Obesity, longevity, quality of life alteration by dietary 2-mercaptoethanol

Virulence

Volumn 1, Issue 6, 2010, Pages 509-515

  Click, Robert E ^a  

^a VA MEDICAL CENTER   (United States)

Author keywords

2 mercaptoethanol; In situ; Longevity; Obesity

Indexed keywords

DRINKING WATER; MERCAPTOETHANOL;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CACHEXIA; CONTROLLED STUDY; DRINKING; IMMUNOREACTIVITY; INDIVIDUALIZATION; LIFESPAN; LONGEVITY; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION POTENTIAL; QUALITY OF LIFE; SURVIVAL; TISSUE CULTURE; WEIGHT REDUCTION;

ANIMALIA; MURINAE; MUS;

EID: 79251474684     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.1.6.13803     Document Type: Article

References (72)

1. Cleland WW. Dithiothreitol, a new protective reagent for SH groups. Biochemistry 1964; 3:480-2.
2. Alliegro MC. Effects of dithiothreitol on protein activity unrelated to thiol-disulfide exchange: For consideration in the analysis of protein function with Cleland's reagent. Anal Biochem 2000; 15:102-6.
3. Mishell RI, Dutton RW. Immunization of dissociated spleen cell cultures from normal mice. J Exp Med 1967; 126:423-42.
4. Click RE, Benck L, Alter BJ. Enhancement of antibody synthesis in vitro by mercaptoethanol. Cell Immunol 1972; 3:156-60.
5. Click RE, Benck L, Alter BJ. Immune responses in vitro. I. Culture conditions for antibody synthesis. Cell Immunol 1972; 3:264-76.
6. Heber-Katz E, Click RE. Immune responses in vitro. V. Role of mercaptoethanol in the mixed-leukocyte reaction. Cell Immunol 1972; 5:410-8.
7. Katz-Heber E, Peck AB, Click RE. Immune responses in vitro. II. Mixed leukocyte interaction in a proteinfree medium. Eur J Immunol 1973; 3:379-85.
8. Peck AB, Click RE. Immune responses in vitro. III. Enhancement of the mouse mixed lymphocyte interaction by isologous and homologous sera. Eur J Immunol 1973; 3:385-92.
9. Chen C, Hirsch JG. The effects of mercaptoethanol and of peritoneal macrophages on the antibody-forming capacity of nonadherant mouse spleen cells in vitro. J Exp Med 1972; 136:604-17.
10. Bevan MJ, Epstein R, Cohn M. The effect of 2-mercaptoethanol on murine mixed lymphocyte cultures. J Exp Med 1974; 139:1025-30.
11. Ohmori H, Yamamoto I. Activation of murine lymphocytes by 2-mercaptoethanol and related thiol compounds and its mechanism. I. Relationship between mitogenic activities and augmenting effects on antibody synthesis in vitro. Immunopharmacol 1981; 3:333-45.
12. Makinodan T, Albright JW. Restoration of impaired immune functions in aging animals. II. Effect of mercaptoethanol in enhancing the reduced primary antibody responsiveness in vitro. Mech Ageing Dev 1979; 10:325-40.
13. Pisko EJ, Panetti M, Foster SL, Turner RA. Human rheumatoid factor-producing cells induced by 2-mercaptoetanol: immunomodulation by a simple thiol compound. Int J Immunopharmacol 1983; 5:163-70.
14. Gougerot-Pocidalo MA, Fay M, Roche Y, Chollet- Martin S. Mechanism by which oxdative injury inhibits the proliferative response of human lymphocytes to PHA. Effect of the thiol compound 2-mercaptoethanol. Immunol 1988; 64:281-8.
15. Stabel JR, Reinhardt TA, Nonnecke BJ. Effect of selenium and reducing agents on in vitro immunoglobulin M synthesis by bovine lymphocytes. J Dairy Sci 1991; 74:2501-6.
16. Messina JP, Lawrence DA. Effects of 2-mercaptoethanol and buthionine sulfoximine on cystine metabolism by and proliferation of mitogen-stimulated human and mouse lymphocytes. Int J Immunopharmacol 1992; 14:1221-34.
17. DeGuise S, Bernier J, Dufresne MM, Martineau D, Beland P, Fournier M. Immune functions in beluga whales (Delphinapterus leucas): Evaluation of mitogeninduced blastic transformation of lymphocytes from peripheral blood, spleen and thymus. Vet Immunol Immunopathol 1996; 50:117-26.
18. Abeydeera LR, Wang WH, Cantley TC, Prather RS, Day BN. Presence of beta-2 mercaptoethanol can increase the glutathione content of pig oocytes matured in vitro and the rate of blastocyst development after in vitro fertilization. Theriogenology 1998; 50:747-56.
19. Geshi M, Yonai M, Sakaguchi M, Nagai T. Improvement of in vitro co-culture systems for bovine embryos using a low concentration of carbon dioxide and medium supplemented with beta-mercaptoethanol. Theriogenology 1999; 51:551-8.
20. Feugang JM, de Roover R, Moens A, Leonard S, Dessy F, Donnay I. Addition of beta-mercaptoethanol or Trolox at the morula/blastocyst stage improves the quality of bovine blastocysts and prevents induction of apoptosis and degeneration by prooxidant agents. Theriogenology 2004; 61:71-90.
21. Bagis H, Odaman MH. Effect of chemically defined culture medium supplemented with beta-mercaptoethanol and amino acids on implantation and development of different stage in vivo- or in vitro-derived mouse embryos. Mol Reprod Dev 2004; 69:52-9.
22. Deneke SM. Thiol-based antioxidants. Curr Top Cell Regul 2000; 36:151-80.
23. Heidrick ML, Hendricks LC, Cook DE. Effect of dietary 2-mercaptoethaol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mech Ageing Dev 1984; 27:341-58.
24. Herman D. Free radical theory of aging: Beneficial effect of antioxidants on the life span of male NZB mice; role of free radical reactions in the deterioration of the immune system with age and in the pathogenesis of systemic lupus erythematosus. Age 1980; 3:64-73.
25. Zmuda J, Friedenson B. Changes in intracellular glutathione levels in stimulated and unstimulated lymphocytes in the presence of 2-mercaptoethaol or cysteine. J Immunol 1983; 130:362-4.
26. Hoffeld J, Oppenheim JJ. Enhancement of the primary antibody response by 2-mercapto-ethanol is mediated by its action on glutathione in the serum. Eur J Immunol 1980; 10:391-5.
27. Sido B, Braunstein J, Breitkreutz R, Herfarth C, Meuer SC. Thiol-mediated redox regulation of intestinal lamina propria T lymphocytes. J Exp Med 2000; 192:907-12.
28. Atkuri KR, Mantovani JJ, Herzenberg LA, Herzenberg LA. N-acetylcysteine-a safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol 2007; 7:355-9.
29. Ryzewski J, Roszkowski-Sliz W, Krzystyniak K. The action of thiols on lymphocyte membranes. Immunology 1976; 31:145-9.
30. Noelle RJ, Lawrence DA. Modulation of T-cell function. II. Chemical basis for the involvement of cell surface thiol-reactive sites in control of T-cell proliferation. Cell Immunol 1981; 60:453-69.
31. Ristow SS, Starkey JR, Stanford DR, Davis WC, Brooks CG. Cell surface thiols, but not intracellular glutathione, are essential for cytolysis by a cloned murine natural killer cell line. Immunol Invest 1985; 14:401-14.
32. Lawrence DA, Song R, Weber P. Surface thiols of human lymphocytes and their changes after in vitro and in vivo activation. Leukoc Biol 1996; 60:611-8.
33. Donoghue N, Yam PT, Jiang XM, Hogg PJ. Presence of closely spaced protein thiols on the surface of mammalian cells. Protein Sci USA 2000; 9:2436-45.
34. Sahaf B, Heydari K, Herzenberg LA, Herzenberg LA. Lymphocyte surface thiol levels. Proc Natl Acad Sci USA 2003; 100:4001-5.
35. Harman D. The free radical theory of aging: the effect of age on serum mercaptan levels. J Gerontol 1960; 15:38-40.
36. Leto S, Yiengst MJ, Barrows CH Jr. The effect of age and protein deprivation on the sulphydryl content of serum albumin. J Gerontol 1970; 25:4-8.
37. White K, Bruckner JV, Guess WL. Toxicological studies of 2-mercaptoethanol. J Pharm Sci 1973; 62:237-41.
38. Beregi E, Regius O, Rajczy K, Boross M, Penzes L. Effect of cigarette smoke and 2-mercaptoethanol administration on age-related alterations and immunological parameters. Gerontol 1991; 37:326-34.
39. Makinodan T, Albright JW. Restoration of impaired immune functions in aging animals. III. Effect of mercaptoethanol in enhancement of the reduced primary antibody responsiveness in vivo. Mech Ageing Dev 1979; 11:1-8.
40. Fischer HD, Wustmann C, Rudolph E, Oehler J, Jahkel M, Rostock A, et al. Effect of 2-mercaptoethanol on posthypoxic and age related biochemical and behavioral changes in mice and rats. Biomed Biochim Acta 1990; 49:1085-90.
41. Mukai FH, Goldstein BD. Mutagenicity of malonaldehyde, decomposition product of peroxidized polyunsaturated fatty acids. Science 1976; 191:868-9.
42. Durand G, Desnoyers F. Polyunsaturated fatty acids and aging. Lipofuscins: structure, origin and development. Ann Nutr Aliment 1980; 34:317-32.
43. Brunk UT, Terman A. Lipofuscin: mechanisms of agerelated accumulation and influence on cell function. Free Radic Biol Med 2002; 33:611-9.
44. Miquel J, Oro J, Bensch KG, Johnson JE. In: Pryor WA, Ed. Free Radicals in Biology Vol III. New York; Academic Press 55-73.
45. Pryor WA. The formation of free radicals and the consequences of their reactions in vivo. Photochem Photobiol 1978; 28:787-801.
46. McKeown MJ, Hall ND, Corvaian JR. Defective monocyte accessory function due to surface sulphydryl oxidation in rheumatoid arthritis. Clin Exp Immunol 1984; 56:607-13.
47. Brown-Galatola CH, Hall ND. Impaired suppressor cell activity due to surface sulphydryl oxidation in rheumatoid arthritis. Br J Rheumatol 1992; 31:599-603.
48. Yoda Y, Nakazawa M, Abe T, Kawakami Z. Prevention of doxorubicin myocardial toxicity in mice by reduced glutathione. Cancer Res 1986; 46:2551-6.
49. Dietzmann J, Thiel U, Ansorge S, Neumann KH, Tager M. Thiol-inducing and immunoregulatory effects of flavonoids in peripheral blood mononuclear cells from patients with end-stage diabetic nephropathy. Free Radic Biol Med 2002; 33:1347-54.
50. Atkuri KR, Cowan TM, Kwan T, Ng A, Herzenberg LA, Herzenberg LA, et al. Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia. Proc Natl Acad Sci USA 2009; 106:3941-4.
51. Demedts M, Behr J, Buhl R, Costabel U, Dekhuijzen R, Jansen HM, et al. For the IFIGENIA Study Group. High-dose acetylcysteine in idiopathic pulmonary fibrosis. New Engl J Med 2005; 353:2229-42.
52. Herzenberg LA, De Rosa SC, Dubs JG, Roederer M, Anderson MT, Ela SW, et al. Glutathione deficiency is associated with impaired survival in HIV disease. Proc Natl Acad Sci 2005; 94:1967-72.
53. Cayota A, Vuillier F, Gonzalez G, Dighiero G. In vitro antioxidant treatment recovers proliferative responses of anergic CD4+ lymphocytes from human immunodeficiency virus-infected individuals. Blood 1996; 87:4746-53.
54. Matthias LJ, Hogg PJ. Redox control on the cell surface: implications for HIV-1 entry. Antioxid Redox Signal 2003; 5:133-8.
55. Ho WZ, Douglas SD. Glutathione and N-acetylcysteine suppression of human immunodeficiency virus replication in human monocyte/macrophages in vitro. AIDS Res Hum Retroviruses 1992; 8:1249-53.
56. Staal FJ, Roederer M, Raju PA, Anderson MT, Ela SW, Herzenberg LA, et al. Antioxidants inhibit stimulation of HIV transcription. AIDS Res Hum Retroviruses 1993; 9:299-306.
57. Reliene R, Fleming SM, Chesselet MF, Schiestl RH. Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol 2008; 46:1371-7.
58. Kinnunen S, Oksala N, Hyyppa S, Sen CK, Radak Z, Laaksonen DE, et al. alpha-Lipoic acid modulates thiol antioxidant defences and attenuates exercise-induced oxidative stress in standardbred trotters. Free Radic Res 2009; 22:1-9.
59. Harris SB, Weindruch R, Smith GS, Mickey MR, Walford RL. Dietary restriction alone and in combination with oral ethoxyquin/2mercaptoethylamine in mice. J Gerontol 1990; 45:141-7.
60. Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003; 421:182-7.
61. Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth GS. Longevity: Extendng the lifespan of long-lived mice. Nature 2001; 414:412.
62. Jiang G, Li Z, Liu F, Ellsworth K, Dallas-Yang Q, Wu M, et al. Prevention of obesity in mice by antisense oligonucleotide inhibitors of steraroyl-CoA desaturase-1. J Clin Invest 2005; 115:1030-8.
63. Bhattacharya A, Rahman MM, McCarter R, O'Shea M, Fernandes G. Conjugated linoleic acid and chromium lower body weight and visceral fat mass in highfat-diet-fed mice. Lipids 2006; 41:437-44.
64. Yen CLE, Cheong ML, Grueter C, Zhou P, Moriwaki J, Wong JS, et al. Deficiency of the intestinal enzyme acyl CoA: mono-acylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nature Med 2009; 15:442-6.
65. Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic diseases. Curr Pharm Des 2009; 15:1546-58.
66. Duarte-Vazquez MA, Garcia-Padilla S, Olvera-Ochoa L, Gonzalez-Romero KE, Acosta-Iniguez J, De la Cruz-Cordero R, et al. Effect of protamine in obesity induced by high-fat diets in rats. Int J Obes (Lond) 2009; 33:687-92.
67. Miyawaki K, Yamada Y, Ban N, Ihara Y, Tsukiyama K, Zhou H, et al. Inhibition of gastric inhibitory polypepetide signaling prevents obesity. Nature Med 2002; 8:738-42.
68. Plum L, Lin HV, Dutia R, Tanaka J, Aizawa KS, Matsumoto M, et al. The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake. Nature Med 2009; 15:1195-201.
69. Prieto-Hontoria PL, Perez-Matute P, Fernandez-Galilea M, Barber A, Martinez JA, Moreno-Aliaga MJ. Lipoic acid prevents body weight gain induced by a high fat diet in rats: effects on intestinal sugar transport. Physiol Biochem 2009; 65:43-50.
70. Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clinical Invest 2006; 116:115-24.
71. Fletcher BL, Dillard CJ, Tappel AL. Measurement of fluorescent lipid peroxidation products in biological systems and tissues. Anal Biochem 1973; 52:1-9.
72. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metabolism 2008; 8:157-68.