Biophysical mechanisms underlying olfactory receptor neuron dynamics

Nature Neuroscience

Volumn 14, Issue 2, 2011, Pages 208-218

  Nagel, Katherine I ^a   Wilson, Rachel I ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL;

ADAPTATION; CONFERENCE PAPER; CONTROLLED STUDY; DROSOPHILA; FEEDBACK SYSTEM; FEMALE; FILTER; GENETIC MANIPULATION; NONHUMAN; ODOR; OLFACTORY RECEPTOR; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPIKE WAVE; STEREOTYPY; VELOCITY;

ANIMALS; DROSOPHILA; ELECTROPHYSIOLOGY; ODORS; OLFACTORY RECEPTOR NEURONS; SIGNAL TRANSDUCTION; SMELL;

EID: 79251594106     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn.2725     Document Type: Conference Paper

References (50)

1. Murlis, J., Elkinton, J.S. & Cardé, R.T. Odor plumes and how insects use them. Annu. Rev. Entomol. 37, 505-532 (1992).
2. Vickers, N.J., Christensen, T.A., Baker, T.C. & Hildebrand, J.G. Odour-plume dynamics infuence the brain's olfactory code. Nature 410, 466-470 (2001).
3. Kang, J. & Caprio, J. Electrophysiological responses of single olfactory bulb neurons to binary mixtures of amino acids in the channel catfsh, Ictalurus punctatus. J. Neurophysiol. 74, 1435-1443 (1995).
4. De Bruyne, M., Clyne, P.J. & Carlson, J.R. Odor coding in a model olfactory organ: the Drosophila maxillary palp. J. Neurosci. 19, 4520-4532 (1999).
5. Reisert, J. & Matthews, H.R. Adaptation of the odour-induced response in frog olfactory receptor cells. J. Physiol. (Lond.) 519, 801-813 (1999).
6. De Bruyne, M., Foster, K. & Carlson, J.R. Odor coding in the Drosophila antenna. Neuron 30, 537-552 (2001).
7. 2+ channel in Drosophila. J. Neurosci. 19, 4839-4846 (1999).
8. Gu, Y., Lucas, P. & Rospars, J.P. Computational model of the insect pheromone transduction cascade. PLOS Comput. Biol. 5, e1000321 (2009).
9. Flecke, C. & Stengl, M. Octopamine and tyramine modulate pheromone-sensitive olfactory sensilla of the hawkmoth Manduca sexta in a time-dependent manner. J. Comp. Physiol. A Neuroethol. Sens. Neural Behav. Physiol. 195, 529-545 (2009).
10. Kaissling, K.E. Flux detectors versus concentration detectors: two types of chemoreceptors. Chem. Senses 23, 99-111 (1998).
11. Hallem, E.A., Ho, M.G. & Carlson, J.R. The molecular basis of odor coding in the Drosophila antenna. Cell 117, 965-979 (2004).
12. Sato, K. et al. Insect olfactory receptors are heteromeric ligand-gated ion channels. Nature 452, 1002-1006 (2008).
13. Benton, R., Sachse, S., Michnick, S.W. & Vosshall, L.B. Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol. 4, e20 (2006).
14. 2-sensing neurons in Drosophila. J. Neurosci. 30, 4562-4572 (2010).
15. Wicher, D. et al. Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels. Nature 452, 1007-1011 (2008).
16. Schuckel, J., Torkkeli, P.H. & French, A.S. Two interacting olfactory transduction mechanisms have linked polarities and dynamics in Drosophila melanogaster antennal basiconic sensilla neurons. J. Neurophysiol. 102, 214-223 (2009).
17. Dobritsa, A.A., Van der Goes Van Naters, W., Warr, C.G., Steinbrecht, R.A. & Carlson, J.R. Integrating the molecular and cellular basis of odor coding in the Drosophila antenna. Neuron 37, 827-841 (2003).
18. Goldman, A.L., Van der Goes Van Naters, W., Lessing, D., Warr, C.G. & Carlson, J.R. Coexpression of two functional odor receptors in one neuron. Neuron 45, 661-666 (2005).
19. Johnston, D. & Wu, S.M.-S. Foundations of Cellular Neurophysiology (MIT Press, 1995).
20. Kaissling, K.E. Chemo-electrical transduction in insect olfactory receptors. Annu. Rev. Neurosci. 9, 121-145 (1986).
21. Schneider, D. Insect olfaction: deciphering system for chemical messages. Science 163, 1031-1037 (1969).
22. Baccus, S.A. & Meister, M. Fast and slow contrast adaptation in retinal circuitry. Neuron 36, 909-919 (2002).
23. Nagel, K.I. & Doupe, A.J. Temporal processing and adaptation in the songbird auditory forebrain. Neuron 51, 845-859 (2006).
24. Kim, A.J., Lazar, A.A. & Slutskiy, Y.B. System identifcation of Drosophila olfactory sensory neurons. J. Comput. Neurosci. published online doi:10.1007/s10827-010-0265-0 (21 August 2010).
25. Lundstrom, B.N., Hong, S., Higgs, M.H. & Fairhall, A.L. Two computational regimes of a single-compartment neuron separated by a planar boundary in conductance space. Neural Comput. 20, 1239-1260 (2008).
26. Hallem, E.A. & Carlson, J.R. Coding of odors by a receptor repertoire. Cell 125, 143-160 (2006).
27. Geffen, M.N., Broome, B.M., Laurent, G. & Meister, M. Neural encoding of rapidly fuctuating odors. Neuron 61, 570-586 (2009).
28. Rushton, W.A. Pigments and signals in colour vision. J. Physiol. 220, 1P-P (1972).
29. Laurent, G., Wehr, M. & Davidowitz, H. Temporal representations of odors in an olfactory network. J. Neurosci. 16, 3837-3847 (1996).
30. Daly, K.C., Wright, G.A. & Smith, B.H. Molecular features of odorants systematically infuence slow temporal responses across clusters of coordinated antennal lobe units in the moth Manduca sexta. J. Neurophysiol. 92, 236-254 (2004).
31. Stopfer, M., Jayaraman, V. & Laurent, G. Intensity versus identity coding in an olfactory system. Neuron 39, 991-1004 (2003).
32. Raman, B., Joseph, J., Tang, J. & Stopfer, M. Temporally diverse fring patterns in olfactory receptor neurons underlie spatiotemporal neural codes for odors. J. Neurosci. 30, 1994-2006 (2010).
33. Soo, F.S., Detwiler, P.B. & Rieke, F. Light adaptation in salamander L-cone photoreceptors. J. Neurosci. 28, 1331-1342 (2008).
34. Deshpande, M., Venkatesh, K., Rodrigues, V. & Hasan, G. The inositol 1,4,5-trisphosphate receptor is required for maintenance of olfactory adaptation in Drosophila antennae. J. Neurobiol. 43, 282-288 (2000).
35. Neuhaus, E.M. et al. Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster. Nat. Neurosci. 8, 15-17 (2005).
36. Liu, M., Chen, T.Y., Ahamed, B., Li, J. & Yau, K.W. Calcium-calmodulin modulation of the olfactory cyclic nucleotide-gated cation channel. Science 266, 1348-1354 (1994).
37. Kaissling, K.E., Zack Strausfeld, C. & Rumbo, E. Adaptation processes in insect olfactory receptors. Mechanisms and behavioral signifcance. Ann. NY Acad. Sci. 510, 104-112 (1987).
38. Reyes, A.D., Rubel, E.W. & Spain, W.J. Membrane properties underlying the fring of neurons in the avian cochlear nucleus. J. Neurosci. 14, 5352-5364 (1994).
39. Rauch, A., La Camera, G., Luscher, H.R., Senn, W. & Fusi, S. Neocortical pyramidal cells respond as integrate-and-fre neurons to in vivo-like input currents. J. Neurophysiol. 90, 1598-1612 (2003).
40. Famulare, M. & Fairhall, A. Feature selection in simple neurons: how coding depends on spiking dynamics. Neural Comput. 22, 581-598 (2010).
41. Bhandawat, V., Olsen, S.R., Schlief, M.L., Gouwens, N.W. & Wilson, R.I. Sensory processing in the Drosophila antennal lobe increases the reliability and separability of ensemble odor representations. Nat. Neurosci. 10, 1474-1482 (2007).
42. Field, G.D., Sampath, A.P. & Rieke, F. Retinal processing near absolute threshold: from behavior to mechanism. Annu. Rev. Physiol. 67, 491-514 (2005).
43. Spors, H., Wachowiak, M., Cohen, L.B. & Friedrich, R.W. Temporal dynamics and latency patterns of receptor neuron input to the olfactory bulb. J. Neurosci. 26, 1247-1259 (2006).
44. Carey, R.M., Verhagen, J.V., Wesson, D.W., Pirez, N. & Wachowiak, M. Temporal structure of receptor neuron input to the olfactory bulb imaged in behaving rats. J. Neurophysiol. 101, 1073-1088 (2009).
45. Bhandawat, V., Reisert, J. & Yau, K.W. Elementary response of olfactory receptor neurons to odorants. Science 308, 1931-1934 (2005).
46. Almaas, T.J., Christensen, T.A. & Mustaparta, H. Chemical communication in heliothine moths. 1. Antennal receptor neurons encode several features of intraspecifc and interspecifc odorants in the male corn-earworm moth Helicoverpa zea. J. Comp. Physiol. A Neuroethol. Sens. Neural Behav. Physiol. 169, 249-258 (1991).
47. Olsen, S.R., Bhandawat, V. & Wilson, R.I. Excitatory interactions between olfactory processing channels in the Drosophila antennal lobe. Neuron 54, 89-103 (2007).
48. Sweeney, L.B. et al. Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions. Neuron 53, 185-200 (2007).
49. Couto, A., Alenius, M. & Dickson, B.J. Molecular, anatomical, and functional organization of the Drosophila olfactory system. Curr. Biol. 15, 1535-1547 (2005).
50. Budick, S.A. & Dickinson, M.H. Free-fight responses of Drosophila melanogaster to attractive odors. J. Exp. Biol. 209, 3001-3017 (2006).