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Volumn 1, Issue 2, 2002, Pages 122-127
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The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells.
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTINEOPLASTIC AGENT;
CDK2 PROTEIN, HUMAN;
CDK4 PROTEIN, HUMAN;
CDKN1A PROTEIN, HUMAN;
CDKN2B PROTEIN, HUMAN;
CELL CYCLE PROTEIN;
CYCLIN DEPENDENT KINASE;
CYCLIN DEPENDENT KINASE 2;
CYCLIN DEPENDENT KINASE 4;
CYCLIN DEPENDENT KINASE INHIBITOR 1A;
CYCLIN DEPENDENT KINASE INHIBITOR 1B;
CYCLIN DEPENDENT KINASE INHIBITOR 2B;
CYCLINE;
DNA BINDING PROTEIN;
E2F4 PROTEIN, HUMAN;
FLAVONOID;
NUCLEAR PROTEIN;
ONCOPROTEIN;
PHOSPHOPROTEIN;
PROTEIN;
PROTEIN P107;
PROTEIN P130;
PROTEIN P16INK4A;
PROTEIN SERINE THREONINE KINASE;
RBL1 PROTEIN, HUMAN;
RBL2 PROTEIN, HUMAN;
SILIBININ;
SILYMARIN;
TRANSCRIPTION FACTOR;
TRANSCRIPTION FACTOR E2F;
TRANSCRIPTION FACTOR E2F3;
TRANSCRIPTION FACTOR E2F4;
TRANSCRIPTION FACTOR E2F5;
TUMOR SUPPRESSOR PROTEIN;
ARTICLE;
BIOSYNTHESIS;
CELL CULTURE;
CELL CYCLE;
CELL CYCLE G1 PHASE;
CELL DIFFERENTIATION;
CELL DIVISION;
CHEMICAL STRUCTURE;
CHEMISTRY;
DRUG EFFECT;
HUMAN;
MALE;
METABOLISM;
PHOSPHORYLATION;
PROSTATE TUMOR;
ANTICARCINOGENIC AGENTS;
CDC2-CDC28 KINASES;
CELL CYCLE;
CELL CYCLE PROTEINS;
CELL DIFFERENTIATION;
CELL DIVISION;
CYCLIN-DEPENDENT KINASE 2;
CYCLIN-DEPENDENT KINASE 4;
CYCLIN-DEPENDENT KINASE INHIBITOR P15;
CYCLIN-DEPENDENT KINASE INHIBITOR P16;
CYCLIN-DEPENDENT KINASE INHIBITOR P21;
CYCLIN-DEPENDENT KINASE INHIBITOR P27;
CYCLIN-DEPENDENT KINASES;
CYCLINS;
DNA-BINDING PROTEINS;
E2F TRANSCRIPTION FACTORS;
E2F3 TRANSCRIPTION FACTOR;
E2F4 TRANSCRIPTION FACTOR;
E2F5 TRANSCRIPTION FACTOR;
FLAVONOIDS;
G1 PHASE;
HUMANS;
MALE;
MOLECULAR STRUCTURE;
NUCLEAR PROTEINS;
PHOSPHOPROTEINS;
PHOSPHORYLATION;
PROSTATIC NEOPLASMS;
PROTEIN-SERINE-THREONINE KINASES;
PROTEINS;
PROTO-ONCOGENE PROTEINS;
RETINOBLASTOMA-LIKE PROTEIN P107;
RETINOBLASTOMA-LIKE PROTEIN P130;
SILYMARIN;
TRANSCRIPTION FACTORS;
TUMOR CELLS, CULTURED;
TUMOR SUPPRESSOR PROTEINS;
MLCS;
MLOWN;
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EID: 0036490927
PISSN: 15384101
EISSN: None
Source Type: Journal
DOI: 10.4161/cc.1.2.115 Document Type: Article |
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Times cited : (14)
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References (0)
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