taylor, S.J.C., McCague, R. and Littlechild, J.A. (2002) A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations. Extremophiles 6, 111-122
5. Tanimoto, K., Higashi, N., Nishioka, M., Ishikawa, K. and Taya, M. (2008) Characterization of thermostable aminoacylase from hyperthermophilic archaeon Pyrococcus horikoshii. FEBS J. 275, 1140-1149
6. Colombo, S., Toietta, G., Zecca, L., Vanoni, M. and Tortora, P. (1995) Molecular cloning, nucleotide sequence and expression of a carboxypeptidase- encoding gene from the archaebacterium Sulfolobus solfataricus. J. Bacteriol. 177, 5561-5566
7. Toogood, H.S., Taylor, I.N., Brown, R.C., Taylor, S.J. C., McCague, R. and Littlechild, J.A. (2002) Immobilisation of the thermostable L-aminoacylase from Thermococcus litoralis to generate a reuseable industrial biocatalyst. Biocatal. Biotransform. 20, 241-249
8. Ngamsom, B., Hickey, A.M., Greenway, G.M., Littlechild, J.A., Watts, P. and Wiles, C. (2010) Development of a high throughput screening tool for biotransformations utilising a thermophilic L-aminoacylase enzyme. J. Mol. Catal. B 63, 81-86
9. Hollingsworth, E.J., Isupov, M.N. and Littlechild, J.A. (2002) Crystallization and preliminary X-ray diffraction analysis of L-aminoacylase from the hyperthermophilic archaeon Thermococcus litoralis. Acta Crystallogr. Sect. D Biol. Crystallogr. 58, 507-510
10. Toogood, H., Brown, R., Line, K., Keene, P., Taylor, S., McCague, R. and Littlechild, J.A. (2004) The use of a thermostable signature amidase in the resolution of the bicyclic synthon (rac)-γ-lactam. Tetrahedron 60, 711-716
11. Kobayashi, M., Fujiwara, Y., Goda, M., Komeda, H. and Shimizu, S. (1997) Identification of active sites in amidase: evolutionary relationship between amide bond- and peptide bond-cleaving enzymes. Proc. Natl. Acad. Sci. U.S.A. 94, 11986-11991
12. Waddell, S. (2006) Investigations into the archaeal C-N bond hydrolysing enzymes nitrilase and amidase. Ph.D. Thesis, University of Exeter, Exeter, U.K.
13. Hickey, A.M., Ngamsom, B., Wiles, C., Greenway, G.M., Watts, P. and Littlechild, J.A. (2009) A microreactor for the study of biotransformations by a cross-linked γ-lactamase enzyme. Biotechnol. J. 4, 510-516
14. Guy, J.E., Isupov, M.N. and Littlechild, J.A. (2003) Crystallization and preliminary X-ray diffraction studies of a novel alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. Acta Crystallogr. Sect. D Biol. Crystallogr. 59, 174-176
15. Guy, J.E., Isupov, M.N. and Littlechild, J.A. (2003) The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. J. Mol. Biol. 331, 1041-1051
16. Esposito, L, Sica, F., Raia, C.A., Giordano, A., Rossi, M., Mazzarella, L. and Zagari, A. (2002) Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 Å resolution. J. Mol. Biol. 318, 463-477
17. Mallick, P., Boutz, D.R., Eisenberg, D. and Yeates, T.O. (2002) Genomic evidence that the intracellular proteins of archaeal microbes contain disulfide bonds. Proc. Natl. Acad. Sci. U.S.A. 99, 9679-9684
18. Rye, C.A., Isupov, M.N., Lebedev, A.A. and Littlechild, J.A. (2007) An order-disorder twin crystal of L-2-haloacid dehalogenase from Sulfolobus tokodaii. Acta Crystallogr. Sect. D Biol. Crystallogr. 63, 926-930
19. Rye, C.A., Isupov, M.N., Lebedev, A.A. and Littlechild, J.A. (2009) Biochemical and structural studies of an L-haloacid dehalogenase from the thermophilic archaeon Sulfolobus tokodaii. Extremophiles 13, 179-190
20. Arai, R., Kukimoto-Niino, M., Sugahara, M., Shirouzu, M. and Yokoyama, S. (2006) Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3. Protein Sci. 15, 373-377
21. Bommer, M.J.S. (2008) Accelerating the discovery of transaminase biocatalysts. Ph.D. Thesis, University College London, London, U.K.
22. Chen, B.H., Sayar, A., Kaulmann, U., Dalby, P.A., Ward, J.M. and Woodley, J.M. (2007) Reaction modelling and simulation to assess the integrated use of transketolase and ω-transaminase for the synthesis of an aminotriol. Biocatal. Biotransform. 24, 449-457
23. Sayer, C. (2009) Structural Studies on ω-Amine:Pyruvate and Serine:Pyruvate Aminotransferase Enzymes. Ph.D. Thesis, University of Exeter, Exeter, U.K.
24. Meyer, P., Liger, D., Leulliot, N., Quevillon-Cheruel, S., Zhou, C.-Z., Borel, F., Ferrer, J.-L., Poupon, A., Janin, J. and van Tilbeurgh, H. (2005) Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein. Biochimie 87, 1041-1047 (Pubitemid 41572633)