Evaluation of phosphoramidon and three synthetic phosphonates for inhibition of botulinum neurotoxin B catalytic activity

Journal of Applied Toxicology

Volumn 19, Issue SUPPL. 1, 1999, Pages

  Adler, Michael ^a   Nicholson, James D ^b   Starks, David F ^c   Kane, Charles T ^c   Cornille, Fabrice ^d   Hackley Jr , Brennie E ^e  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b Astrox Corporation   (United States)

^c Starks Associates Inc   (United States)

^d Laboratoire de Pharmacochimie   (France)

^e NONE

Author keywords

Botulinum neurotoxin B; Phosphonate monoesters; Phosphoramidon; Synaptobrevin 2; Zinc metalloprotease

Indexed keywords

AMINO ACID; BOTULINUM TOXIN; METALLOPROTEINASE INHIBITOR; PHENYL GROUP; PHOSPHONIC ACID DERIVATIVE; PHOSPHORAMIDON; RHAMNOSE; SYNAPTOBREVIN;

AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; ENZYME ACTIVITY; FLUORESCENCE; PRIORITY JOURNAL;

BOTULINUM TOXINS; CATALYSIS; GLYCOPEPTIDES; METALLOENDOPEPTIDASES; PHOSPHONIC ACIDS; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC SULFATE;

EID: 0033391217     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199912)19:1+3.0.CO;2-M     Document Type: Conference Paper

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