Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors

Thrombosis and Haemostasis

Volumn 101, Issue 5, 2009, Pages 818-826

  Petersen, Lars C ^a   Elm, Torben ^a   Ezban, Mirella ^a   Krogh, Thomas N ^a   Karpf, Ditte M ^a   Steinø, Anne ^a   Olsen, Eva H N ^b   Sørensen, Brit B ^a  

^a NOVO NORDISK A S   (Denmark)

^b NOVO NORDISK INC   (United States)

Author keywords

Alpha2 macroglobulin; Antithrombin; Clearance; Complex formation; Factor VIIa

Indexed keywords

ALPHA 2 MACROGLOBULIN; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; HEPARIN; IODINE 125;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BOLUS INJECTION; COMPARATIVE STUDY; COMPLEX FORMATION; DRUG ACCUMULATION; DRUG BINDING SITE; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VIVO STUDY; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ALPHA-MACROGLOBULINS; ANIMALS; ANTITHROMBIN III; FACTOR VII; FACTOR VIIA; HEPARIN; HUMANS; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SERUM GLOBULINS;

EID: 66149175575     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-10-0699     Document Type: Article

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