Circadian rhythm and cartilage extracellular matrix genes in osseointegration: A genome-wide screening of implant failure by vitamin D deficiency

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Mengatto, Cristiane Machado ^a,b   Mussano, Federico ^a,c   Honda, Yoshitomo ^a   Colwell, Christopher S ^d   Nishimura, Ichiro ^a  

^a UCLA SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; ALKALINE PHOSPHATASE; ALPHA 2C ADRENERGIC RECEPTOR; AROMATIC HYDROCARBON RECEPTOR; CALCIUM; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CATENIN; COLLAGEN TYPE 1; COLLAGEN TYPE 10; COLLAGEN TYPE 11; COLLAGEN TYPE 2; COLLAGEN TYPE 5; COLLAGEN TYPE 9; DERMATAN SULFATE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 1; HYALURONIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NEURONAL PAS DOMAIN 2; OSTEOCALCIN; OSTEONECTIN; OSTEOPONTIN; PER2 PROTEIN; SCLEROPROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; VISININ; VITAMIN D; TITANIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE REGENERATION; CALCIUM BLOOD LEVEL; CARTILAGE; CELL CULTURE; CIRCADIAN RHYTHM; CLUSTER ANALYSIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMUR; GENE IDENTIFICATION; GENETIC ASSOCIATION; GRAFT FAILURE; IMPLANT; MALE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OSTEOTOMY; PROTEIN DOMAIN; PROTEIN EXPRESSION; UPREGULATION; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; ANIMAL; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; GENOME; PHYSIOLOGY; PROSTHESIS FAILURE; RAT; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

RATTUS;

ANIMALS; CARTILAGE; CIRCADIAN RHYTHM; EXTRACELLULAR MATRIX; FEMUR; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENOME; GENOME-WIDE ASSOCIATION STUDY; IMPLANTS, EXPERIMENTAL; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSSEOINTEGRATION; PROSTHESIS FAILURE; RATS; RATS, SPRAGUE-DAWLEY; TITANIUM; VITAMIN D DEFICIENCY;

EID: 79251551355     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015848     Document Type: Article

References (58)

1. Albrektsson T, Albrektsson B (1987) Osseointegration of bone implants. A review of an alternative mode of fixation. Acta Orthop Scand 58: 567-577.
2. Marco F, Milena F, Gianluca G, Vittoria O (2005) Peri-implant osteogenesis in health and osteoporosis. Micron 36: 630-644.
3. Cooper LF, Masuda T, Yliheikkila PK, Felton DA (1998) Generalizations regarding the process and phenomenon of osseointegration. Part II. In vitro studies. Int J Oral Maxillofac Implants 13: 163-174.
4. Davies JE (2003) Understanding peri-implant endosseous healing. J Dent Educ 67: 932-949.
5. Schwartz Z, Nasazky E, Boyan BD (2005) Surface microtopography regulates osteointegration: the role of implant surface microtopography in osteointegration. Alpha Omegan 98: 9-19.
6. Carinci F, Pezzetti F, Volinia S, Francioso F, Arcelli D, et al. (2004) Analysis of MG63 osteoblastic-cell response to a new nanoporous implant surface by means of a microarray technology. Clin Oral Implants Res 15: 180-186.
7. Carinci F, Pezzetti F, Volinia S, Francioso F, Arcelli D, et al. (2003) Analysis of osteoblast-like MG63 cells' response to a rough implant surface by means of DNA microarray. J Oral Implantol 29: 215-220.
8. Kim CS, Sohn SH, Jeon SK, Kim KN, Ryu JJ, et al. (2006) Effect of various implant coatings on biological responses in MG63 using cDNA microarray. J Oral Rehabil 33: 368-379.
9. Kojima N, Ozawa S, Miyata Y, Hasegawa H, Tanaka Y, et al. (2008) Highthroughput gene expression analysis in bone healing around titanium implants by DNA microarray. Clin Oral Implants Res 19: 173-181.
10. Alvim-Pereira F, Montes CC, Mira MT, Trevilatto PC (2008) Genetic susceptibility to dental implant failure: a critical review. Int J Oral Maxillofac Implants 23: 409-416.
11. Holahan CM, Koka S, Kennel KA, Weaver AL, Assad DA, et al. (2008) Effect of osteoporotic status on the survival of titanium dental implants. Int J Oral Maxillofac Implants 23: 905-910.
12. Lekholm U (2003) Immediate/early loading of oral implants in compromised patients. Periodontol 2000 33: 194-203.
13. Econs MJ, Lobaugh B, Drezner MK (1992) Normal calcitonin stimulation of serum calcitriol in patients with X-linked hypophosphatemic rickets. J Clin Endocrinol Metab 75: 408-411.
14. Kelly J, Lin A, Wang CJ, Park S, Nishimura I (2009) Vitamin D and bone physiology: demonstration of vitamin D deficiency in an implant osseointegration rat model. J Prosthodont 18: 473-478.
15. Lin R, White JH (2004) The pleiotropic actions of vitamin D. Bioessays 26: 21-28.
16. Slominski A, Wortsman J (2000) Neuroendocrinology of the skin. Endocr Rev 21: 457-487.
17. Adams JS (2006) Vitamin D as a defensin. J Musculoskelet Neuronal Interact 6: 344-346.
18. Adams JS, Hewison M (2008) Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 4: 80-90.
19. Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M (2008) Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 122: 398-417.
20. Bar-Shavit Z, Kahn AJ, Teitelbaum SL (1983) Defective binding of macrophages to bone in rodent osteomalacia and vitamin D deficiency. In vitro evidence for a cellular defect and altered saccharides in the bone matrix. J Clin Invest 72: 526-534.
21. Heaney RP (2003) Long-latency deficiency disease: insights from calcium and vitamin D. Am J Clin Nutr 78: 912-919.
22. Reginster JY (2005) The high prevalence of inadequate serum vitamin D levels and implications for bone health. Curr Med Res Opin 21: 579-586.
23. de Abreu DA, Eyles D, Feron F (2009) Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases. Psychoneuroendocrinology 34 Suppl 1: S265-277.
24. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, et al. (2006) Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311: 1770-1773.
25. Holick MF (2006) Resurrection of vitamin D deficiency and rickets. J Clin Invest 116: 2062-2072.
26. Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, et al. (2009) Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 20: 1807-1820.
27. Hirani V, Tull K, Ali A, Mindell J (2010) Urgent action needed to improve vitamin D status among older people in England! Age Ageing 39: 62-68.
28. Saintonge S, Bang H, Gerber LM (2009) Implications of a new definition of vitamin D deficiency in a multiracial us adolescent population: the National Health and Nutrition Examination Survey III. Pediatrics 123: 797-803.
29. Hokugo A, Christensen R, Chung E, Sung E, Felsenfeld A.L, et al. (2010) Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res Epub ahead of print.
30. Mendes VC, Moineddin R, Davies JE (2009) Discrete calcium phosphate nanocrystalline deposition enhances osteoconduction on titanium-based implant surfaces. J Biomed Mater Res A 90: 577-585.
31. Ozawa S, Ogawa T, Iida K, Sukotjo C, Hasegawa H, et al. (2002) Ovariectomy hinders the early stage of bone-implant integration: histomorphometric, biomechanical, and molecular analyses. Bone 30: 137-143.
32. Nishimura I, Huang Y, Butz F, Ogawa T, Lin L, et al. (2007) Discrete deposition substrate microtopography accelerated osseointegration. Nanotechnology 18: 9.
33. Ogata H, Goto S, Sato K, Fujibuchi W, Bono H, et al. (1999) KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 27: 29-34.
34. Takahashi JS, Hong HK, Ko CH, McDearmon EL (2008) The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Genet 9: 764-775.
35. Panda S, Antoch MP, Miller BH, Su AI, Schook AB, et al. (2002) Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109: 307-320.
36. Schibler U (2009) The 2008 Pittendrigh/Aschoff lecture: peripheral phase coordination in the mammalian circadian timing system. J Biol Rhythms 24: 3-15.
37. Fu L, Patel MS, Bradley A, Wagner EF, Karsenty G (2005) The molecular clock mediates leptin-regulated bone formation. Cell 122: 803-815.
38. Miller BH, McDearmon EL, Panda S, Hayes KR, Zhang J, et al. (2007) Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci U S A 104: 3342-3347.
39. Borgs L, Beukelaers P, Vandenbosch R, Belachew S, Nguyen L, et al. (2009) Cell ''circadian'' cycle: new role for mammalian core clock genes. Cell Cycle 8: 832-837.
40. Lin A, Wang CJ, Kelly J, Gubbi P, Nishimura I (2009) The role of titanium implant surface modification with hydroxyapatite nanoparticles in progressive early bone-implant fixation in vivo. Int J Oral Maxillofac Implants 24: 808-816.
41. Mendes VC, Moineddin R, Davies JE (2007) The effect of discrete calcium phosphate nanocrystals on bone-bonding to titanium surfaces. Biomaterials 28: 4748-4755.
42. Iwasa F, Hori N, Ueno T, Minamikawa H, Yamada M, et al. (2009) Enhancement of osteoblast adhesion to UV-photofunctionalized titanium via an electrostatic mechanism. Biomaterials.
43. Le Guehennec L, Lopez-Heredia MA, Enkel B, Weiss P, Amouriq Y, et al. (2008) Osteoblastic cell behaviour on different titanium implant surfaces. Acta Biomater 4: 535-543.
44. Gu YZ, Hogenesch JB, Bradfield CA (2000) The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol 40: 519-561.
45. McIntosh BE, Hogenesch JB, Bradfield CA (2010) Mammalian Per-Arnt-Sim proteins in environmental adaptation. Annu Rev Physiol 72: 625-645.
46. Yang X, Downes M, Yu RT, Bookout AL, He W, et al. (2006) Nuclear receptor expression links the circadian clock to metabolism. Cell 126: 801-810.
47. Eisen MB, Spellman PT, Brown PO, Botstein D (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 95: 14863-14868.
48. Markway BD, Tan GK, Brooke G, Hudson JE, Cooper-White JJ, et al. (2009) Enhanced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in Low Oxygen Environment Micropellet Cultures. Cell Transplant.
49. Khan WS, Adesida AB, Tew SR, Lowe ET, Hardingham TE (2010) Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions. J Orthop Res.
50. Schipani E (2005) Hypoxia and HIF-1 alpha in chondrogenesis. Semin Cell Dev Biol 16: 539-546.
51. Zuscik MJ, Hilton MJ, Zhang X, Chen D, O'Keefe RJ (2008) Regulation of chondrogenesis and chondrocyte differentiation by stress. J Clin Invest 118: 429-438.
52. Seki K, Fujimori T, Savagner P, Hata A, Aikawa T, et al. (2003) Mouse Snail family transcription repressors regulate chondrocyte, extracellular matrix, type II collagen, and aggrecan. J Biol Chem 278: 41862-41870.
53. Hinoi E, Takarada T, Fujimori S, Wang L, Iemata M, et al. (2007) Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis. Bone 40: 337-344.
54. Kwan AP, Cummings CE, Chapman JA, Grant ME (1991) Macromolecular organization of chicken type X collagen in vitro. J Cell Biol 114: 597-604.
55. Zahurak M, Parmigiani G, Yu W, Scharpf RB, Berman D, et al. (2007) Preprocessing Agilent microarray data. BMC Bioinformatics 8: 142.
56. Devlin B, Roeder K, Wasserman L (2003) False discovery or missed discovery? Heredity 91: 537-538.
57. Hochberg Y, Benjamini Y (1990) More powerful procedures for multiple significance testing. Stat Med 9: 811-818.
58. Florell SR, Coffin CM, Holden JA, Zimmermann JW, Gerwels JW, et al. (2001) Preservation of RNA for functional genomic studies: a multidisciplinary tumor bank protocol. Mod Pathol 14: 116-128.