Active site modification of the β-ketoacyl-ACP synthase FabF3 of Streptomyces coelicolor affects the fatty acid chain length of the CDA lipopeptides

Chemical Communications

Volumn 47, Issue 6, 2011, Pages 1860-1862

  Lewis, Richard A ^a   Nunns, Laura ^b   Thirlway, Jenny ^b   Carroll, Kathleen ^b   Smith, Colin P ^a   Micklefield, Jason ^b  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; CALCIUM DEPENDENT ANTIBIOTIC AGENT; FABF3 PROTEIN; FATTY ACID; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; GENE CLUSTER; NONHUMAN; POLYMERIZATION; PROTEIN MODIFICATION; SITE DIRECTED MUTAGENESIS; STREPTOMYCES COELICOLOR;

EID: 79251503620     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c0cc03444d     Document Type: Article

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