Inhibitory effect of siRNA targeting IGF-1R on endometrial carcinoma

International Immunopharmacology

Volumn 11, Issue 2, 2011, Pages 244-249

  Shu, Shanrong ^a   Li, Xiaomao ^a   Yang, Yuebo ^a   Zhang, Yu ^a   Li, Tian ^a   Liang, Changyan ^a   Wan, Jing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Endometrial carcinoma; RNA interference; The type 1 insulin like growth factor receptor; Tumorigenicity

Indexed keywords

SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER TISSUE; CARCINOGENICITY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOMETRIUM CARCINOMA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DOWN-REGULATION; ENDOMETRIAL NEOPLASMS; FEMALE; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 79151477529     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.11.031     Document Type: Article

References (27)

1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, and T. Murray Cancer statistics, 2008 CA Cancer J Clin 58 2008 71 96
2. N. Bansal, V. Yendluri, and R.M. Wenham The molecular biology of endometrial cancers and the implications for pathogenesis, classification, and targeted therapies Cancer Control 16 2009 8 13
3. K.B. Morrison, C.E. Tognon, M.J. Garnett, C. Deal, and P.H. Sorensen ETV6-NTRK3 trans- formation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation Oncogene 21 2002 5684 5695
4. A.A. Samani, E. Chevet, L. Fallavollita, J. Galipeau, and P. Brodt Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor Cancer Res 64 2004 3380 3385
5. R. Baserga The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res 55 1995 249 252
6. A. Casamassima, and E. Rozengurt Insulin-like growth factor I stimulates tyrosine phos- phorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidy- linositol 3'-kinase and formation of a p130 (Cas). Crk complex J Biol Chem 273 1998 26149 26156
7. S. Hirano, N. Ito, S. Takahashi, and T. Tamaya Clinical implications of insulin-like growth factors through the presence of their binding proteins and receptors expressed in gynecological cancers Eur J Gynaecol Oncol 25 2004 187 191
8. Jasminka Pavelić, Branko Radaković, and Krešimir Pavelić Insulin-like growth factor -2 and its receptors (IGF-1R and IGF-2R / mannose-6-phosphate) in endometrial adenocarcinoma Gynecol Oncol 105 2007 727 735
9. C. Bahr, and B. Groner The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy Growth Horm IGF Res 14 2004 287 295
10. M. Ohtani, M. Numazaki, Y. Yajima, and Y. Fujita-Yamaguchi Mechanisms of antibody -mediated insulin-like growth factor I receptor (IGF-IR) down-regulation in MCF-7 breast cancer cells Biosci Trends 3 2009 131 138
11. S. Wolf, J. Lorenz, J. Mossner, and M. Wiedmann Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance World J Gastroenterol 16 2010 156 166
12. F. Junya, J. Christopher, M.F. Susan, P. Eigan, M.A. Lynne, and P.M. Brett Antisense oligonucleotide targeting of insulin-like growth factor-1 receptor (IGF-1R) in prostate cancer Prostate 70 2010 206 218
13. S. Pfeffer RNA silencing as a natural antiviral defense system in mammals: where are we now? Mol Ther 18 2010 871 872
14. J. Downward RNA interference BMJ 328 2004 1245 1248
15. H. Sumimoto, and Y. Kawakami The RNA silencing technology applied by lentiviral vectors in oncology Meth Mol Biol 614 2010 187 199
16. K. Lundstrom Latest development in viral vectors for gene therapy Trend Bio technol 21 2003 117 122 (Pubitemid 36293768)
17. P.L. Sinn, A.C. Arias, K.A. Brogden, and P.B. McCray Jr. Lentivirus vector can be re- administered to nasal epithelia without blocking immune responses J Virol 82 2008 10684 10692
18. H. Werner For debate: the pathophysiological significance of IGF-I receptor over expression: new insights Pediatr Endocrinol Rev 7 2009 2 5
19. A.Q. Dong, M.J. Kong, Z.Y. Ma, J.F. Qian, and X.H. Xu Down-regulation of IGF-1R using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice Cell Biol Int 31 2007 500 507
20. W.S. Liu, H.J. Yan, R.Y. Qin, R. Tian, M. Wang, and J.X. Jiang siRNA directed against survivin enhances pancreatic cancer cell gemcitabine chemosensitivity Dig Dis Sci 54 2009 89 96
21. K. Yavari, M. Taghikhani, M.G. Maragheh, S.A. Mesbah-Namin, and M.H. Babaei Knock- down of IGF-IR by RNAi inhibits SW480 colon cancer cells growth in vitro Arch Med Res 40 2009 235 240
22. T. Chen, and C. Deng Inhibitory effect of siRNA targeting survivin in gastric cancer MGC -803 cells Int Immunopharmacol 8 2008 1006 1011
23. P. Manilla, T. Rebello, C. Afable, X. Lu, V. Slepushkin, and L.M. Humeau Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector Hum Gene Ther 16 2005 17 25
24. A. Bank, R. Dorazio, and P. Leboulch A phase I/II clinical trial of beta-globin gene the- rapy for beta-thalassemia Ann NY Acad Sci 1054 2005 308 316
25. D.A. Rubinson, C.P. Dillon, A.V. Kwiatkowski, C. Sievers, L. Yang, and J. Kopinja A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference Nat Genet 33 2003 401 406
26. Y. Niwa, H. Kanda, Y. Shikauchi, A. Saiura, K. Matsubara, and T. Kitagawa Methy- lation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK /STAT and FAK signalings in human hepatocellular carcinoma Oncogene 24 2005 6406 6417
27. G. Zhang, X. Li, L. Zhang, L. Zhao, J. Jiang, and J. Wang The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells Cancer Genet Cytogenet 200 2010 140 148