The effect of 3-hydroxybutyrate on the in vitro differentiation of murine osteoblast MC3T3-E1 and in vivo bone formation in ovariectomized rats

Biomaterials

Volumn 28, Issue 20, 2007, Pages 3063-3073

  Zhao, Yan ^a   Zou, Bing ^a   Shi, Zhenyu ^a   Wu, Qiong ^a   Chen, Guo Qiang ^a,b  

^a YANGTZE RIVER SCIENTIFIC RESEARCH INSTITUTE   (China)

^b SHANTOU UNIVERSITY   (China)

Author keywords

3 hydroxybutyrate; Osteoblast; Osteoporosis; PHA; Polyhydroxyalkanoate

Indexed keywords

ASSAYS; BIODIVERSITY; BONE; ENZYMES; GROWTH KINETICS; OSTEOBLASTS;

3-HYDROXYBUTYRATE; BONE FORMATION; OSTEOPOROSIS; POLYHYDROXYALKANOATE;

BIOMATERIALS;

3 HYDROXYBUTYRIC ACID; ALIZARIN RED S; ALKALINE PHOSPHATASE; MESSENGER RNA; OSTEOCALCIN; POLYHYDROXYALKANOIC ACID;

ANIMAL CELL; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE GROWTH; BONE STRUCTURE; CELL DIFFERENTIATION; CELL GROWTH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FEMUR; IMPLANT; IN VITRO STUDY; IN VIVO STUDY; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STAINING; TRABECULAR BONE;

3T3 CELLS; ALKALINE PHOSPHATASE; ANIMALS; BONE DENSITY; CALCIUM; CELL DIFFERENTIATION; FEMALE; FEMUR; HYDROXYBUTYRATES; MICE; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OVARIECTOMY; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIBIA;

ANIMALIA; MURINAE; RATTUS; RATTUS NORVEGICUS;

EID: 34247148505     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.03.003     Document Type: Article

References (49)

1. Wang Y.W., Wu Q., and Chen G.Q. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds with good biocompatibility for osteoblast proliferation and differentiation. Biomaterials 25 (2004) 669-675
2. Wang Y.W., Wu Q., Chen J.C., and Chen G.Q. Evaluation of hydroxyapatite (HAP) incorporation into 3-dimensional scaffold made of poly(3-hydroxybutyrate-co-3- hydroxyhexanoate) (PHBHHx) for bone reconstruction. Biomaterials 26 (2004) 899-904
3. Wang Y.W., Yang F., Cheng Y.C., Yu P.H.F., Chen J.C., Wu Q., et al. Effect of composition of poly (3-hydroxybutyrate-co-3-hydroxylhexanoate) on growth of fibroblast and osteoblast. Biomaterials 26 (2005) 755-761
4. Deng Y., Zhao K., Zhang X.F., Hu P., and Chen G.Q. Study on the three-dimensional proliferation of rabbit articular cartilage derived chondrocytes on polyhydroxyalkanoate scaffolds. Biomaterials 23 (2002) 4049-4056
5. Robinson A., and Williamson D. Physiological roles of ketone bodies as substrates and signals in mammalian tissues. Physiol Rev 60 (1980) 143-187
6. Curi R., Lagranha C.J., Doi S.Q., et al. Molecular mechanisms of glutamine action. J Cell Physiol 204 2 (2005) 392-401
7. Katayama M., Hiraide A., Sugimoto H., Yoshioka T., and Sugimoto T. Effect of ketone bodies on hyperglycemia and lactic acidemia in hemorrhagic stress. J Parenter Enteral Nutr 18 (1994) 444-446
8. Lin T., Koustova E., Chen H.Z., Rhee P.M., Kirkpatrick J., and Alam H.B. Energy substrate-supplemented resuscitation affects brain monocarboxylate transporter levels and gliosis in a rat model of hemorrhagic shock. J Trauma 59 (2005) 1191-1202
9. Mizobata Y., Hiraide A., Katayama M., Sugimoto H., Yoshioka T., and Sugimoto T. Oxidation of d(-)3-hydroxybutyrate administered to rats with extensive burns. Surg Today 26 (1996) 173-178
10. Zou Z., Sasaguri S., Rajesh K.G., and Suzuki R. dl-3-hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts. Am J Physiol-Heart C Physiol 283 5 (2002) H1968-H1974
11. Suzuki M., Sato K., Dohi S., Sato T., Matsuura A., and Hiraide A. Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats. Jpn J Pharmacol 87 (2001) 143-150
12. Kashiwaya Y., Takeshima T., Mori N., Nakashima K., Clarke K., and Veech R.L. d-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc Nat Acad Sci USA 97 (2000) 5440-5444
13. Nakamura S., Shibuya M., Saito Y., Nakashima H., Saito F., Higuchi A., et al. Protective effect of d-beta-hydroxybutyrate on corneal epithelia in dry eye conditions through suppression of apoptosis. Invest Ophthalmol Vis Sci 44 (2003) 4682-4688
14. Tieu K., Perier C., Caspersen C., Teismann P., Wu D.C., Yan S.D., et al. d-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease. J Clin Invest 112 (2003) 892-901
15. Plecko B., Stoeckler-Ipsiroglu S., Schober E., Harrer G., Mlynarik V., Gruber S., et al. Oral beta-hydroxybutyrate supplementation in two patients with hyperinsulinemic hypoglycemia: monitoring of beta-hydroxybutyrate levels in blood and cerebrospinal fluid, and in the brain by in vivo magnetic resonance spectroscopy. Pediatr Res 52 (2002) 301-306
16. Veech R.L., Chance B., Kashiwaya Y., Lardy H.A., and Cahill Jr. G.F. Ketone bodies, potential therapeutic uses. IUBMB Life 51 (2001) 241-247
17. Zhao K., Deng Y., Chen J.C., and Chen G.Q. Polyhydroxyalkanoate (PHA) scaffolds with good mechanical properties and biocompatibility. Biomaterials 24 (2003) 1041-1045
18. Chen G.Q., and Wu Q. The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 (2005) 6565-6578
19. Qu X.H., Wu Q., Zhang K.Y., and Chen G.Q. In vivo studies of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) based polymers: biodegradation and tissue reactions. Biomaterials 27 (2006) 3540-3548
20. Wang Y.W., Wu Q., and Chen G.Q. Increased hydrophilicity of microbial polyhydroxyalkanoates via hyaluronan coating reduced growth of mouse fibroblast L929 cells. Biomaterials 25 (2003) 4621-4629
21. Deng Y., Lin X.S., Zheng Z., Deng J.G., Chen J.C., Ma H., et al. Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro. Biomaterials 24 (2003) 4473-4481
22. Yang X.S., Zhao K., and Chen G.Q. Effect of surface treatment on the biocompatibility of microbial polyhydroxyalkanoates. Biomaterials 23 (2002) 1391-1397
23. Zhao K., Deng Y., Chen J.C., and Chen G.Q. Polyhydroxyalkanoate (PHA) scaffolds with good mechanical properties and biocompatibility. Biomaterials 24 (2003) 1041-1054
24. Yang M., Zhu S.S., Chen Y., Chang Z.J., Chen G.Q., Gong Y.D., et al. Studies on bone marrow stromal cells affinity of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). Biomaterials 25 (2004) 1365-1373
25. Kang I.K., Choi S.H., Shin D.S., and Yoon S.C. Surface modification of polyhydroxyalkanoate films and their interaction with human fibroblasts. Int J Biol Macromol 28 3 (2001) 205-212
26. Cheng S., Wu Q., Yang F., Xu M., Leski M., and Chen G.Q. Influence of dl-beta-hydroxybutyric acid on cell proliferation and calcium influx. Biomacromolecules 6 (2005) 593-597
27. Cheng S., Chen G.Q., Leski M., Zou B., Wang Y., and Wu Q. The effect of d, l-ß-hydroxybutyric acid on cell death and proliferation in L929 cells. Biomaterials 27 (2006) 3758-3765
28. Shaarawy M., and Hasan M. Serum bone sialoprotein: a marker of bone resorption in postmenopausal osteoporosis. Scand J Clin Lab Inv 61 7 (2001) 513-521
29. Morley P., Whitfield J.F., and Willick G.E. Parathyroid hormone: an anabolic treatment for osteoporosis. Curr Pharm Design 7 8 (2001) 671-687
30. Lee TC, McHugh PE, O'Brien FJ, O'Mahoney D, Taylor D, Bruzzi M, et al. Bone for life: osteoporosis, bone remodeling and computer simulation. In: Prendergast PJ, McHugh PE, editors. Topics in bio-mechanical engineering. Galway, Ireland, 2004. p. 58-93.
31. Canalis E. Novel treatments for osteoporosis. J Clin Invest 106 (2000) 177-179
32. Delmas P.D. Treatment of postmenopausal osteoporosis. Lancet 359 (2002) 2018-2026
33. Schiller P.C., D'Ippolito G., Roos B.A., and Howard G.A. Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment. J Bone Miner Res 14 (1999) 1504-1512
34. Corral D.A., Amling M., Priemel M., Loyer E., Fuchs S., Ducy P., et al. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proc Nat Acad Sci USA 95 (1998) 13835-13840
35. Kazuo I., and Toshie T. Enhancing effect of poly(l-lactide) on the differentiation of mouse osteoblast-like MC3T3-E1 cells. Biomaterials 24 (2003) 3303-3309
36. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
37. Harnano T., Chiba D., Nakatsuka K., Nagahata M., Teramoto A., Kondo Y., et al. Evaluation of a polyelectrolyte complex (PEC) composed of chitin derivatives and chitosan, which promotes the rat calvarial osteoblast differentiation. Polym Adv Technol 13 (2002) 46-53
38. Chen V.J., Smith L.A., and Ma P.X. Bone regeneration on computer-designed nano-fibrous scaffolds. Biomaterials 27 (2006) 3973-3979
39. Feige J.N., Sage D., Wahli W., et al. PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs. Microsc Res Techn 68 1 (2005) 51-58
40. National Research Council. Guide for the care and the use of laboratory animals (1996), National Academy Press, Washington DC
41. Iwasaki-Ishizuka Y., Yamato H., Murayama H., Ezawa I., Kurokawa K., and Fukagawa M. Menatetrenone rescues bone loss by improving osteoblast dysfunction in rats immobilized by sciatic neurectomy. Life Sci 76 (2005) 1721-1734
42. Xie F., Wu C.F., Lai W.P., Yang X.J., Cheung P.Y., Yao X.S., et al. The osteoprotective effect of Herba epimedii (HEP) extract in vivo and in vitro. Evid Based Complement Alternat Med 2 3 (2005) 353-361
43. Van Soesbergen R.M., Lips P., et al. Bone metabolism in rheumatoid arthritis compared with postmenopausal osteoporosis. Ann Rheum Dis 45 (1986) 149
44. Engelmayr G.C., Hildebrand D.K., Sutherland F.W.H., Mayer J.E., and Sacks M.S. A novel bioreactor for the dynamic flexural stimulation of tissue engineered heart valve biomaterials. Biomaterials 24 (2003) 2523-2532
45. Tomkinson A., Gevers E.F., Wit J.M., Reeve J., and Noble B.S. The role of estrogen in the control of rat osteocyte apoptosis. J Bone Miner Res 13 (1998) 1243-1250
46. Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest 115 (2005) 3318-3325
47. Shangguan Y.Y., Wang Y.W., Wu Q., and Chen G.Q. The mechanical properties and in vitro biodegradation and biocompatibility of UV-treated poly (3-hydroxybutyrate-co-3-hydroxyhexanoate). Biomaterials 27 (2006) 2349-2357
48. Lynch M.P., Capparelli C., Stein J.L., Stein G.S., and Lian J.B. Apoptosis during bone-like tissue development in vitro. J Cell Biochem 68 (1998) 31-49
49. Hock J.M., Krishnan V., Onyia J.E., Bidwell J.P., Milas J., and Stanislaus D. Osteoblast apoptosis and bone turnover. J Bone Miner Res 16 (2001) 975-984