An assessment of the risks of carcinogenicity associated with polyhydroxyalkanoates through an analysis of DNA aneuploid and telomerase activity

Biomaterials

Volumn 32, Issue 10, 2011, Pages 2546-2555

  Peng, Si Wu ^a   Guo, Xiao Yong ^a   Shang, Guan Guan ^a   Li, Jian ^a   Xu, Xian Yi ^a   You, Ming Liang ^a   Li, Ping ^a   Chen, Guo Qiang ^b  

^a SHANTOU UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Carcinogenesis; PHB; PHBHHx; Polyhydroxyalkanoates; Proliferation; Telomerase

Indexed keywords

CARCINOGENESIS; PHB; PHBHHX; POLYHYDROXYALKANOATES; PROLIFERATION; TELOMERASE;

BIOCOMPATIBILITY; BIODEGRADATION; BIOLOGICAL MATERIALS; CELL PROLIFERATION; DRUG DELIVERY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GROWTH KINETICS; MECHANICAL PROPERTIES; PATHOLOGY; POLYMERASE CHAIN REACTION; TUMORS;

CELL GROWTH;

DNA; GENOMIC DNA; KI 67 ANTIGEN; POLYHYDROXYALKANOIC ACID; PROTEIN C FOS; PROTEIN P53; TELOMERASE;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CARCINOGENICITY; CELL CYCLE REGULATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC RISK; GENETIC SUSCEPTIBILITY; MITOSIS; NONHUMAN; ONCOGENE C FOS; OSTEOBLAST; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; TELOMERE;

ANEUPLOIDY; ANIMALS; BROMODEOXYURIDINE; CARCINOGENICITY TESTS; CELL PROLIFERATION; DNA; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; POLYHYDROXYALKANOATES; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RNA, MESSENGER; TELOMERASE; TELOMERE;

RATTUS;

EID: 79251596685     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.12.051     Document Type: Article

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