The zinc-dependent protease activity of the botulinum neurotoxins

Toxins

Volumn 2, Issue 5, 2010, Pages 978-997

  Lebeda, Frank J ^a   Cer, Regina Z ^b   Mudunuri, Uma ^b   Stephens, Robert ^b   Singh, Bal Ram ^c   Adler, Michael ^d  

^a U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

^b SAIC FREDERICK INC   (United States)

^c UNIVERSITY OF MASSACHUSETTS DARTMOUTH   (United States)

^d US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Catalysis; Energy; kcat; Km; Superactivation

Indexed keywords

BOTULINUM TOXIN; NEUTRAL PROTEINASE; SNARE PROTEIN;

COMPUTER PROGRAM; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; THERMODYNAMICS; TOXIN ANALYSIS;

BOTULINUM TOXINS; KINETICS; NEUROTOXINS; PEPTIDE HYDROLASES; PROTEIN CONFORMATION; SNARE PROTEINS; ZINC;

EID: 79251468883     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins2050978     Document Type: Review

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