Cell-cycle regulators cdk2ap1 and bicalutamide suppress malignant biological interactions between prostate cancer and bone cells

Prostate

Volumn 71, Issue 4, 2011, Pages 353-367

  Zolochevska, Olga ^a   Figueiredo, Marxa L ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

bicalutamide; bone interaction; cdk2ap1; cell cycle regulation; prostate cancer; therapy

Indexed keywords

BICALUTAMIDE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 ASSOCIATED PROTEIN 1; LENTIVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE CELL; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; COCULTURE; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MICROENVIRONMENT; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION; STABLE EXPRESSION;

ANILIDES; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; G1 PHASE; HUMANS; MALE; MICE; NEOPLASM INVASIVENESS; NF-KAPPA B; NITRILES; OSTEOCLASTS; PROSTATIC NEOPLASMS; S PHASE; SIGNAL TRANSDUCTION; TOSYL COMPOUNDS; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS;

EID: 79251494459     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21249     Document Type: Article

References (42)

1. Schroder FH,. Endocrine therapy for prostate cancer: Recent developments and current status. Br J Urol 1993; 71 (6): 633-640.
2. Culig Z, Klocker H, Eberle J, Kaspar F, Hobisch A, Cronauer MV, Bartsch G,. DNA sequence of the androgen receptor in prostatic tumor cell lines and tissue specimens assessed by means of the polymerase chain reaction. Prostate 1993; 22 (1): 11-22.
3. Rigas AC, Robson CN, Curtin NJ,. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer. Oncogene 2007; 26 (55): 7611-7619.
4. Katner AL, Hoang QB, Gootam P, Jaruga E, Ma Q, Gnarra J, Rayford W,. Induction of cell cycle arrest and apoptosis in human prostate carcinoma cells by a recombinant adenovirus expressing p27(Kip1). Prostate 2002; 53 (1): 77-87.
5. Zolochevska O, Figueiredo ML,. Cell cycle regulator cdk2ap1 inhibits prostate cancer cell growth and modifies androgen-responsive pathway function. Prostate 2009; 69 (14): 1586-1597.
6. Shintani S, Ohyama H, Zhang X, McBride J, Matsuo K, Tsuji T, Hu MG, Hu G, Kohno Y, Lerman M, Todd R, Wong DT,. p12(DOC-1) is a novel cyclin-dependent kinase 2-associated protein. Mol Cell Biol 2000; 20 (17): 6300-6307.
7. Shintani S, Mihara M, Terakado N, Nakahara Y, Matsumura T, Kohno Y, Ohyama H, McBride J, Kent R, Todd R, Tsuji T, Wong DT,. Reduction of p12DOC-1 expression is a negative prognostic indicator in patients with surgically resected oral squamous cell carcinoma. Clin Cancer Res 2001; 7 (9): 2776-2782.
8. Figueiredo M, Kim Y, St John MAR, Wong DTW,. p12CDK2AP1 gene therapy strategy inhibits tumor growth in an in vivo mouse model of head and neck cancer. Clin Cancer Res 2005; 11 (10): 3939-3948.
9. Tao K, Fang M, Alroy J, Sahagian GG,. Imagable 4T1 model for the study of late stage breast cancer. BMC Cancer 2008; 8: 228.
10. Sotsky Kent T, Yuan Z, Miller A, Weber TK,. Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer. Ann Surg Oncol 2004; 11 (2): 192-196.
11. Yuan Z, Sotsky Kent T, Weber TK,. Differential expression of DOC-1 in microsatellite-unstable human colorectal cancer. Oncogene 2003; 22 (40): 6304-6310.
12. Matsuo K, Shintani S, Tsuji T, Nagata E, Lerman M, McBride J, Nakahara Y, Ohyama H, Todd R, Wong DT,. p12(DOC-1), a growth suppressor, associates with DNA polymerase alpha/primase. FASEB J 2000; 14 (10): 1318-1324.
13. Cwikla SJ, Tsuji T, McBride J, Wong DT, Todd R,. doc-1-Mediated apoptosis in malignant hamster oral keratinocytes. J Oral Maxillofac Surg 2000; 58 (4): 406-414.
14. Kohno Y, Patel V, Kim Y, Tsuji T, Chin BR, Sun M, Bruce Donoff R, Kent R, Wong D, Todd R,. Apoptosis, proliferation and p12(doc-1) profiles in normal, dysplastic and malignant squamous epithelium of the Syrian hamster cheek pouch model. Oral Oncol 2002; 38 (3): 274-280.
15. Arencibia JM, Martin S, Perez-Rodriguez FJ, Bonnin A,. Gene expression profiling reveals overexpression of TSPAN13 in prostate cancer. Int J Oncol 2009; 34 (2): 457-463.
16. Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR,. Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci USA 2001; 98 (26): 15149-15154.
17. Nanni S, Priolo C, Grasselli A, D'Eletto M, Merola R, Moretti F, Gallucci M, De Carli P, Sentinelli S, Cianciulli AM, Mottolese M, Carlini P, Arcelli D, Helmer-Citterich M, Gaetano C, Loda M, Pontecorvi A, Bacchetti S, Sacchi A, Farsetti A,. Epithelial-restricted gene profile of primary cultures from human prostate tumors: A molecular approach to predict clinical behavior of prostate cancer. Mol Cancer Res 2006; 4 (2): 79-92.
18. Lin B, White JT, Lu W, Xie T, Utleg AG, Yan X, Yi EC, Shannon P, Khrebtukova I, Lange PH, Goodlett DR, Zhou D, Vasicek TJ, Hood L,. Evidence for the presence of disease-perturbed networks in prostate cancer cells by genomic and proteomic analyses: A systems approach to disease. Cancer Res 2005; 65 (8): 3081-3091.
19. Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L,. A third-generation lentivirus vector with a conditional packaging system. J Virol 1998; 72 (11): 8463-8471.
20. Koponen JK, Kankkonen H, Kannasto J, Wirth T, Hillen W, Bujard H, Ylä-Herttuala S,., Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo. Gene Ther 2003; 10 (6): 459-466.
21. Soneoka Y, Cannon PM, Ramsdale EE, Griffiths JC, Romano G, Kingsman SM, Kingsman AJ,. A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids Res 1995; 23 (4): 628-633.
22. Sastry L, Johnson T, Hobson MJ, Smucker B, Cornetta K,. Titering lentiviral vectors: Comparison of DNA, RNA and marker expression methods. Gene Ther 2002; 9 (17): 1155-1162.
23. Pluta K, Diehl W, Zhang XY, Kutner R, Bialkowska A, Reiser J,. Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: A comparative study. BMC Biotechnol 2007; 7: 41.
24. Wu Z, McRoberts KS, Theodorescu D,. The role of PTEN in prostate cancer cell tropism to the bone micro-environment. Carcinogenesis 2007; 28 (7): 1393-1400.
25. Zhan P, Lee EC, Packman K, Tenniswood M,. Induction of invasive phenotype by Casodex in hormone-sensitive prostate cancer cells. J Steroid Biochem Mol Biol 2002; 83 (1-5): 101-111.
26. Yin J, Pollock C, Tracy K, Chock M, Martin P, Oberst M, Kelly K,. Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Mol Cell Biol 2007; 27 (21): 7538-7550.
27. Fisher JL, Schmitt JF, Howard ML, Mackie PS, Choong PF, Risbridger GP,. An in vivo model of prostate carcinoma growth and invasion in bone. Cell Tissue Res 2002; 307 (3): 337-345.
28. Mori K, Le Goff B, Charrier C, Battaglia S, Heymann D, Redini F,. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: New insights in the prostate cancer bone metastasis process. Bone 2007; 40 (4): 981-990.
29. Floryk D, Huberman E,. Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity. Cancer Res 2005; 65 (24): 11588-11596.
30. Floryk D, Tollaksen SL, Giometti CS, Huberman E,. Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5′-monophosphate dehydrogenase. Cancer Res 2004; 64 (24): 9049-9056.
31. Davis JN, Wojno KJ, Daignault S, Hofer MD, Kuefer R, Rubin MA, Day ML,. Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer. Cancer Res 2006; 66 (24): 11897-11906.
32. Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M,. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis. Prostate 2006; 66 (1): 70-81.
33. Tyagi A, Agarwal C, Agarwal R,. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells. Cell Cycle 2002; 1 (2): 137-142.
34. Sitcheran R, Cogswell PC, Baldwin AS Jr., NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes Dev 2003; 17 (19): 2368-2373.
35. Lampen A, Leifheit M, Voss J, Nau H,. Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: Effects on proliferation, differentiation, and gene expression. Biochim Biophys Acta 2005; 1735 (1): 30-40.
36. Oldak M, Maksym RB, Sperling T, Yaniv M, Smola H, Pfister HJ, Malejczyk J, Smola S,. Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes. J Virol 84 (3): 1376-1386.
37. Wagner EF,. Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun). Ann Rheum Dis 2010; 69 (Suppl 1): i86-i88.
38. Erlebacher A, Filvaroff EH, Ye JQ, Derynck R,. Osteoblastic responses to TGF-beta during bone remodeling. Mol Biol Cell 1998; 9 (7): 1903-1918.
39. Hall CL, Kang S, MacDougald OA, Keller ET,. Role of Wnts in prostate cancer bone metastases. J Cell Biochem 2006; 97 (4): 661-672.
40. Dai J, Kitagawa Y, Zhang J, Yao Z, Mizokami A, Cheng S, Nor J, McCauley LK, Taichman RS, Keller ET,. Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein. Cancer Res 2004; 64 (3): 994-999.
41. Ritchie CK, Andrews LR, Thomas KG, Tindall DJ, Fitzpatrick LA,. The effects of growth factors associated with osteoblasts on prostate carcinoma proliferation and chemotaxis: Implications for the development of metastatic disease. Endocrinology 1997; 138 (3): 1145-1150.
42. Graham TR, Agrawal KC, Abdel-Mageed AB,. Independent and cooperative roles of tumor necrosis factor-alpha, nuclear factor-kappaB, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of MC3T3-E1 osteoblast-like cells. Cancer Sci 101 (1): 103-111.