Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone

Journal of Orthopaedic Research

Volumn 29, Issue 3, 2011, Pages 354-360

  Hiraoka, Nobuyuki ^a   Takahashi, Kenji A ^a   Arai, Yuji ^a   Sakao, Kei ^a   Mazda, Osam ^a   Kishida, Tsunao ^a   Honjo, Kuniaki ^a   Tanaka, Sakae ^b   Kubo, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

hyaluronan; interleukin 6 (IL 6); matrix metalloproteinase 13 (MMP 13); osteoarthritis; subchondral bone

Indexed keywords

ANTIBODY; CD44 ANTIBODY; COLLAGENASE 3; HERMES ANTIGEN; HYALURONIC ACID; INTERLEUKIN 6; MESSENGER RNA; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; BONE MARROW CELL; BONE PLATE; CARTILAGE; CELL ADHESION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MORPHOLOGY; NONHUMAN; OSTEOARTHRITIS; OSTEOBLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD44; BONE MARROW; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; INTERLEUKIN-6; MATRIX METALLOPROTEINASE 13; OSTEOARTHRITIS, KNEE; OSTEOBLASTS; RABBITS; RNA, MESSENGER; VISCOSUPPLEMENTS;

EID: 79251549199     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21240     Document Type: Article

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