-
3
-
-
0000529234
-
-
ed. A. Abell, JAI Press, Greenwich
-
J. Aubé, in Advances in Amino Acid Mimetics and Peptidomimetics ed., A. Abell, JAI Press, Greenwich, 1997, p. 193
-
(1997)
Advances in Amino Acid Mimetics and Peptidomimetics
, pp. 193
-
-
Aubé, J.1
-
4
-
-
0006077638
-
Synthesis of Medium-Sized Ring Lactams
-
U. Nubbemeyer Synthesis of Medium-Sized Ring Lactams Top. Curr. Chem. 2001 216 125
-
(2001)
Top. Curr. Chem.
, vol.216
, pp. 125
-
-
Nubbemeyer, U.1
-
10
-
-
0035950061
-
-
F. R. Kinder Jr. R. W. Versace K. W. Bair J. M. Bontempo D. Cesarz S. Chen P. Crews A. M. Czuchta C. T. Jagoe Y. Mou R. Nemzek P. E. Phillips L. D. Tran R. Wang S. Weltchek S. Zabludoff J. Med. Chem. 2001 44 3692
-
(2001)
J. Med. Chem.
, vol.44
, pp. 3692
-
-
Kinder Jr., F.R.1
Versace, R.W.2
Bair, K.W.3
Bontempo, J.M.4
Cesarz, D.5
Chen, S.6
Crews, P.7
Czuchta, A.M.8
Jagoe, C.T.9
Mou, Y.10
Nemzek, R.11
Phillips, P.E.12
Tran, L.D.13
Wang, R.14
Weltchek, S.15
Zabludoff, S.16
-
13
-
-
27644536727
-
-
Y. Shi J. Zhang P. D. Stein M. Shi S. P. O'Connor S. N. Bisaha C. Li K. S. Atwal G. S. Bisacchi D. Sitkoff A. T. Pudzianowski E. C. Liu K. S. Hartl S. M. Seiler S. Youssef T. E. Steinbacher W. A. Schumacher A. R. Rendina J. M. Bozarth T. L. Peterson G. Zhang R. Zahler Bioorg. Med. Chem. Lett. 2005 15 5453
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 5453
-
-
Shi, Y.1
Zhang, J.2
Stein, P.D.3
Shi, M.4
O'Connor, S.P.5
Bisaha, S.N.6
Li, C.7
Atwal, K.S.8
Bisacchi, G.S.9
Sitkoff, D.10
Pudzianowski, A.T.11
Liu, E.C.12
Hartl, K.S.13
Seiler, S.M.14
Youssef, S.15
Steinbacher, T.E.16
Schumacher, W.A.17
Rendina, A.R.18
Bozarth, J.M.19
Peterson, T.L.20
Zhang, G.21
Zahler, R.22
more..
-
25
-
-
0028233389
-
-
R. Polt F. Porreca L. Z. Szabo E. J. Bilsky P. Davis T. J. Abbruscato T. P. Davis R. Harvath H. I. Yamamura V. J. Hruby Proc. Natl. Acad. Sci. U. S. A. 1994 91 7114
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 7114
-
-
Polt, R.1
Porreca, F.2
Szabo, L.Z.3
Bilsky, E.J.4
Davis, P.5
Abbruscato, T.J.6
Davis, T.P.7
Harvath, R.8
Yamamura, H.I.9
Hruby, V.J.10
-
31
-
-
79251488622
-
-
20050153928
-
US Pat., 20050153928, 2005
-
(2005)
US Pat.
-
-
-
33
-
-
0036240316
-
-
See the ESI for detailed experimental information During the alkylation step, unwanted olefin II was obtained as a major compound. The spectral data of compound 3 prepared via this route was compared with that of 3 obtained by the Aubé reaction and found to be identical. Experimental details and all other unsuccessful attempts to prepare sugar-lactam conjugate 3 are available in the ESI HPLC analysis of the reaction mixture showed a >95:5 diastereoselectivity. Only the major isomer was isolated The stereochemistry of the newly formed chiral center in compound 9 is assumed to be as drawn based on the X-ray structure of the triacetate of 8
-
X. J. Wu X. Tang M. Xian P. G. Braunschweiger P. G. Wang Bioorg. Med. Chem. 2002 10 2303
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2303
-
-
Wu, X.J.1
Tang, X.2
Xian, M.3
Braunschweiger, P.G.4
Wang, P.G.5
-
35
-
-
0012409009
-
-
J. J. Kulagowski H. B. Broughton N. R. Curtis I. M. Mawer M. P. Ridgill R. Baker F. Emms S. Freedman R. Marwood S. Patel I. Ragan P. D. Leeson J. Med. Chem. 1996 39 1941
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1941
-
-
Kulagowski, J.J.1
Broughton, H.B.2
Curtis, N.R.3
Mawer, I.M.4
Ridgill, M.P.5
Baker, R.6
Emms, F.7
Freedman, S.8
Marwood, R.9
Patel, S.10
Ragan, I.11
Leeson, P.D.12
-
38
-
-
0025146271
-
-
K. C. Nicolaou C.-K. Hwang B. E. Marron S. DeFrces E. A. Couladouro Y. Abe P. J. Carrol J. P. Snyder J. Am. Chem. Soc. 1990 112 3040
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 3040
-
-
Nicolaou, K.C.1
Hwang, C.-K.2
Marron, B.E.3
Defrces, S.4
Couladouro, E.A.5
Abe, Y.6
Carrol, P.J.7
Snyder, J.P.8
-
41
-
-
79251473864
-
-
Along with 23 and 26, small amounts of corresponding cyclopentanone ketals VI (13%) and VII (21%) were also isolated, respectively. Their tentative structures are shown below: "chemical equation presented"
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Along with 23 and 26, small amounts of corresponding cyclopentanone ketals VI (13%) and VII (21%) were also isolated, respectively. Their tentative structures are shown below: "chemical equation presented"
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