Development and in-house validation of allergen-specific ELISA tests for the quantification of Dau c 1.01, Dau c 1.02 and Dau c 4 in carrot extracts (Daucus carota)

Analytical and Bioanalytical Chemistry

Volumn 399, Issue 2, 2011, Pages 935-943

  Foetisch, Kay ^a   Dahl, Lotte ^a   Jansen, Baerbel ^b   Becker, Wolf Meinhard ^c   Lidholm, Jonas ^d   Van Ree, Ronald ^e   Broll, Hermann ^b   Kaul, Susanne ^a   Vieths, Stefan ^a   Holzhauser, Thomas ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

^b Division of Food Safety   (Germany)

^c RESEARCH CENTER BORSTEL   (Germany)

^d Thermo Fisher Scientific   (United States)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Allergen; Dau c 1.01; Dau c 1.02; Dau c 4; Daucus carota; ELISA

Indexed keywords

ALLERGEN; DAU C 1.01; DAU C 1.02; DAU C 4; DAUCUS CAROTA; ELISA;

ANTIGENS; MONOCLONAL ANTIBODIES;

ALLERGIES;

ALLERGEN; ISOPROTEIN; MONOCLONAL ANTIBODY; PLANT EXTRACT; VEGETABLE PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CARROT; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOLOGY; LIMIT OF DETECTION; METHODOLOGY; MOUSE; VALIDATION STUDY;

ALLERGENS; ANIMALS; ANTIBODIES, MONOCLONAL; DAUCUS CAROTA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; LIMIT OF DETECTION; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; PLANT PROTEINS; PROTEIN ISOFORMS;

APIUM GRAVEOLENS VAR. DULCE; DAUCUS CAROTA; ORYCTOLAGUS CUNICULUS;

EID: 79251561887     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4348-6     Document Type: Article

References (31)

1. S Vieths S Scheurer BK Ballmer-Weber 2002 Current understanding of cross-reactivity of food allergens and pollen Ann NY Acad Sci 964 47 68 1:CAS:528:DC%2BD38XltFalu7w%3D 10.1111/j.1749-6632.2002.tb04132.x
2. Zuberbier T, Edenharter G, Worm M, Ehlers I, Reimann S, Hantke T, Roehr CC, Bergmann KE, Niggemann B (2004) Prevalence of adverse reactions to food in Germany-a population study. 59(3):338-345
3. F André C André L Colin F Cacaraci S Cavagna 1994 Role of new allergens and of allergens consumption in the increased incidence of food sensitizations in France Toxicology 93 1 77 83 10.1016/0300-483X(94)90198-8
4. B Wüthrich 1993 Zur Nahrungsmittelallergie. Häufigkeit der Symptome und der allergieauslösenden Nahrungsmittel bei 402 Patienten - Kuhmilchallergie - Nahrungsmittel und Neurodermitis atopica. (Food allergy. Frequency of symptoms and allergenic foods in 402 patients-lactose intolerance, food and atopic dermatitis) Allergologie 16 7 280 287
5. M Etesamifar B Wüthrich 1998 IgE-vermittelte Nahrungsmittelallergien bei 383 Patienten unter Berücksichtigung des oralen Allergie-Syndroms Allergologie 21 9 451 457
6. BK Ballmer-Weber B Wüthrich A Wangorsch K Foetisch F Altmann S Vieths 2001 Carrot allergy: double-blinded, placebo-controlled food challenge and identification of allergens J Allergy Clin Immunol 108 2 Pt 1 301 307 1:CAS:528:DC%2BD3MXmslWqtro%3D 10.1067/mai.2001.116430
7. Fernandez-Rivas M, Gonzalez-Mancebo E, van Leeuwen WA, Leon F, van Ree R (2004) Anaphylaxis to raw carrot not linked to pollen allergy. 59(11):1239-1240
8. Gomez M, Curiel G, Mendez J, Rodriguez M, Moneo I (1996) Hypersensitivity to carrot associated with specific IgE to grass and tree pollens. 51(6):425-429
9. A Helbling M Lopez HJ Schwartz SB Lehrer 1993 Reactivity of carrot-specific IgE antibodies with celery, apiaceous spices, and birch pollen Ann Allergy 70 6 495 499 1:STN:280:DyaK3s3ot1KhsQ%3D%3D
10. I Moneo M Gomez R Sánchez-Monge E Alday M de las Heras I Esteban A Bootello G Salcedo 1999 Lack of crossreaction with Bet v 1 in patients sensitized to Dau c 1, a carrot allergen Ann Allergy Asthma Immunol 83 1 71 75 1:STN:280:DyaK1MzmsVGgsw%3D%3D 10.1016/S1081-1206(10)63516-8
11. A Moreno-Ancillo AC Gil-Adrados C Dominguez-Noche PM Cosmes F Pineda 2005 Occupational asthma due to carrot in a cook Allergol Immunopathol (Madr) 33 5 288 290 1:STN:280:DC%2BD2MnhtVemtg%3D%3D 10.1157/13080934
12. A Moreno-Ancillo AC Gil-Adrados PM Cosmes C Dominguez-Noche F Pineda 2006 Role of Dau c 1 in three different patterns of carrot-induced asthma Allergol Immunopathol (Madr) 34 3 116 120 10.1157/13088181
13. M Schiappoli G Senna A Dama P Bonadonna M Crivellaro G Passalacqua 2002 Anaphylaxis due to carrot as hidden food allergen Allergol Immunopathol (Madr) 30 4 243 244 1:STN:280:DC%2BD38vkt1alsA%3D%3D
14. HJ Schwartz JL Arnold KP Strohl 1995 Nasal response to carrot and lettuce challenge in allergic patients Ann Allergy Asthma Immunol 74 2 152 154 1:STN:280:DyaK2M3htFGktA%3D%3D
15. K Hoffmann-Sommergruber G O'Riordain H Ahorn C Ebner L da Camara M Machado HM Pühringer O Scheiner H Breiteneder 1999 Molecular characterization of Dau c 1, the Bet v 1 homologous protein from carrot and its cross-reactivity with Bet v 1 and Api g 1 Clin Exp Allergy 29 6 840 847 1:CAS:528:DyaK1MXktVymsr0%3D 10.1046/j.1365-2222.1999.00529.x
16. R Valenta M Duchêne C Ebner P Valent C Sillaber P Deviller F Ferreira M Tejkl H Edelmann D Kraft 1992 Profilins constitute a novel family of functional plant pan-allergens J Exp Med 175 2 377 385 1:CAS:528: DyaK38XotF2lug%3D%3D 10.1084/jem.175.2.377
17. Akkerdaas JH, van Ree R, Aalbers M, Stapel SO, Aalberse RC (1995) Multiplicity of cross-reactive epitopes on Bet v I as detected with monoclonal antibodies and human IgE. Allergy 50(3):215-220
18. JA Asturias MC Arilla M Aguirre N Gómez-Bayón A Martínez R Palacios F Sánchez-Gascón J Martínez 1999 Quantification of profilins by a monoclonal antibody-based sandwich ELISA J Immunol Methods 229 1-2 61 71 1:CAS:528:DyaK1MXnvFWksLc%3D 10.1016/S0022- 1759(99)00115-5
19. OA Duffort F Polo M Lombardero A Diaz-Perales R Sánchez-Monge G Garcia-Casado G Salcedo D Barber 2002 Immunoassay to quantify the major peach allergen Pru p 3 in foodstuffs. Differential allergen release and stability under physiological conditions J Agric Food Chem 50 26 7738 7741 1:CAS:528:DC%2BD38Xos1KjtLo%3D 10.1021/jf0258398
20. MT Werner CK Faeste E Egaas 2007 Quantitative sandwich ELISA for the determination of tropomyosin from crustaceans in foods J Agric Food Chem 55 20 8025 8032 1:CAS:528:DC%2BD2sXpt1Kqurw%3D 10.1021/jf070806j
21. BK Ballmer-Weber A Wangorsch B Bohle S Kaul T Kundig K Fotisch R van Ree S Vieths 2005 Component-resolved in vitro diagnosis in carrot allergy: does the use of recombinant carrot allergens improve the reliability of the diagnostic procedure? Clin Exp Allergy 35 7 970 978 1:CAS:528:DC%2BD2MXpsVWltLs%3D 10.1111/j.1365-2222.2005.02294.x
22. A Wangorsch BK Ballmer-Weber P Rosch T Holzhauser S Vieths 2007 Mutational epitope analysis and cross-reactivity of two isoforms of Api g 1, the major celery allergen Mol Immunol 44 10 2518 2527 1:CAS:528: DC%2BD2sXhvVSmurg%3D 10.1016/j.molimm.2006.12.023
23. G Reese BK Ballmer-Weber A Wangorsch S Randow S Vieths 2007 Allergenicity and antigenicity of wild-type and mutant, monomeric, and dimeric carrot major allergen Dau c 1: destruction of conformation, not oligomerization, is the roadmap to save allergen vaccines J Allergy Clin Immunol 119 4 944 951 1:CAS:528:DC%2BD2sXjvFaksbw%3D 10.1016/j.jaci.2006.11.699
24. Peters JH, Baumgarten H (1990) Monoklonale Antikörper - Herstellung und Charakterisierung. Springer, Berlin
25. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 1:CAS:528:DyaE28XksVehtrY%3D 10.1016/0003-2697(76)90527- 3
26. IB Wilson R Zeleny D Kolarich E Staudacher CJ Stroop JP Kamerling F Altmann 2001 Analysis of Asn-linked glycans from vegetable foodstuffs: widespread occurrence of Lewis a, core alpha1, 3-linked fucose and xylose substitutions Glycobiology 11 4 261 274 1:CAS:528:DC%2BD3MXjvFGksr4%3D 10.1093/glycob/11.4.261
27. IBH Wilson JE Harthill NP Mullin DA Ashford F Altmann 1998 Core alpha1, 3-fucose is a key part of the epitope recognized by antibodies reacting against plant N-linked oligosaccharides and is present in a wide variety of plant extracts Glycobiology 8 7 651 661 1:CAS:528:DyaK1cXksFClurg%3D 10.1093/glycob/8.7.651
28. UK Laemmli 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 5259 680 685 1:CAS:528: DC%2BD3MXlsFags7s%3D 10.1038/227680a0
29. J Kyhse-Andersen 1984 Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose J Biochem Biophys Methods 10 3-4 203 209 1:CAS:528: DyaL2MXhs1eisrc%3D 10.1016/0165-022X(84)90040-X
30. H Lowenstein SH Sparholt SS Klysner H Ipsen JN Larsen 1995 The significance of isoallergenic variations in present and future specific immunotherapy Int Arch Allergy Immunol 107 1-3 285 289 1:STN:280: DyaK2MzjslOmtQ%3D%3D
31. DY Son B Fahlbusch WD Müller A Petersen SI Lee S Vieths 2001 Monoclonal antibodies raised against the major apple allergen, Mal d 1, are useful tools for epitope studies Food Agric Immunol 13 1 39 49 1:CAS:528:DC%2BD3MXivFGmurY%3D 10.1080/09540100051074202