Enantiospecific (+)- and (-)-germacrene D synthases, cloned from goldenrod, reveal a functionally active variant of the universal isoprenoid-biosynthesis aspartate-rich motif

Archives of Biochemistry and Biophysics

Volumn 432, Issue 2, 2004, Pages 136-144

  Prosser, Ian ^a   Altug, Iris G ^b,c   Phillips, Andy L ^a   König, Wilfried A ^b   Bouwmeester, Harro J ^c   Beale, Michael H ^a,d  

^a ROTHAMSTED RESEARCH   (United Kingdom)

^b UNIVERSITY OF HAMBURG   (Germany)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Enantiomers; Enantiospecificity; Germacrene D; Sesquiterpene; Solidago; Terpene cyclase

Indexed keywords

ASPARTIC ACID; COMPLEMENTARY DNA; ENZYME; GERMACRENE DEXTRO SYNTHASE; ISOPRENOID; MAGNESIUM; SESQUITERPENE; SOLIDAGO CANADENSIS EXTRACT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME STRUCTURE; GENETIC VARIABILITY; MOLECULAR CLONING; MOLECULAR MODEL; MUTAGENICITY; NUCLEOTIDE SEQUENCE; PLANT GENETICS; PLANT INSECT INTERACTION; PRIORITY JOURNAL; PROTEIN MOTIF; SOLIDAGO;

ALKYL AND ARYL TRANSFERASES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ASPARTIC ACID; BINDING SITES; CELLS, CULTURED; CLONING, MOLECULAR; COMPUTER SIMULATION; ENZYME ACTIVATION; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SOLIDAGO; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TERPENES;

ESCHERICHIA COLI; INSECTA; SOLIDAGO; SOLIDAGO CANADENSIS;

EID: 7944232372     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2004.06.030     Document Type: Article

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