Lectin-mediated drug targeting: Discrimination of carbohydrate-mediated cellular uptake between tumor and liver cells with neoglycoconjugates carrying fucose epitopes regioselectively modified in the 3-position

Angewandte Chemie - International Edition

Volumn 38, Issue 24, 1999, Pages 3680-3683

  Lerchen, Hans Georg ^a   Baumgarten, Joerg ^a   Piel, Norbert ^b   Kolb Bachofen, Victoria ^c  

^a BAYER AG   (Germany)

^b BAYER CORPORATION   (United States)

^c Forschungsgruppe Immunbiologie H   (Germany)

Author keywords

Carbohydrates; Drug research; Endocytosis; Glycoproteins; Tumor therapy

Indexed keywords

BATRACYLIN; BOVINE SERUM ALBUMIN; CARBOHYDRATE; EPITOPE; FUCOSE; LECTIN;

ARTICLE; CYTOTOXICITY; DRUG BINDING; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; HUMAN; HUMAN CELL; LIVER CELL; TUMOR CELL;

EID: 0033576660     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991216)38:24<3680::AID-ANIE3680>3.0.CO;2-9     Document Type: Article

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