Heparin affinity of factor VIIa: Implications on the physiological inhibition by antithrombin and clearance of recombinant factor VIIa

Thrombosis Research

Volumn 127, Issue 2, 2011, Pages 154-160

  Martinez Martinez I ^a   Ordonez A ^a   Pedersen, S ^b   De La Morena Barrio, M E ^a   Navarro Fernandez J ^a   Kristensen, S R ^b   Minano A ^a   Padilla, J ^a   Vicente, V ^a   Corral, J ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Factor VIIa; FVIIa; LMWH; Low molecular weight heparin; recombinant FVIIa; Response units; rFVIIa; RU; SPR; Surface Plasmon resonance; TF; TFPI; Tissue Factor; Tissue factor pathway inhibitor; UHF; Unfractionated heparin

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 7A; CALCIUM ION; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; PENTASACCHARIDE; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; CONFORMATIONAL TRANSITION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IONIC STRENGTH; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN STRUCTURE;

ANIMALS; ANTITHROMBINS; CELL LINE, TUMOR; ENDOTHELIAL CELLS; FACTOR VIIA; HEPARIN; HUMANS; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE;

EID: 79151484179     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.11.008     Document Type: Article

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